Patents by Inventor Mariana Valencia CASTANHEIRA FERREIRA LEAO

Mariana Valencia CASTANHEIRA FERREIRA LEAO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tryptophanol-derived oxazoloisoindolinones: small-molecule P53 activators
    Patent number: 9732091
    Abstract: The present application discloses novel family of Tryptophanol-Derived Oxazoloisoindolinones for use in the treatment of p53 associated conditions, such as cancer. These compounds are p53 activators and may be used in pharmaceutical compositions, alone or in combination with other chemotherapeutic agents.
    Type: Grant
    Filed: June 26, 2014
    Date of Patent: August 15, 2017
    Assignees: UNIVERSIDADE DO PORTO, FACULDADE DE FARMACIA DA UNIVERSIDADE DE LISBOA
    Inventors: Lucilia Helena Ataide Saraiva, Maria Manuel Duque Vieira Marques Dos Santos, Nuno Alexandre Lousa Pereira, Clara Isabel Ferreira Pereira, Sara Gomes Moreira, Mariana Valencia Castanheira Ferreira Leao, Angelo Filipe Almeida Monteiro, Joana Oliveira Gama Soares
  • TRYPTOPHANOL-DERIVED OXAZOLOISOINDOLINONES: SMALL-MOLECULE P53 ACTIVATORS
    Publication number: 20160347765
    Abstract: The present application discloses novel family of Tryptophanol-Derived Oxazoloisoindolinones for use in the treatment of p53 associated conditions, such as cancer. These compounds are p53 activators and may be used in pharmaceutical compositions, alone or in combination with other chemoterapeutic agents.
    Type: Application
    Filed: June 26, 2014
    Publication date: December 1, 2016
    Inventors: Lucilia Helena ATAIDE SARAIVA, Maria Manuel DUQUE VIEIRA MARQUES DOS SANTOS, Nuno Alexandre LOUSA PEREIRA, Clara Isabel FERREIRA PEREIRA, Sara GOMES MOREIRA, Mariana Valencia CASTANHEIRA FERREIRA LEAO, Angelo Filipe ALMEIDA MONTEIRO, Joana OLIVEIRA GAMA SOARES