Abstract: The present invention provides IP4-4,6 substituted derivatives, their methods of synthesis and their uses. In some aspects, the IP4-4,6 derivative is a compound of formula I wherein R1, R3, R7, and R11 are OPO32?, and R5 and R9 are selected from the group consisting of —O(Alkyl)nX, —O(Alkyl)yCy(Alkyl2)y-Z, —O(Alkyl)yA(Alkyl)y-Z?, and their thiophosphate analogs. Also provided are methods, pharmaceutical compositions and formulations, methods of use, articles of manufacture, and kits for the treatment of diseases and conditions such as pathological crystallization-related diseases and conditions.

Abstract: Examples are described herein for using medical test results to trigger routine for medical supply replenishment. In various examples, based on a result of a medical test administered to a subject at a first medical facility, it may be determined that the subject has an exogenous medical condition. In response to determining that the subject has the exogenous medical condition, a message may be transmitted over a computer network from a computing device associated with the first medical facility to a remote computing device associated with a second medical facility. The message may trigger the remote computing device to initiate a routine to replenish medical supplies associated with the exogenous medical condition at the second medical facility.

Abstract: Embodiments herein relate in vitro methods of stem cell differentiation into thyroid hormone producing cells and tissues, and methods of use of these cells.

Abstract: In an example, a method includes receiving print data indicative of an image to be printed on a substrate. The print data may indicate an image portion in which an image is present and a void portion in which the image is absent. An amount of background print agent to be applied to a region of the substrate corresponding to the locations of the image portion and the void portion on the substrate when the image is printed may be determined. In examples, the amount of background print agent determined to be applied to a region of the substrate corresponding to the location of the void portion on the substrate when the image is printed is greater than the amount of a background print agent to be applied to the region of the substrate corresponding to the location of the image portion on the substrate when the image is printed.

Abstract: In an example, a method includes receiving print data indicative of an image to be printed on a substrate. The print data may indicate an image portion in which an image is present and a void portion in which the image is absent. An amount of background print agent to be applied to a region of the substrate corresponding to the locations of the image portion and the void portion on the substrate when the image is printed may be determined. In examples, the amount of background print agent determined to be applied to a region of the substrate corresponding to the location of the void portion on the substrate when the image is printed is greater than the amount of a background print agent to be applied to the region of the substrate corresponding to the location of the image portion on the substrate when the image is printed.

Abstract: In an embodiment, a first signal is generated in response to movement of a media transport assembly and a second signal is generated.

Abstract: Inkjet printing of barcodes is enhanced by several methods. In a printhead having two staggered columns of nozzles, using only the even (or odd) column enhances resolution of a vertical barcode element. Filling interior portions of the barcode element with the odd (or even) column improves barcode appearance. Barcode swelling, due to ink migration after application, is reduced by use of a depletion matrix to lessen the quantity of ink applied. Application of the depletion matrix to the edges of the barcode elements resists swelling where resolution is most required. Where a printing mask is applied to the edges of the barcode elements, the edges may be printed only by one column of printhead nozzles, or only during one direction of printhead movement, or both. Alternately, removal of one or more pixels along the edge of a barcode element allows each barcode element to swell to the desired size.

Abstract: A system includes a carrier, one or more printheads coupled with the carrier in a defined spatial relation, and alignment information associated with the carrier and identifying the defined spatial relation of one or more printheads.

Abstract: A method performed by an inkjet printing system is provided. The method comprises detecting an amount of use of a printhead and providing a request to service the printhead to a user in response to detecting the amount of use.

Abstract: In an embodiment, a first signal is generated in response to movement of a media transport assembly and a second signal is generated.

Abstract: A conveyer has a belt and an encoded surface that moves with the belt that can be re-encoded.

Abstract: A printing system includes an ink reservoir, a support, a fluid conduit and a printhead assembly. The fluid conduit is fluidly coupled to the ink reservoir and includes a first fluid coupler. The printhead assembly includes a body configured to be releasably coupled to the support, a plurality of printheads coupled to the body including a first printhead and a second printhead, and a fluid passage fluidly coupled to both the first printhead and the second printhead. The fluid passage includes a second fluid coupler releasably coupled to the first fluid coupler.

Abstract: A system includes a carrier, one or more printheads coupled with the carrier in a defined spatial relation, and alignment information associated with the carrier and identifying the defined spatial relation of one or more printheads.

Abstract: A method for evaluating an image forming device includes forming an object on a print medium. A light beam is scanned along a scan line that intersects the object. Reflectance data corresponding to the scan line is obtained. The image forming device is evaluated according to the reflectance data.

Abstract: A program creates a unitary mask for use over a whole image, with one pattern. The mask need not be full image size; it may be tiled. In the field a printer forms a mask and prints with it, best in the same session, before another image needing another mask, whether due to different image activity or type, or operating conditions. Constraints are controlled to ensure solution. Printout can start before a mask (even the part needed to finish a top swath) is done, going columnwise in each swath. In other invention facets, a program forms a mask of size significant relative to the program and prints with it. Other facets check print conditions and form adapted masks; or find nozzles that cannot back up a known-failed nozzle and to back it up form masks with all able nozzles; or assess image activity and inject mask randomness accordingly.

Abstract: Various embodiments include methods and systems for monitoring a production line for non-printing events, and responsive to detecting an event, ascertaining whether an operation can be effected with an inkjet printer stationed along the production line.

Abstract: A printing system includes an ink reservoir, a support, a fluid conduit and a printhead assembly. The fluid conduit is fluidly coupled to the ink reservoir and includes a first fluid coupler. The printhead assembly includes a body configured to be releasably coupled to the support, a plurality of printheads coupled to the body including a first printhead and a second printhead, and a fluid passage fluidly coupled to both the first printhead and the second printhead. The fluid passage includes a second fluid coupler releasably coupled to the first fluid coupler.

Abstract: In accordance with one embodiment, a system comprises a print head assembly comprising a plurality of ink-ejecting nozzles and a drying station downstream of the print head assembly and configured to produce and emit air proximate a print media. A deflector is mounted between the print head assembly and the drying station and is configured to deflect an amount of the air that is produced by the drying station.

Abstract: Systems, methods, and devices are provided for printhead adjustment. In one apparatus embodiment, the apparatus includes an image scanning mechanism and a controller. The image scanning mechanism can provide positioning data about the position of drops of ink ejected onto media from nozzles of a number of stationary printheads. The controller can determine a Y axis offset of at least two ink drops based on the positioning data.

Abstract: A program with complete conditions for a usable mask yields a unitary mask, each try. One mask pattern is used throughout an image, but may be “tiled”. Preferably the program, for given mask position, expresses favorability of several candidate pass numbers as a “neighborhood constraint” in the form of a weight; distills the weights into one weight for each pass number; based on that, chooses a number for the position; and iterates for all positions. Many preferences are very useful, e. g. automatically balancing randomness vs. determinism, and several generalized relative notations. Another invention facet uses an input text file of mask constraints; a program reads constraints from the file, applies them, forms a mask and stores/uses it. Another reprocesses a mask for best image quality, fixing its own imperfections of first-round mask forming.