Patents by Inventor Marianne B. Mogensen

Marianne B. Mogensen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rapid unylinker cleavage
    Patent number: 11542294
    Abstract: Methods for cleaving oligonucleotides from a solid support are described as are methods for synthesizing an oligonucleotide on a solid support and subsequently cleaving the oligonucleotide from the solid support. In the methods, the 3? nucleoside of the oligonucleotide attached to the solid support is a LNA nucleoside. The method entail treating the bound oligonucleotide with a concentrated ammonium hydroxide solution for about 30 minutes to about 6 hours.
    Type: Grant
    Filed: March 22, 2018
    Date of Patent: January 3, 2023
    Assignee: Roche Innovation Center Copenhagen A/S
    Inventors: Michael Meldgaard, Marianne B. Mogensen, Dennis Jul Hansen
  • Rapid Unylinker Cleavage
    Publication number: 20210292357
    Abstract: The present invention relates to the field of oligonucleotide synthesis using a solid support and in particular to the finding the when using a 3? oxy-LNA nucleoside attached to the solid support of the UnyLinker types, cleavage and deprotection occurs very rapidly.
    Type: Application
    Filed: March 22, 2018
    Publication date: September 23, 2021
    Inventors: Michael Meldgaard, Marianne B. Mogensen, Dennis Jul Hansen