Patents by Inventor Maria Sizova

Maria Sizova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • EXTRACELLULAR VESICLE PREPARATIONS
    Publication number: 20240058271
    Abstract: Provided herein are solutions and dried forms of extracellular vesicles (EVs) that are useful as therapeutic agents, and therapeutic compositions thereof.
    Type: Application
    Filed: December 14, 2021
    Publication date: February 22, 2024
    Inventors: Derek Dorman, Kevin Huynh, Laura Jackson, Collin McKenna, Maria Sizova, Bill Wang
  • COMPOSITIONS AND METHODS FOR TREATING DISEASES AND DISORDERS USING FOURNIERELLA MASSILIENSIS
    Publication number: 20230302061
    Abstract: Provided herein are methods and pharmaceutical compositions related to the bacteria and microbial extracellular vesicles (mEVs) of Fournierella massiliensis that are useful as therapeutic agents.
    Type: Application
    Filed: June 11, 2021
    Publication date: September 28, 2023
    Inventors: Alicia Ballok, Loise Francisco-Anderson, Kevin Huynh, Valeria Kravitz, Audrey McBride, Tyler Rommel, Maria Sizova
  • COMPOSITIONS AND METHODS FOR TREATING DISEASES AND DISORDERS USING OSCILLOSPIRACEAE MICROBIAL EXTRACELLULAR VESICLES
    Publication number: 20230263838
    Abstract: Provided herein are methods and pharmaceutical compositions related to microbial extracellular vesicles (mEVs) obtained from Oscillospiraceae bacteria that can be useful as therapeutic agents.
    Type: Application
    Filed: June 11, 2021
    Publication date: August 24, 2023
    Inventors: Alicia Ballok, Loise Francisco-Anderson, Maria Sizova
  • PREVOTELLA HISTICOLA STRAIN C AS AN ORAL THERAPY FOR INFLAMMATORY DISEASES
    Publication number: 20230256032
    Abstract: Provided herein are methods and pharmaceutical compositions related to the bacteria and microbial extracellular vesicles (mEVs) of Prevotella histicola Strain C that are useful as therapeutic agents, e.g., for treating inflammatory diseases (e.g., a neuroinflammatory disease).
    Type: Application
    Filed: July 20, 2021
    Publication date: August 17, 2023
    Inventors: Mark Bodner, William Caffry, Taylor A. Cormack, Valeria Kravitz, Alline Pacheco, Holly Ponichtera, Kritika Ramani, Maria Sizova, Leslie Wardwell-Scott
  • COMPOSITIONS AND METHODS FOR TREATING DISEASES AND DISORDERS USING HARRYFLINTIA ACETISPORA
    Publication number: 20230218683
    Abstract: Provided herein are methods and pharmaceutical compositions related to the bacteria and microbial extracellular vesicles (mEVs) of Harryflintia acetispora that are useful as therapeutic agents.
    Type: Application
    Filed: June 11, 2021
    Publication date: July 13, 2023
    Inventors: Alicia Ballok, Loise Francisco-Anderson, Kevin Huynh, Valeria Kravitz, Audrey McBride, Tyler Rommel, Maria Sizova
  • METHODS AND COMPOSITIONS FOR CULTURING HEMOGLOBIN-DEPENDENT BACTERIA
    Publication number: 20230220328
    Abstract: Provided herein are compositions and methods related to culturing bacteria (such as hemoglobin-dependent bacteria) with a heme-containing polypeptide (such as a heme-containing polypeptide that is not sourced from an animal and/or can be recombinantly produced).
    Type: Application
    Filed: November 25, 2020
    Publication date: July 13, 2023
    Inventors: Valeria Kravitz, Manas Ray, Maria Sizova
  • PROCESSED MICROBIAL EXTRACELLULAR VESICLES
    Publication number: 20220296654
    Abstract: Provided herein are methods and pharmaceutical compositions related to processed microbial extracellular vesicles (pmEVs) that can be useful as therapeutic agents.
    Type: Application
    Filed: June 11, 2020
    Publication date: September 22, 2022
    Inventors: Alicia Ballok, Mark Bodmer, Baundauna Bose, Sofia M. Carlton, Taylor A. Cormack, Christopher J.H. Davitt, Loise Francisco-Anderson, Brian Goodman, Andrea ltano, Nihal Okan, Holly Ponichtera, Erin B. Troy, Fabian B. Romano-Chernac, Maria Sizova
  • METHODS AND COMPOSITIONS FOR CULTURING HEMOGLOBIN-DEPENDENT BACTERIA
    Publication number: 20220267716
    Abstract: Provided herein are methods and compositions related to culturing hemoglobin-dependent bacteria.
    Type: Application
    Filed: July 31, 2020
    Publication date: August 25, 2022
    Inventors: Valeria Kravitz, Maria Sizova
  • SECRETED MICROBIAL EXTRACELLULAR VESICLES
    Publication number: 20220249579
    Abstract: Provided herein are methods and pharmaceutical compositions related to secreted microbial extracellular vesicles (smEVs) that can be useful as therapeutic agents.
    Type: Application
    Filed: June 11, 2020
    Publication date: August 11, 2022
    Inventors: Alicia Ballok, Mark Bodmer, Baundauna Bosse, Sofia M. Carlton, Taylor A. Cormack, Christopher J. Davitt, Loise Francisco-Anderson, Brian Goodman, Andrea Itano, Nihal Okan, Holly Ponichtera, Erin B. Troy, Fabian B. Romano-Chernac, Maria Sizova
  • COMPOSITIONS AND METHODS FOR TREATING IMMUNE DISORDERS USING IMMUNE MODULATING LACTOCOCCUS BACTERIA STRAINS
    Publication number: 20220211773
    Abstract: Provided herein are methods and compositions related to immune modulating Lactococcus strains useful as therapeutic agents. In certain embodiments, provided herein are methods of treating an immune disorder in a subject comprising administering to the subject a bacterial composition comprising Lactococcus lactis cremoris Strain A (ATCC Deposit Number PTA-125368).
    Type: Application
    Filed: January 25, 2022
    Publication date: July 7, 2022
    Inventors: Brian Goodman, Holly Ponichtera, Andrea Itano, Mark Bodmer, Taylor A. Cormack, Maria Sizova, Carolina Baez-Giangreco, Duncan McHale, Kritika Ramani
  • Compositions and methods for treating immune disorders using immune modulating bacteria strains
    Patent number: 11266700
    Abstract: Provided herein are methods and compositions related to immune modulating Lactococcus strains useful as therapeutic agents. In certain embodiments, provided herein are methods of treating an immune disorder in a subject comprising administering to the subject a bacterial composition comprising Lactococcus lactis cremoris Strain A (ATCC Deposit Number PTA-125368).
    Type: Grant
    Filed: November 15, 2018
    Date of Patent: March 8, 2022
    Assignee: Evelo Biosciences, Inc.
    Inventors: Brian Goodman, Holly Ponichtera, Andrea Itano, Mark Bodmer, Taylor A. Cormack, Maria Sizova, Carolina Baez-Giangreco, Duncan McHale, Kritika Ramani
  • Compositions and methods for treating cancer and immune disorders using bacteria
    Patent number: 11090341
    Abstract: Provided herein are methods and compositions related to Veillonella bacteria useful as therapeutic agents.
    Type: Grant
    Filed: February 6, 2019
    Date of Patent: August 17, 2021
    Assignee: Evelo Biosciences, Inc.
    Inventors: Brian Goodman, Baundauna Bose, Christopher J. H. Davitt, Maria Sizova, Sofia M. R. Carlton, Andrea Itano, Holly Ponichtera, Taylor A. Cormack, Kritika Ramani
  • COMPOSITIONS AND METHODS OF TREATING CANCER USING BIFIDOBACTERIUM ANIMALIS SSP. LACTIS
    Publication number: 20210093680
    Abstract: Provided herein are methods and compositions related to Bifidobacterium animalis ssp. lactis useful as therapeutic agents.
    Type: Application
    Filed: August 26, 2020
    Publication date: April 1, 2021
    Inventors: Peter Sandy, Jacqueline Papkoff, Maria Sizova, Brian Goodman, Humphrey Gardner, Holly Ponichtera, William Caffry, Anupriya Dutta, Hank Wu
  • COMPOSITIONS AND METHODS FOR TREATING IMMUNE DISORDERS USING LACHNOSPIRACEAE BACTERIA
    Publication number: 20210052669
    Abstract: Provided herein are methods and compositions related to Lachnospiraceae bacteria useful as therapeutic agents.
    Type: Application
    Filed: January 31, 2019
    Publication date: February 25, 2021
    Inventors: Maria Sizova, Carolina Baez-Giangreco, Brian Goodman, Holly Ponichtera, Peter Sandy
  • Compositions and methods of treating cancer using ssp.
    Patent number: 10792314
    Abstract: Provided herein are methods and compositions related to Bifidobacterium animalis ssp. lactis useful as therapeutic agents.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: October 6, 2020
    Assignee: Evelo Biosciences, Inc.
    Inventors: Peter Sandy, Jacqueline Papkoff, Maria Sizova, Brian Goodman, Humphrey Gardner, Holly Ponichtera, Hank Wu, William Caffry, Anupriya Dutta
  • Pharmaceutical compositions comprising a strain
    Patent number: 10702561
    Abstract: Provided herein are pharmaceutical compositions related to a Blautia strain useful as a therapeutic agent.
    Type: Grant
    Filed: October 7, 2019
    Date of Patent: July 7, 2020
    Assignee: Evelo Biosciences, Inc.
    Inventors: Brian Goodman, Holly Ponichtera, Andrea Itano, Taylor A. Cormack, Maria Sizova, Valeria Kravitz, Ekaterina Gavrish, Carolina Baez-giangreco
  • Method of treating cancer using ssp. strain PTA-125097
    Patent number: 10576111
    Abstract: Provided herein are methods and compositions related to Bifidobacterium animalis ssp. lactis useful as therapeutic agents.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: March 3, 2020
    Assignee: Evelo Biosciences, Inc.
    Inventors: Peter Sandy, Jacqueline Papkoff, Maria Sizova, Brian Goodman, Humphrey Gardner, Holly Ponichtera
  • Pharmaceutical Compositions Comprising a Blautia Strain
    Publication number: 20200030389
    Abstract: Provided herein are pharmaceutical compositions related to a Blautia strain useful as a therapeutic agent.
    Type: Application
    Filed: October 7, 2019
    Publication date: January 30, 2020
    Inventors: Brian Goodman, Holly Ponichtera, Andrea Itano, Taylor A. Cormack, Maria Sizova, Valeria Kravitz, Ekaterina Gavrish, Carolina Baez-giangreco
  • Compositions and methods for treating disease using a strain
    Patent number: 10493113
    Abstract: Provided herein are methods and compositions related to Blautia Strain A useful as therapeutic agents.
    Type: Grant
    Filed: November 14, 2018
    Date of Patent: December 3, 2019
    Assignee: Evelo Biosciences, Inc.
    Inventors: Brian Goodman, Holly Ponichtera, Andrea Itano, Taylor A. Cormack, Maria Sizova, Valeria Kravitz, Ekaterina Gavrish, Carolina Baez-Giangreco
  • COMPOSITIONS AND METHODS FOR TREATING CANCER AND IMMUNE DISORDERS USING VEILLONELLA BACTERIA
    Publication number: 20190350987
    Abstract: Provided herein are methods and compositions related to Veillonella bacteria useful as therapeutic agents.
    Type: Application
    Filed: February 6, 2019
    Publication date: November 21, 2019
    Inventors: Brian Goodman, Baundauna Bose, Christopher J.H. Davitt, Maria Sizova, Sofia M.R. Carlton, Andrea Itano, Holly Ponichtera, Taylor A. Cormack