Patents by Inventor Mariane Bandeira Melo

Mariane Bandeira Melo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for heterologous repRNA immunizations
    Patent number: 11964007
    Abstract: Compositions and methods are described for inducing an immune response against an immunogen in humans. The induced immune response is obtained by administering a heterologous prime-boost combination of an in vitro transcribed (IVT) self-replicating RNA (repRNA) and an adenovirus vector. The compositions and methods can be used to provide a protective immunity against a disease, such as a viral infection or a cancer, in humans.
    Type: Grant
    Filed: December 22, 2021
    Date of Patent: April 23, 2024
    Assignees: Janssen Vaccines & Prevention B.V., Massachusetts Institute of Technology
    Inventors: Ronald Vogels, Marijn Van Der Neut Kolfschoten, Darrell J. Irvine, Ron Weiss, Ely Blanton Porter, Mariane Bandeira Melo, Tasuku Kitada
  • Layer-by-layer nanoparticles for cytokine therapy in cancer treatment
    Patent number: 11964026
    Abstract: Disclosed are particles for delivering cytokinese, such as IL-12, for the treatment of cancer. The particles comprise cytokines non-covalently bound to liposomes, where the liposomes are coated with polyelectrolytes.
    Type: Grant
    Filed: August 22, 2022
    Date of Patent: April 23, 2024
    Assignee: Massachusetts Institute of Technology
    Inventors: Antonio Eric Barberio, Santiago Correa Echavarria, Mariane Bandeira Melo, Talar Tokatlian, Erik Christopher Dreaden, Paula T. Hammond, Darrell J. Irvine
  • LAYER-BY-LAYER NANOPARTICLES FOR CYTOKINE THERAPY IN CANCER TREATMENT
    Publication number: 20230201367
    Abstract: Disclosed are particles for delivering cytokinese, such as IL-12, for the treatment of cancer. The particles comprise cytokines non-covalently bound to liposomes, where the liposomes are coated with polyelectrolytes.
    Type: Application
    Filed: August 22, 2022
    Publication date: June 29, 2023
    Inventors: Antonio E. Barberio, Santiago Correa Echavarria, Mariane Bandeira Melo, Talar Tokatlian, Erik Christopher Dreaden, Paula T. Hammond, Darrell J. Irvine
  • Layer-by-layer nanoparticles for cytokine therapy in cancer treatment
    Patent number: 11419947
    Abstract: Disclosed are particles for delivering cytokinese, such as IL-12, for the treatment of cancer. The particles comprise cytokines non-covalently bound to liposomes, where the liposomes are coated with polyelectrolytes.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: August 23, 2022
    Assignee: Massachusetts Institute of Technology
    Inventors: Antonio Eric Barberio, Santiago Correa Echavarria, Mariane Bandeira Melo, Talar Tokatlian, Erik Christopher Dreaden, Paula T. Hammond, Darrell J. Irvine
  • Methods and Compositions for Heterologous repRNA Immunizations
    Publication number: 20220111033
    Abstract: Compositions and methods are described for inducing an immune response against an immunogen in humans. The induced immune response is obtained by administering a heterologous prime-boost combination of an in vitro transcribed (IVT) self-replicating RNA (repRNA) and an adenovirus vector. The compositions and methods can be used to provide a protective immunity against a disease, such as a viral infection or a cancer, in humans.
    Type: Application
    Filed: December 22, 2021
    Publication date: April 14, 2022
    Inventors: Ronald Vogels, Marijn Van Der Neut Kolfschoten, Darrell Irvine, Ron Weiss, Ely Porter, Mariane Bandeira Melo, Tasuku Kitada
  • Methods and compositions for heterologous repRNA immunizations
    Patent number: 11235051
    Abstract: Compositions and methods are described for inducing an immune response against an immunogen in humans. The induced immune response is obtained by administering a heterologous prime-boost combination of an in vitro transcribed (IVT) self-replicating RNA (repRNA) and an adenovirus vector. The compositions and methods can be used to provide a protective immunity against a disease, such as a viral infection or a cancer, in humans.
    Type: Grant
    Filed: July 27, 2018
    Date of Patent: February 1, 2022
    Assignees: Janssen Vaccines & Prevention B.V., Massachusetts Institute of Technology
    Inventors: Ronald Vogels, Marijn Van Der Neut Kolfschoten, Darrell J. Irvine, Ron Weiss, Ely Blanton Porter, Mariane Bandeira Melo, Tasuku Kitada
  • METHODS AND COMPOSITIONS FOR HETEROLOGOUS REPRNA IMMUNIZATIONS
    Publication number: 20200230225
    Abstract: Compositions and methods are described for inducing an immune response against an immunogen in humans. The induced immune response is obtained by administering a heterologous prime-boost combination of an in vitro transcribed (IVT) self-replicating RNA (repRNA) and an adenovirus vector. The compositions and methods can be used to provide a protective immunity against a disease, such as a viral infection or a cancer, in humans.
    Type: Application
    Filed: July 27, 2018
    Publication date: July 23, 2020
    Inventors: Ronald VOGELS, Marijn VAN DER NEUT KOLFSCHOTEN, Darrell J. IRVINE, Ron WEISS, Ely Blanton PORTER, Mariane Bandeira MELO, Tasuku KITADA
  • LAYER-BY-LAYER NANOPARTICLES FOR CYTOKINE THERAPY IN CANCER TREATMENT
    Publication number: 20190125895
    Abstract: Disclosed are particles for delivering cytokinese, such as IL-12, for the treatment of cancer. The particles comprise cytokines non-covalently bound to liposomes, where the liposomes are coated with polyelectrolytes.
    Type: Application
    Filed: October 30, 2018
    Publication date: May 2, 2019
    Inventors: Antonio Eric Barberio, Santiago Correa Echavarria, Mariane Bandeira Melo, Talar Tokatlian, Erik Christopher Dreaden, Paula T. Hammond, Darrell J. Irvine