Patents by Inventor Marianna Lovasz nee Gaspar

Marianna Lovasz nee Gaspar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 2,3,4-trinor-1,5-inter-meta-phenylene-prostacyclin compounds useful in inhibiting thrombocyte aggregation
    Patent number: 4638002
    Abstract: The invention relates to new 2,3,4-trinor-1,5-inter-m-phenylene-PGI.sub.2 derivatives of the formula (I) ##STR1## wherein A stands for carboxy, cyano, tetrazolyl or --COOR.sup.3 or --CONR.sup.1 R.sup.2 ;R.sup.3 is C.sub.1-4 alkyl or an equivalent of a pharmacologically acceptable cation:R.sup.1 and R.sup.2 each stands for hydrogen, phenyl; C.sub.1-5 alkyl, optionally substituted by carboxy, hydroxy, phenyl or C.sub.2-5 alkoxycarbonyl; or C.sub.1-4 alkylsulfonyl; orR.sup.1 and R.sup.2 together form an .alpha.,.omega.-alkylene chain containing 3-6 carbon atoms;B stands for oxygen or methylene;Y is optionally bromo-substituted vinylene or a --C.tbd.C-- group:R.sup.4 stands for hydrogen or tetrahydro-pyran-2-yl;R.sup.5 represents an alkyl group containing 5-9 carbon atoms, which can be optionally interrupted by one or more oxygen atom(s) or --CH.dbd.CH-- or --C.tbd.
    Type: Grant
    Filed: December 30, 1983
    Date of Patent: January 20, 1987
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.
    Inventors: Istvan Szekely, Sandor Botar, Krisztina Dolgos nee Kekesi, Bela Bertok, Antal Gajary, Tamas Szabolcsi, Gabor Kovacs, Marianna Lovasz nee Gaspar
  • 7-Substituted PGI.sub.2 -derivatives and pharmaceutical compositions containing them
    Patent number: 4565827
    Abstract: The invention relates to new, 7-substituted PGI.sub.2 -derivatives of formula (I) ##STR1## The new compounds have valuable therapeutical properties, and in particular show prostacyclin-like effects.
    Type: Grant
    Filed: October 27, 1981
    Date of Patent: January 21, 1986
    Assignee: CHINOIN Gyogyszer es Vegyeszeti Termekek Gyara R.T.
    Inventors: Istvan Szekely, Marianna Lovasz nee Gaspar, Gabor Kovacs, Krisztina Kekesi, Sandor Botar, Karoly Horvath, Peter Kormoczy, Pal Hadhazy, Istvan Rakoczy, Laszlo Fesus
  • Process for the preparation of pyrethrins and analogues thereof and insecticidal compositions containing the same
    Patent number: 4281170
    Abstract: A method of making an insecticidal pyrethrin by oxidation in aprotic organic solvent. The compounds are of the formula: ##STR1## wherein R.sup.11 is straight or branched chain lower alkyl or 1-alkenyl or hydrogen;R and R.sup.12 are the same or different and are hydrogen, halogen or lower alkyl or one of the moieties R and R.sup.12 is lower alkoxycarbonyl.
    Type: Grant
    Filed: February 21, 1979
    Date of Patent: July 28, 1981
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt
    Inventors: Istvan Szekely, Marianna Lovasz nee Gaspar, Gabor Kovacs, Rudolf Soos, Lajos Nagy, Bela Koszegi
  • Chemical compounds
    Patent number: 4248888
    Abstract: Insecticidal compounds of the formula: ##STR1## wherein R.sup.11 is a straight or branched chain lower alkyl or 1-alkenyl or hydrogen;R and R.sup.12 are the same or different and are hydrogen, halogen, or straight or branched chained lower alkyl, or one of the moieties R and R.sup.12 is lower alkoxycarbonyl; the bonds represent .alpha.- and/or .beta.-configuration and the -- bonds represent .beta.-configuration.
    Type: Grant
    Filed: February 21, 1979
    Date of Patent: February 3, 1981
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara R.T.
    Inventors: Istvan Szekely, Marianna Lovasz, nee Gaspar, Gabor Kovacs, Rudolf Soos, Lajos Nagy, Bela Koszegi
  • Process for making bicyclic lactone derivatives for use as intermediates in the synthesis of prostaglandins
    Patent number: 4204999
    Abstract: A process for the preparation of optically active or racemic lactone diol derivatives of the formula ##STR1## (for use as intermediates in the Corey prostaglandin synthesis). Optically active or racemic lactone diol derivatives are inclosed, in whichR.sup.3 and R.sup.4 are the same or different and stand for a hydrogen, or a lower alkanoyl optionally substituted with one, two or three halogen atoms, or form together a ##STR2## group, in which R.sup.5 and R.sup.6 are the same or different and stand for a hydrogen, alkyl or aryl, with a process for preparing them.According to the invention the above compound are prepared by reacting optically active or racemic lactone of the formula II with formaldehyde or with a formaldehyde polymerisate, in the presence of the mixture of a strong acid and water or of a lower alkane carboxylic acid optionally substituted with one, two or three halogen atoms, and then optionally subjecting the obtained compound of the general formula I, in which R.sup.3 and/or R.sup.
    Type: Grant
    Filed: October 20, 1978
    Date of Patent: May 27, 1980
    Assignee: Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.
    Inventors: Istvan Tomoskozi, Gabor Kovacs, Istvan Szekely, Vilmos Simonidesz, Marianna Lovasz nee Gaspar, Borbala Keresztesnee Ordog, Julia Remport nee Radoczi, Istvan Stadler, Zsuzsa Visky nee Gombos, Csaba Szantay
  • Process for the preparation of bicyclic enone compounds
    Patent number: 4176122
    Abstract: A process for the preparation of bicyclic enon compounds in which a lactone diol is selectively oxidized to obtain a hydroxy-aldehyde with one hydroxyl group and, without isolation, the hydroxy-aldehyde is reacted with a phosphorus compound. The reaction product can be acylated or silylated.
    Type: Grant
    Filed: February 22, 1977
    Date of Patent: November 27, 1979
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek
    Inventors: Istvan Szekely, Istvan Tomoskozi, Gabor Kovacs, Vilmos Simonidesz, Marianna Lovasz nee Gaspar, Borbala nee Ordog Keresztes, Julia nee Radoczi Remport, Istvan Stadler, Zsuzsa nee Gombos Visky, Csaba Szantay
  • Bicyclic lactone derivatives employed as intermediates in the synthesis of prostaglandines
    Patent number: 4126622
    Abstract: A compound of the formula is disclosed. ##STR1## wherein R.sup.3 and R.sup.4 are the same or different and are each hydrogen, lower alkanoyl, lower alkanoyl substituted by 1, 2, or 3 halogen atoms, or R.sup.3 and R.sup.4 together form an ##STR2## group in which R.sup.5 and R.sup.6 are the same or different and are each hydrogen, alkyl or aryl as well as a process for the preparation thereof.
    Type: Grant
    Filed: February 22, 1977
    Date of Patent: November 21, 1978
    Assignee: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara RT
    Inventors: Istvan Tomoskozi, Gabor Kovacs, Istvan Szekely, Vilmos Simonidesz, Marianna Lovasz nee Gaspar, Borbala Keresztes nee Ordog, Julia Remport nee Radoczi, Istvan Stadler, Zsuzsa Visky nee Gombos, Csaba Szantay