Patents by Inventor Maria Victoria Montenegro-Chamarro

Maria Victoria Montenegro-Chamarro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for the identification of inhibitors of 5-aminolevulinate synthase as antibiotics
    Patent number: 6689578
    Abstract: The present inventors have discovered that 5-Aminolevulinate synthase is essential for fungal pathogenicity. Specifically, the inhibition of 5-Aminolevulinate synthase gene expression in fungi results in no signs of successful infection or lesions. Thus, 5-Aminolevulinate synthase can be used as a target for the identification of antibiotics, preferably antifungals. Accordingly, the present invention provides methods for the identification of compounds that inhibit 5-Aminolevulinate synthase expression or activity. The methods of the invention are useful for the identification of antibiotics, preferably antifungals.
    Type: Grant
    Filed: December 6, 2001
    Date of Patent: February 10, 2004
    Assignee: Paradigm Genetics, Inc.
    Inventors: Todd DeZwaan, Sze-Chung Lo, Maria Victoria Montenegro-Chamarro, Sheryl Frank, Blaise Darveaux, Sanjoy K. Mahanty, Ryan Heiniger, Amy Skalchunes, Huaqin Pan, Rex Tarpey, Jeffrey Shuster, Matthew M. Tanzer, Lisbeth Hamer, Kiichi Adachi
  • METHODS FOR THE IDENTIFICATION OF INHIBITORS OF 5-AMINOLEVULINATE SYNTHASE AS ANTIBIOTICS
    Publication number: 20030124642
    Abstract: The present inventors have discovered that 5-Aminolevulinate synthase is essential for fungal pathogenicity. Specifically, the inhibition of 5-Aminolevulinate synthase gene expression in fungi results in no signs of successful infection or lesions. Thus, 5-Aminolevulinate synthase can be used as a target for the identification of antibiotics, preferably antifungals. Accordingly, the present invention provides methods for the identification of compounds that inhibit 5-Aminolevulinate synthase expression or activity. The methods of the invention are useful for the identification of antibiotics, preferably antifungals.
    Type: Application
    Filed: December 6, 2001
    Publication date: July 3, 2003
    Inventors: Todd DeZwaan, Sze-Chung Lo, Maria Victoria Montenegro-Chamarro, Sheryl Frank, Blaise Darveaux, Sanjoy K. Mahanty, Ryan Heiniger, Amy Skalchunes, Huaqin Pan, Rex Tarpey, Jeffrey Shuster, Matthew M. Tanzer, Lisbeth Hamer, Kiichi Adachi