Patents by Inventor Maria Paola De Filippis

Maria Paola De Filippis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted metal-phthalocyanines, their preparation and the use thereof
    Patent number: 7749991
    Abstract: The present invention is directed to metal-phthalocyanines of general formula (I) to the corresponding conjugates, the processes for their preparation and use in the photodynamic therapy of microbial infections (viral, bacterial and mycotic), tumor, pre-cancerous and proliferative pathologies and/or in the diagnosis, as well as for blood and blood derivatives sterilization.
    Type: Grant
    Filed: November 16, 2006
    Date of Patent: July 6, 2010
    Assignee: L. Molteni & C. Dei Fratelli Alitti-Societa di Esercizio S.p.A.
    Inventors: Gabrio Roncucci, Lia Fantetti, Maria Paola De Filippis, Donata Dei, Giulio Jori
  • Separation of regioisomers of metal phthalocyanines
    Patent number: 7265100
    Abstract: The present invention refers to a process for the separation of regioisomeric mixtures of metal phthalocyanines of formula (I), to the regioisomers obtained by this process, and their use as phototherapeutic and photodiagnostic agents
    Type: Grant
    Filed: October 28, 2002
    Date of Patent: September 4, 2007
    Assignee: L. Molteni & C. Dei Fratelli Alitti Societa' di Esercizio S.p.A.
    Inventors: Gabrio Roncucci, Francesca Giuntini, Donata Dei, Maria Paola De Filippis, Paolo Sarri, Marco Possenti, Valentina Paschetta, Giacomo Chiti
  • Metal substituted non-centrosimmetrical phthalocyanine analogues, their preparation and use in photodynamic therapy and in vivo diagnostic
    Patent number: 7153841
    Abstract: Phthalocyanine analogues having an active group able to link the phthalocyanine t carriers molecules and phthalocyanine to carriers molecules and phthalocyanine analogues as phthalocyanine-carrier conjugates showing enhanced photodynamic properties, red shifted absorption characteristic, all useful for photodynamic therapy, are described. Photosensitizers themselves or the photosensitizers-carriers conjugates are useful compounds either for treatment of various infectious diseases, the in vivo eradication of micro-organisms as well as diseases characterized by cellular hyperproliferation, in particular tumours psoriasis, actinic keratosis, atheromas, endoarterial hyperplasia and prostate hyperplasia. The above compounds can be also useful for blood and blood derivatives sterilization and in vivo/vitro diagnostics.
    Type: Grant
    Filed: March 20, 2002
    Date of Patent: December 26, 2006
    Assignee: L. Molteni & C. Dei Fratelli Alitti Societa Di Esercizio S.p.A.
    Inventors: Gabrio Roncucci, Donata Dei, Maria Paola De Filippis, Lia Fantetti, Daniele Nistri
  • Substituted metal-phthalocyanines, their preparation and the use thereof
    Patent number: 7144879
    Abstract: The present invention is directed to metal-phthalocyanines of general formula (I) to the corresponding conjugates, the processes for their preparation and use in the photodynamic therapy of microbial infections (viral, bacterial and mycotic), tumor, pre-cancerous and proliferative pathologies and/or in the diagnosis, as well as for blood and blood derivatives sterilization
    Type: Grant
    Filed: June 11, 2001
    Date of Patent: December 5, 2006
    Assignee: L. Molteni & C. Dei Fratelli
    Inventors: Gabrio Roncucci, Lia Fantetti, Maria Paola De Filippis, Donata Dei, Giulio Jori
  • Metal substituted non centrosimmetrical phthalocyanine analogues, their preparation and use in photodynamic theraphy and in vivo diagnostic
    Publication number: 20040156787
    Abstract: Phthalocyanine analogues having an active able to link the phthalocyanine t carriers molecules and phthalocyanine analogues as phthalocyanine-carrier conjugates showing enhanced photodynamic properties, red shifted absorption characteristic, all useful for photodynamic therapy, are described. Photosensitizers themselves or the photosensitizers-carriers conjugates are useful compounds either for treatment of various infectious diseases, the in vivo eradication of micro-organisms as well as diseases characterized by cellular hyperproliferation, in particular tumours psoriasis, actinic keratosis, atheromas, endoarterial hyperplasia and prostate hyperplasia. The above compounds can be also useful for blood and blood derivatives sterilization and in vivo/vitro diagnostics.
    Type: Application
    Filed: April 1, 2004
    Publication date: August 12, 2004
    Inventors: Gabrio Roncucci, Donata Dei, Maria Paola De Filippis, Lia Fantetti, Daniele Nistri
  • Substituted metal-phthalocyanines, their preparation and the use thereof
    Publication number: 20030170178
    Abstract: The present invention is directed tometal-phthalocyanines of general formula (I) to the corresponding conjugates, the processes for their preparation and use in the photodynamic therapy of microbial infections (viral, bacterial and mycotic), tumor, pre-cancerous and proliferative pathologies and/or in the diagnosis, as well as for blood and blood derivatives sterilization.
    Type: Application
    Filed: December 16, 2002
    Publication date: September 11, 2003
    Inventors: Gabrio Roncucci, Lia Fantetti, Maria Paola De Filippis, Donata Dei, Giulio Jori
  • Zinc-phthalocyanines and corresponding conjugates, their preparation and use in photodynamic therapy and as diagnostic agents
    Patent number: 5965598
    Abstract: The present invention refers to zinc-phthalocyanines of general formula (I) ##STR1## to processes for their preparation and to their use as phototherapeutic and photodiagnostic agents as free molecules and as conjugates with macromolecular carrier molecules.
    Type: Grant
    Filed: August 13, 1998
    Date of Patent: October 12, 1999
    Assignee: Molteni L. & C. dei Fratelli Alitti Societa di esercizio S.p.A.
    Inventors: Gabrio Roncucci, Donata Dei, Maria Paola De Filippis, Lia Fantetti, Ilaria Masini, Barbara Cosimelli, Giulio Jori