Patents by Inventor Maria Ribecco-Lutkiewicz

Maria Ribecco-Lutkiewicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human blood brain barrier model
    Patent number: 11820975
    Abstract: An in vitro population of human brain endothelial cells (hBECs) expressing claudin-5, occludin, ZO-1 and GLUT-1 and expressing one or more of FZD7, WNT7A, WNT7B, APCDD1, STRA6 and ZO-3 is provided. A blood brain barrier (BBB) comprising the hBECs and use of the BBB for analyzing permeability characteristics of a test agent are provided.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: November 21, 2023
    Assignee: National Research Council of Canada
    Inventors: Mahmud Bani, Danica Stanimirovic, Maria Ribecco-Lutkiewicz
  • HUMAN BLOOD BRAIN BARRIER MODEL
    Publication number: 20170362584
    Abstract: An in vitro population of human brain endothelial cells (hBECs) expressing claudin-5, occludin, ZO-1 and GLUT-1 and expressing one or more of FZD7, WNT7A, WNT7B, APCDD1, STRA6 and ZO-3 is provided. A blood brain barrier (BBB) comprising the hBECs and use of the BBB for analyzing permeability characteristics of a test agent are provided.
    Type: Application
    Filed: December 9, 2015
    Publication date: December 21, 2017
    Applicant: National Research Council of Canada
    Inventors: Mahmud Bani, Danica Stanimirovic, Maria Ribecco-Lutkiewicz