Patents by Inventor Maria-Therese Melki

Maria-Therese Melki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Monitoring and inhibiting human immunodeficiency virus infection by modulating HMGB1 dependent triggering of HIV-1 replication and persistence
    Patent number: 8603766
    Abstract: Compositions and methods for modulating human immunodeficiency virus (HIV) infection involving substances that inhibit the ability of high mobility box 1 (HMGB1) protein to interact with natural killer (NK) cells. Therapeutic compositions comprising antibodies and drugs, such as glycyrrhizin, which bind to HMGB1. Methods of detecting or monitoring HIV infection involving detection or quantitation of HMGB1 or antibodies specific for HMGB1 in a biological sample.
    Type: Grant
    Filed: September 11, 2009
    Date of Patent: December 10, 2013
    Assignee: Institut Pasteur
    Inventors: Marie-Lise Gougeon, Hela Saidi, Maria-Therese Melki, Beatrice Poirier-Beaudoin, Valerie Seffer
  • Monitoring and inhibiting human immunodeficiency virus infection by modulating HMGB1 dependent triggering of HIV-1 replication and persistence
    Patent number: 8450076
    Abstract: Compositions and methods for modulating human immunodeficiency virus (HIV) infection involving substances that inhibit the ability of high mobility box 1 (HMGB1) protein to interact with natural killer (NK) cells. Therapeutic compositions comprising antibodies and drugs, such as glycyrrhizin, which bind to HMGB1. Methods of detecting or monitoring HIV infection involving detection or quantitation of HMGB1 or antibodies specific for HMGB1 in a biological sample.
    Type: Grant
    Filed: September 11, 2009
    Date of Patent: May 28, 2013
    Assignee: Institut Pasteur
    Inventors: Marie-Lise Gougeon, Héla Saidi, Maria-Thérèse Melki, Béatrice Poirier-Beaudoin, Valérie Seffer
  • MONITORING AND INHIBITING HUMAN IMMUNODEFICIENCY VIRUS INFECTION BY MODULATING HMGB1 DEPENDENT TRIGGERING OF HIV-1 REPLICATION AND PERSISTENCE
    Publication number: 20110229474
    Abstract: Compositions and methods for modulating human immunodeficiency virus (HIV) infection involving substances that inhibit the ability of high mobility box 1 (HMGB1) protein to interact with natural killer (NK) cells. Therapeutic compositions comprising antibodies and drugs, such as glycyrrhizin, which bind to HMGB1. Methods of detecting or monitoring HIV infection involving detection or quantitation of HMGB1 or antibodies specific for HMGB1 in a biological sample.
    Type: Application
    Filed: September 11, 2009
    Publication date: September 22, 2011
    Applicant: INSTITUT PASTEUR
    Inventors: Marie-Lise Gougeon, Hela Saidi, Maria-Therese Melki, Beatrice Poirier-Beaudoin, Valerie Seffer