Abstract: It is provided a nanogel compound comprising a) a nanogel matrix component chosen from the group consisting of poly(N-isopropylacrylamide), poly(N-isopropyl methacrylamide), poly(N,N-diethylacrylamide), poly(N-ethylmethacrylamide), polyglycerol, polyglycerol derivatives and combinations thereof and b) a first or second conjugation component which forms an interpenetrating or semi-interpenetrating network with the nanogel matrix component. Thereby, the first conjugation component is a charged component chosen from the group consisting of acids, methacrylates, methacrylamides, acrylamides and combinations thereof and the second conjugation component is a conjugated polymer chosen from the group consisting of polyaniline, polypyrrole, poly(N—(C1-C10)alkyl aniline), poly(3,4-ethylenedioxythiophene), 2-ethylhexylcyclopentadithiophene-co-2,1,3-benzothiadiazole, 2-ethylhexylcyclopentadithiophene-co-2,1,3-benzoselenadiazole, and combinations thereof.

Abstract: The invention relates to medical devices and, more in particular, to medical devices suitable for use as stents that contain an antimicrobial coating and, optionally, a drug customized to patients requirements. The invention also relates to methods for obtaining devices having the above features.

Abstract: Disclosed herein is a system and method for monitoring structures of interest in a host system that is isolated and independent of the CPU and of the operating system. The system does not modify a monitored host's software and operates properly even when the host system has been compromised. The monitor of the present disclosure monitors the integrity of the examined structure by calculating values of the structure, comparing them with expected values, and sending error reports once the discrepancy between these values is detected.

Abstract: A host system integrity monitor for monitoring memory, operating systems, applications, domain manager, and other host system's structures of interest is isolated and independent of the CPU and operating system of commodity systems. The system requires no modifications to the protected (monitored) host's software, and operates correctly even when the host system is compromised. Either arranged as a stand-alone computer on the add-in card which communicates with the monitored host system through the PCI bus, or as the co-processor based monitor located on the motherboard of the host system, or residing on one of the virtual CPU while the monitored system resides on another virtual CPU, or residing within the domain manager of the host system, the monitor monitors the integrity of the examined structure by calculating hash values of the structure, comparing them with expected hash values, and sending error reports once the discrepancy between these values is detected.

Abstract: The invention comprises compounds which are derived from a drug or a substance with therapeutic properties, and useful as reagents for the synthesis of biostable polymers including said drug in their backbone, namely polyurethanes, polyureas or polyurea urethanes that are biocompatible and biostable. The invention also comprises the processes for preparing the compounds and the polymers, and to the use of these polymers for the manufacture of medical devices.

Abstract: New triflusal-containing polymeric compounds resulting from the polymerization of 2-(methacryloyloxy)ethyl 2-acetyloxy-4-(trifluoromethyl)benzoate with butyl acrylate are described. These new polymers exhibit good adhesion and crack-bridging properties and are particularly suitable for the coating of stents.

Abstract: It comprises compounds which are derived from a drug or a substance with therapeutic properties, and useful as reagents for the synthesis of biostable polymers including said drug in their backbone, namely polyurethanes, polyureas or polyurea urethanes that are biocompatible and biostable. It also comprises the processes for preparing the compounds and the polymers, as well as to the use of these polymers for the manufacture of medical devices.

Abstract: A host system integrity monitor for monitoring memory, operating systems, applications, domain manager, and other host system's structures of interest is isolated and independent of the CPU and operating system of commodity systems. The system requires no modifications to the protected (monitored) host's software, and operates correctly even when the host system is compromised. Either arranged as a stand-alone computer on the add-in card which communicates with the monitored host system through the PCI bus, or as the co-processor based monitor located on the motherboard of the host system, or residing on one of the virtual CPU while the monitored system resides on another virtual CPU, or residing within the domain manager of the host system, the monitor of the present invention monitors the integrity of the examined structure by calculating hash values of the structure, comparing them with expected hash values, and sending error reports once the discrepancy between these values is detected.

Abstract: New triflusal-containing polymeric compounds resulting from the polymerization of 2-(methacryloyloxy)ethyl 2-acetyloxy-4-(trifluoromethyl)benzoate with butyl acrylate are described. These new polymers exhibit good adhesion and crack-bridging properties and are particularly suitable for the coating of stents.