Abstract: A method, involving determining a first distribution of a first parameter associated with an error or residual in performing a device manufacturing process; determining a second distribution of a second parameter associated with an error or residual in performing the device manufacturing process; and determining a distribution of a parameter of interest associated with the device manufacturing process using a function operating on the first and second distributions. The function may include a correlation.

Abstract: There is provided a method for handling an updated profile of a first network function (NF) node of a service producer in a network. The method is performed by a network repository function (NRF) node. Priority information for the first NF node is removed (602) from the updated profile received from the first NF node if the NRF node previously changed the priority information. The priority information is for use by the network node in selecting an NF node of a service producer to provide a service requested by a second NF node of a service consumer. The priority information is indicative of a priority with which the first NF node is to be selected relative to at least one other NF node of the service producer. Transmission (604) of the updated profile, with the priority information removed, is initiated towards the network node.

Abstract: Provided herein are compositions and methods for the treatment of cancers using modified TILs, wherein the modified TILs include one or more immunomodulatory agents (e.g., cytokines) associated with their cell surface. The immunomodulatory agents associated with the TILs provide a localized immunostimulatory effect that can advantageously enhance TIL survival, proliferation and/or anti-tumor activity in a patient recipient. As such, the compositions and methods disclosed herein provide effective cancer therapies.

Abstract: The present disclosure relates to IL2 agonists with improved therapeutic profiles.

Abstract: Provided herein are compositions and methods for the treatment of cancers using modified TILs, wherein the modified TILs include one or more immunomodulatory agents (e.g., cytokines) associated with their cell surface. The immunomodulatory agents associated with the TILs provide a localized immunostimulatory effect that can advantageously enhance TIL survival, proliferation and/or anti-tumor activity in a patient recipient. As such, the compositions and methods disclosed herein provide effective cancer therapies.

Abstract: The present invention provides a heterocyclic compound having an orexin type 2 receptor agonist activity. A compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof has an orexin type 2 receptor agonist activity, and is useful as an agent for the prophylaxis or treatment of narcolepsy.

Abstract: Provided herein are compositions and methods for the treatment of cancers using modified TILs, wherein the modified TILs include one or more immunomodulatory agents (e.g. cytokines) associated with their cell surface. The immunomodulatory agents associated with the TILs provide a localized immunostimulatory effect that can advantageously enhance TIL survival, proliferation and/or anti-tumor activity in a patient recipient. As such, the compositions and methods disclosed herein provide effective cancer therapies.

Abstract: The present disclosure relates to IL2 agonists with improved therapeutic profiles.

Abstract: Disclosed herein are compounds of the formula: A-L-R1(I), wherein the these variables are defined herein, as well as medical devices comprising said compounds. The present disclosure also provides pharmaceutical compositions comprising the compounds or medical devices disclosed herein. Further, the present disclosure provides methods of treatment using the compounds, medical devices, or pharmaceutical compositions disclosed herein.

Abstract: A method and a device for non-contact determination of temporal color and/or intensity variations in objects in a scene. Monoscopic overview images of the scene are detected with first and second overview cameras from two different viewing directions, and calculated to form a stereoscopic overview map. A two-dimensional detail image is detected by a detail camera from a third viewing direction and is projected on the overview map. Measurement surfaces in the scene are selected based on criteria which are predetermined depending on parameters on which conclusions are to be drawn from the color variations and/or intensity variations. Light emitted by the measurement surfaces is detected in a spatially-resolved and wavelength-resolved manner in a continuously-captured series of measurement images in a predetermined spectral range. The measurement surfaces are analyzed in the measurement images with respect to temporal variation of the intensity and/or color of the light, and the results displayed.

Abstract: Disclosed are systems and methods for improving interactions with and between computers in a content system supported by or configured with personal computing devices, servers and/or platforms. The systems interact to identify and retrieve data across platforms, which data can be used to improve the quality of data used in processing interactions between or among processors in such systems. The disclosed systems and methods determine breaking or trending news stories from social media activity, which are then communicated to users via personalized delivery. Thus, the disclosed systems and methods leverage social data, expert knowledge and/or user feedback, which are all available on-line, to determine breaking news stories, which are then delivered to users in a personalized manner specific to each user.

Abstract: Disclosed are systems and methods for improving interactions with and between computers in a content system supported by or configured with personal computing devices, servers and/or platforms. The systems interact to identify and retrieve data across platforms, which data can be used to improve the quality of data used in processing interactions between or among processors in such systems. The disclosed systems and methods determine breaking or trending news stories from social media activity, which are then communicated to users via personalized delivery. Thus, the disclosed systems and methods leverage social data, expert knowledge and/or user feedback, which are all available on-line, to determine breaking news stories, which are then delivered to users in a personalized manner specific to each user.