Patents by Inventor Maria Victoria Gonzalez Fajardo

Maria Victoria Gonzalez Fajardo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Loading of hydrophobic drugs into hydrophilic polymer delivery systems
    Patent number: 8586098
    Abstract: A process is described for loading hydrophilic polymer particles with a water-insoluble solvent-soluble drug. The particles are preferably embolic agents. The method provides particles having little or no drug at the surface and in a surface layer, whereby the burst effect is minimised. The drug is precipitated in the core of the particle, leading to extended release. The drug is, for instance, paclitaxel, rapamycin, dexamethasone or ibuprofen.
    Type: Grant
    Filed: June 15, 2011
    Date of Patent: November 19, 2013
    Assignee: Biocompatibles UK Limited
    Inventors: Andrew Lennard Lewis, Yiqing Tang, Maria Victoria Gonzalez Fajardo
  • DRUG DELIVERY FROM EMBOLIC AGENTS
    Publication number: 20120276151
    Abstract: An embolic composition comprises microspheres formed of water-insoluble water-swellable anionic polymer having swollen diameter more than 100 ?m and a cationic camptothecin compound, preferably irinotecan. The microspheres are preferably formed of crosslinked polyvinylalcohol, preferably of ethylenically unsaturated polyvinylalcohol macromer, crosslinked with anionic ethylenically unsaturated anionic comonomer. The compositions are used to treat hypervascular tumours for instance colorectal metastases of the liver.
    Type: Application
    Filed: October 27, 2011
    Publication date: November 1, 2012
    Applicant: BIOCOMPATIBLES UK LIMITED
    Inventors: Andrew Lennard Lewis, Peter William Stratford, Maria Victoria Gonzalez. Fajardo, Yiqing Tang
  • DRUG DELIVERY FROM EMBOLIC AGENTS
    Publication number: 20120201867
    Abstract: An embolic composition comprises microspheres formed of water-insoluble water-swellable anionic polymer having swollen diameter more than 100 ?m, and a cationic camptothecin compound, preferably irinotecan. The microspheres are preferably formed of crosslinked polyvinylalcohol, preferably of ethylenically unsaturated polyvinylalcohol macromer, crosslinked with anionic ethylenically unsaturated anionic comonomer. The compositions are used to treat hypervascular tumours for instance colorectal metastases of the liver.
    Type: Application
    Filed: April 20, 2012
    Publication date: August 9, 2012
    Applicant: BIOCOMPATIBLES UK LIMITED
    Inventors: Andrew Lennard LEWIS, Peter William STRATFORD, Maria Victoria GONZALEZ.FAJARDO, Yiqing TANG
  • LOADING OF HYDROPHOBIC DRUGS INTO HYDROPHILIC POLYMER DELIVERY SYSTEMS
    Publication number: 20110293731
    Abstract: A process is described for loading hydrophilic polymer particles with a water-insoluble solvent-soluble drug. The particles are preferably embolic agents. The method provides particles having little or no drug at the surface and in a surface layer, whereby the burst effect is minimised. The drug is precipitated in the core of the particle, leading to extended release. The drug is, for instance, paclitaxel, rapamycin, dexamethasone or ibuprofen.
    Type: Application
    Filed: June 15, 2011
    Publication date: December 1, 2011
    Applicant: BIOCOMPATIBLES UK LIMITED
    Inventors: Andrew Lennard LEWIS, Yiqing TANG, Maria Victoria GONZALEZ FAJARDO
  • Loading of hydrophobic drugs into hydrophilic polymer delivery systems
    Patent number: 8007831
    Abstract: A process is described for loading hydrophilic polymer particles with a water-insoluble solvent-soluble drug. The particles are preferably embolic agents. The method provides particles having little or no drug at the surface and in a surface layer, whereby the burst effect is minimised. The drug is precipitated in the core of the particle, leading to extended release. The drug is, for instance, paclitaxel, rapamycin, dexamethasone or ibuprofen.
    Type: Grant
    Filed: February 9, 2007
    Date of Patent: August 30, 2011
    Assignee: Biocompatibles UK Limited
    Inventors: Andrew Lennard Lewis, Yiqing Tang, Maria Victoria Gonzalez Fajardo
  • LOADING OF HYDROPHOBIC DRUGS INTO HYDROPHILIC POLYMER DELIVERY SYSTEMS
    Publication number: 20100166876
    Abstract: A process is described for loading hydrophilic polymer particles with a water-insoluble solvent-soluble drug. The particles are preferably embolic agents. The method provides particles having little or no drug at the surface and in a surface layer, whereby the burst effect is minimised. The drug is precipitated in the core of the particle, leading to extended release. The drug is, for instance, paclitaxel, rapamycin, dexamethasone or ibuprofen.
    Type: Application
    Filed: February 9, 2007
    Publication date: July 1, 2010
    Applicant: BIOCOMPATIBLES UK LIMITED
    Inventors: Andrew Lennard Lewis, Yiqing Tang, Maria Victoria Gonzalez Fajardo