Patents by Inventor Maria Omella Tinti

Maria Omella Tinti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Camptothecins Conjugated in Position 7 to Cyclic Peptides as Cytostatic Agents
    Publication number: 20080033003
    Abstract: Compounds of Formula (I) are described in which the R1 group is as defined in the specification and includes the condensation of the camptothecin molecule in position 7 with a cyclopeptide containing the RGD sequence. Said compounds are endowed both with high affinity for integrin receptors ?v?3 and ?v?5 and with selective cytotoxic activity on human tumour cell lines at micromolar concentrations.
    Type: Application
    Filed: May 4, 2005
    Publication date: February 7, 2008
    Inventors: Claudio Pisano, Giuseppe Giannini, Maria Omella Tinti, Loredana Vesci, Domenico Alloatti, Sergio Penco, Alma Dal Pozzo, Ni Minghong, Sabrina Dallavalle, Lucio Merlini, Franco Zunino
  • 7-Polyaminoalkyl(oxy)iminomethylcamptothecins bearing protective groups
    Publication number: 20070043067
    Abstract: Compounds are disclosed with the general formula in which the groups are as defined in the description here below and characterized by the presence of polyamine substituents on the imine/oxime residue, such amine groups being in turn protected by suitable protective groups. Said compounds are endowed with potent topoisomerase I inhibiting activity and therefore are useful as medicaments for the treatment of tumours and viral and parasite infections.
    Type: Application
    Filed: July 6, 2004
    Publication date: February 22, 2007
    Inventors: Giuseppe Giannini, Claudio Pisano, Loredana Vesci, Maria Omella Tinti, Lucio Merlini, Sergio Penco, Franco Zunino