Patents by Inventor Maria REITMEIR

Maria REITMEIR has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing a recombinant protein of interest by using the Ntechnology
    Patent number: 9677107
    Abstract: Disclosed is a method for producing a recombinant protein of interest, the method being characterized in by the following steps: (a) providing a fusion protein comprising an Npro autoprotease moiety and a protein of interest moiety in inclusion bodies, (b) solubilizing the inclusion bodies, (c) allowing the fusion protein to be cleaved by the Npro autoprotease moiety under chaotropic conditions, wherein the recombinant protein of interest is cleaved from the fusion protein and wherein the recombinant protein of interest is not yet renatured or simultaneously renatured, and (d) recovering the protein of interest, optionally including a renaturing step for the protein of interest.
    Type: Grant
    Filed: December 19, 2013
    Date of Patent: June 13, 2017
    Assignees: SANDOZ AG, BOEHRINGER INGELHEIM RCV GMBH & CO KG
    Inventors: Maria Reitmeir, Rainer Schneider, Bernhard Auer
  • METHOD FOR PRODUCING A RECOMBINANT PROTEIN OF INTEREST
    Publication number: 20140170702
    Abstract: Disclosed is a method for producing a recombinant protein of interest, the method being characterised in by the following steps: (a) providing a fusion protein comprising an Npro autoprotease moiety and a protein of interest moiety in inclusion bodies, (b) solubilising the inclusion bodies, (c) allowing the fusion protein to be cleaved by the Npro autoprotease moiety under chaotropic conditions, wherein the recombinant protein of interest is cleaved from the fusion protein and wherein the recombinant protein of interest is not yet renatured or simultaneously renatured, and (d) recovering the protein of interest, optionally including a renaturing step for the protein of interest.
    Type: Application
    Filed: December 19, 2013
    Publication date: June 19, 2014
    Applicants: Boehringer Ingelheim RCV GmbH & Co KG, Sandoz AG
    Inventors: Maria REITMEIR, Rainer SCHNEIDER, Bernhard AUER