Patents by Inventor Maria T. Abreu

Maria T. Abreu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutations in NOD2 are associated with fibrostenosing disease in patients with Crohn's disease
    Patent number: 7790370
    Abstract: The present invention provides a method of diagnosing or predicting susceptibility to a clinical subtype of Crohn's disease characterized by fibrostenosing disease by determining the presence or absence in an individual of a fibrostenosis-predisposing allele linked to a NOD2/CARD15 locus, where the presence of the fibrostenosis-predisposing allele is diagnostic of or predictive of susceptibility to the clinical subtype of Crohn's disease characterized by fibrostenosing disease. In a method of the invention, the clinical subtype of Crohn's disease can be, for example, characterized by fibrostenosing disease independent of small bowel involvement.
    Type: Grant
    Filed: July 30, 2003
    Date of Patent: September 7, 2010
    Assignee: Cedars-Sinai Medical Center
    Inventors: Maria T. Abreu, Kent D. Taylor, Jerome I. Rotter, Huiying Yang, Stephan R. Targan
  • Mutations in NOD2 are associated with fibrostenosing disease in patients with Crohn's disease
    Publication number: 20040053263
    Abstract: The present invention provides a method of diagnosing or predicting susceptibility to a clinical subtype of Crohn's disease characterized by fibrostenosing disease by determining the presence or absence in an individual of a fibrostenosis-predisposing allele linked to a NOD2/CARD15 locus, where the presence of the fibrostenosis-predisposing allele is diagnostic of or predictive of susceptibility to the clinical subtype of Crohn's disease characterized by fibrostenosing disease. In a method of the invention, the clinical subtype of Crohn's disease can be, for example, characterized by fibrostenosing disease independent of small bowel involvement.
    Type: Application
    Filed: January 30, 2003
    Publication date: March 18, 2004
    Inventors: Maria T. Abreu, Kent D. Taylor, Jerome I. Rotter, Huiying Yang, Kazuhito Sugimura, Stephan R. Targan