Patents by Inventor Marian Seto

Marian Seto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DIMERIC MOLECULAR COMPLEXES WITH FREE CYSTEINE RESIDUES AND CONJUGATES THEREOF
    Publication number: 20130259806
    Abstract: The invention relates generally to dimeric molecular complexes comprising two fusion proteins. Each fusion protein comprises a biological effector moiety, a polypeptide spacer sequence, and an IgE CH4 dimerization domain. The dimeric molecular complexes may be conjugated, at a defined site, to other molecules including drug moieties, cytotoxic agents, labels (such as detectable labels), or biocompatible polymers.
    Type: Application
    Filed: December 7, 2011
    Publication date: October 3, 2013
    Inventors: David Light, Paul Szymanski, Marian Seto, Aline Cornelius
  • Dimeric molecular complexes
    Patent number: 8501185
    Abstract: Dimeric molecular complexes useful for diagnostics and therapeutics.
    Type: Grant
    Filed: May 24, 2007
    Date of Patent: August 6, 2013
    Assignee: Bayer Healthcare LLC
    Inventors: Tara Renee Heitner Hansen, David Light, Kirk McLean, Renate Parry, Noboru Satozawa, Douglas Schneider, Marian Seto
  • Antibody Mimetic Scaffolds
    Publication number: 20120302492
    Abstract: Provided herein are protein scaffolds, e.g. antibody mimetic scaffolds, comprising a three finger protein domain that specifically bind to target molecules, polynucleotides encoding such proteins, methods of using such proteins, and libraries of such scaffolds.
    Type: Application
    Filed: November 1, 2010
    Publication date: November 29, 2012
    Applicant: BAYER HEALTHCARE LLC
    Inventors: Richard Harkins, Fang Jin, Ye Jin, Marian Seto
  • DIMERIC MOLECULAR COMPLEXES
    Publication number: 20110104058
    Abstract: Dimeric molecular complexes comprising an IgE CH4 dimerization domain useful for diagnostics and therapeutics.
    Type: Application
    Filed: May 24, 2007
    Publication date: May 5, 2011
    Applicant: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Tara Heitner, David Light, Kirk McLean, Renate Parry, Noboru Satozawa, Douglas Schneider, Marian Seto
  • Modified ligands for receptor tyrosine kinases
    Patent number: 5840687
    Abstract: The invention provides for synthetic ligands that bind to class I receptor tyrosine kinases. The ligands are analogous in structure to naturally occurring ligands. The modified ligands however, have eliminated the mid-sequence (B) domain present in the native ligands and replaced it with a peptide bridge which links the amino (A) and carboxy (C) domains.
    Type: Grant
    Filed: February 2, 1995
    Date of Patent: November 24, 1998
    Assignee: Schering Aktiengesellschaft
    Inventors: Richard N. Harkins, Marian Seto, Bradley A. Katz