Patents by Inventor Maria Theodora Van Den Barselaar

Maria Theodora Van Den Barselaar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antimicrobial peptides derived from ubiquicidine
    Patent number: 6884776
    Abstract: The invention relates to the use of ubiquicidine or optionally modified peptide fragments derived therefrom for the preparation of a drug for the treatment, diagnostics or prophylaxis of infections in humans and animals. A peptide fragment derived from ubiquicidine comprises for instance a preferably continuous series of at least 3, preferably at least 7-13 amino acids from the amino acid sequence of ubiquicidine; KVHGSLARAGKVRGQTPKVAKQEKKKKKTGRAKRRMQYNRRFVNVVPTFGKKKGPN ANS (SEQ ID NO: 1). Hybrid molecules comprise for instance a cationic peptide with an antimicrobial action and/or a peptide fragment of ubiquicidine and/or a derivative thereof and one or more effector molecules.
    Type: Grant
    Filed: May 18, 1998
    Date of Patent: April 26, 2005
    Assignee: RijksUniversiteit Leiden
    Inventors: Petrus Hendricus Nibbering, Pieter Sicco Hiemstra, Maria Theodora Van Den Barselaar, Ernest Karel Jacob Pauwels, Rolf Ide Johannes Feitsma