Patents by Inventor Maria Teresa Lamy-Freund

Maria Teresa Lamy-Freund has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthesis of a potent parmagnetic agonist (epm-3) of the melanocyte stimulating hormone containing amino acid-type stable free radical
    Publication number: 20030212251
    Abstract: The present invention refers to the chemical synthesis and potentiality for application in several biochemical assays, of a potent agonist of the &agr;-melanocyte stimulating hormone (&agr;-MSH), labeled with an amino acid-type paramagnetic spin probe (Toac, or 2,2,6,6-tetramethylpiperidine-1-oxyl-amino-4-carboxylic acid), valuable for use in electron spin resonance and fluorescence allowing biochemical-clinical investigation of relevant physiological roles of &agr;-MSH in animal organism. The referred analogue of the present invention, acetil-Toac0-(Nle4, DPhe7)-&agr;-MSH, where (Nle4, DPhe7)-&agr;-(MSH is nominated commercially as Melanotan™ and although containing a non-natural compound in its structure such as Toac, maintained entirely its potent agonist potency.
    Type: Application
    Filed: October 28, 2002
    Publication date: November 13, 2003
    Inventors: Clovis Ryuichi Nakaie, Simone Dos Reis Barbosa, Eduardo Maffud Cilli, Maria Teresa Lamy-Freund, Armando Siuiti Ito, Maria Aparecida Visconti, Ana Maria De Lauro Castrucci