Patents by Inventor Marianna Jackson
Marianna Jackson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 5863773Abstract: Disclosed are novel antifungal agents having the formula: ##STR1## as well as a pharmaceutically acceptable salt, ester of prodrug thereof, whereinR is: ##STR2## --C(O)--R.sub.1 wherein R.sub.1 is alkyl, alkenyl, aryl, arylalkenyl, aryl-aryl-, arylalkoxy-aryl-, aryl-aryl-aryl-, arylkoxy-aryl-aryl-, or ##STR3## wherein R.sub.2 is alkylamino, dialkylamino, (heterocyclic)alkyl, aryl, or arylalkyl; andX is O, NH, or NR.sub.3 wherein R.sub.3 is alkyl or aryl. Also disclosed are pharmaceutical compositions comprising a compound of the invention in combination with a pharmaceutically acceptable carrier; and a process for preparing the compounds of the invention.Type: GrantFiled: September 30, 1997Date of Patent: January 26, 1999Assignee: Abbott LaboratoriesInventors: Geewananda P. Gunawardana, David Frost, Marianna Jackson, James P. Karwowski, Ronald R. Rasmussen
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Patent number: 5773421Abstract: Novel antifungal agents having the formula: ##STR1## wherein R is hydrogen or --C(O)--R.sub.1 wherein R.sub.1 is alkenyl, C.sub.2 -C.sub.12 -alkyl, aryl, arylalkenyl, arylalkyl, aryl-aryl-, arylalkoxy-aryl-, aryloxyl-aryl-, aryl-aryl-aryl- or arylalkoxy-aryl-aryl-, or pharmaceutically acceptable salts, esters or prodrugs thereof, as well as (i) pharmaceutical compositions comprising such compounds, (ii) methods of treatment using such compounds, and (iv) methods and fungal cultures useful in making the same.Type: GrantFiled: December 21, 1995Date of Patent: June 30, 1998Assignee: Abbott LaboratoriesInventors: Lisa A. Alder, Marianna Jackson, Neal S. Burres, James B. McAlpine, Jill E. Hochlowski, Larry L. Klein, Paul A. Lartey, Clinton Yeung
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Patent number: 5767096Abstract: Antimicrobial compounds having the formula ##STR1## wherein R.sup.1 and R.sup.2 are independently selected from the group consisting of hydrogen and C.sub.1 -to-C.sub.4 alkanoyl;R.sup.3 and R.sup.4 are selected from the group consisting of(a) R.sup.3 is hydrogen and R.sup.4 is hydroxy,(b) R.sup.3 is hydroxy and R.sup.4 is hydrogen,(c) R.sup.3 and R.sup.4 taken together are .dbd.O; or selected from the group consisting of hydrogen and hydroxy; andR.sup.5 and R.sup.6 are independently selected from the group consisting of hydrogen, bromine and chlorine, with the proviso that at least one of R.sup.5 and R.sup.6 must be bromine. Also disclosed are pharmaceutical compositions comprising such compounds, methods of treating bacterial infection by the administration thereof and a process for preparing said compounds.Type: GrantFiled: July 12, 1996Date of Patent: June 16, 1998Assignee: Abbott LaboratoriesInventors: Jill E. Hochlowski, Marianna Jackson, James B. McAlpine, Ronald R. Rasmussen
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Patent number: 5589485Abstract: Novel antifungal and antitumor agents having the formula ##STR1## as well as pharmaceutically acceptable salts, esters, amides and pro-drugs thereof, wherein R is selected from the group consisting of ##STR2## Also disclosed are pharmaceutical compositions comprising such compounds, and methods of treatment and processes of manufacture relating thereto.Type: GrantFiled: April 26, 1995Date of Patent: December 31, 1996Assignee: Abbott LaboratoriesInventors: Jill E. Hochlowski, Marianna Jackson, Sunil K. Kadam, James P. Karwowski, James B. McAlpine
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Patent number: 5585251Abstract: Novel antifungal agents having the formula: ##STR1## wherein R is hydrogen or a radical of the formula ##STR2## and pharmaceutically acceptable prodrugs thereof, as well as (i) pharmaceutical compositions comprising such compounds, (ii) methods of treatment using such compounds, and (iv) methods and fungal cultures useful in making the same.Type: GrantFiled: January 10, 1995Date of Patent: December 17, 1996Assignee: Abbott LaboratoriesInventors: Lisa A. Alder, Neal S. Burres, Jill E. Hochlowski, Marianna Jackson, James B. McAlpine
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Patent number: 5484799Abstract: Novel antifungal and antitumor agents having the formula ##STR1## as well as pharmaceutically acceptable salts, esters, amides and pro-drugs thereof, wherein R is selected from the group consisting of ##STR2## Also disclosed are pharmaceutical compositions comprising such compounds, and methods of treatment and processes of manufacture relating thereto.Type: GrantFiled: December 9, 1993Date of Patent: January 16, 1996Assignee: Abbott LaboratoriesInventors: Jill E. Hochlowski, Marianna Jackson, Sunil K. Kadam, James P. Karwowski, James B. McAlpine
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Patent number: 5284947Abstract: A compound having the structural formula ##STR1## or a pharmaceutically acceptable salts and prodrugs thereof, wherein R.sup.1 is selected from the group consisting of hydrogen and loweracyl, and R.sup.2 is selected from the group consisting of hydrogen, hydroxyl and methoxyl, as well as methods for the preparation and use thereof.Type: GrantFiled: September 15, 1992Date of Patent: February 8, 1994Assignee: Abbott LaboratoriesInventors: Sunil K. Kadam, Patrick E. Humphrey, Jill Hochlowski, James B. McAlpine, Marianna Jackson
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Patent number: 5192748Abstract: New antibiotics, unphenelfamycin and phenelfamycins A-D, are produced by microorganisms belonging to the genus Streptomyces. The antibiotics have antibacterial activity against gram-positive and gram-negative anaerobic organisms and are effective in improving the feed efficiency and growth rate of livestock, including poultry.Type: GrantFiled: August 5, 1991Date of Patent: March 9, 1993Assignee: Abbott LaboratoriesInventors: Jill E. Hochlowski, Mark H. Buytendorp, Randal H. Chen, James B. McAlpine, Robert J. Theriault, Marianna Jackson, James P. Karwowski
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Patent number: 5171740Abstract: A mixture of new coumamidine compounds are produced by a microorganism, belonging to the genus Saccharopolyspora. The compounds have antibiotic activity against a broad spectrum of bacteria.Type: GrantFiled: May 28, 1991Date of Patent: December 15, 1992Assignee: Abbott LaboratoriesInventors: James B. McAlpine, Robert J. Theriault, James P. Karwowski, Marianna Jackson, Randal H. Chen
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Patent number: 4918174Abstract: New compounds, tiacumicins, are produced by a microorganism belonging to the genus Dactylosporangium. The compounds are effective Gram-positive antibiotics.Type: GrantFiled: September 26, 1986Date of Patent: April 17, 1990Assignee: Abbott LaboratoriesInventors: James B. McAlpine, Marianna Jackson, James Karwowski