Patents by Inventor Marianne Lee

Marianne Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11807670
    Abstract: It provides novel fusion proteins that are capable of self-crystallization and exhibit improved physical properties such as enhanced tolerance to organic solvents and increased thermostability. Polynucleotides encoding the fusion proteins as well as methods of making and using such fusion proteins are also described.
    Type: Grant
    Filed: July 10, 2017
    Date of Patent: November 7, 2023
    Assignee: The Chinese University of Hong Kong
    Inventors: Michael Chan, Marianne Lee, Bradley Heater
  • Publication number: 20230203105
    Abstract: Provide is a novel system for immobilizing re-combinantly produced proteins by entrapping them in crystals of co-expressed proteins that are capable of self-crystallization . Related compositions and as well as methods of making and using the immobilized proteins are also described.
    Type: Application
    Filed: April 24, 2020
    Publication date: June 29, 2023
    Inventors: Michael Chan, Bradley Heater, Marianne Lee
  • Publication number: 20230113102
    Abstract: Provided are novel recombinant proteins that are capable of self-crystallization and exhibit desirable physical properties such as enhanced cellular uptake or and endoso-mal escape. Polynucleotides encoding the recombinant proteins as well as methods of making and using such proteins are also described.
    Type: Application
    Filed: April 15, 2020
    Publication date: April 13, 2023
    Inventors: Michael Chan, Marianne Lee, Zaofeng Yang
  • Patent number: 11416360
    Abstract: A system, method, and apparatus for detecting errors in an artificial intelligence engine. The method includes processing a medical image of a patient at an artificial intelligence engine, and producing a first test result at the artificial intelligence engine based on the medical image. The method also includes detecting an error in the first test result using a server emulator, and producing a second test result that corrects the error in the first test result. In addition, the method includes transmitting the second test result from the artificial intelligence engine to a picture archiving and communication systems server.
    Type: Grant
    Filed: October 9, 2019
    Date of Patent: August 16, 2022
    Assignee: FUJIFILM MEDICAL SYSTEMS U.S.A., INC.
    Inventor: Marianne Lee
  • Publication number: 20220168739
    Abstract: A module of microfluidic device used for applying shear stress to cells (501) in order to deliver payloads (502) to the cells (501). The module includes cross junction modules (105), serpentine modules and squeezing-relaxing modules (1101). The devices and related methods result in increased payload (502) delivery and reduced loss in cell (501) viability.
    Type: Application
    Filed: April 10, 2020
    Publication date: June 2, 2022
    Inventors: Yi-Ping HO, Michael Kenneth CHAN, Ming Ming Marianne LEE, Chung Hong Nathaniel WONG, MD Habibur RAHMAN
  • Publication number: 20210109829
    Abstract: A system, method, and apparatus for detecting errors in an artificial intelligence engine. The method includes processing a medical image of a patient at an artificial intelligence engine, and producing a first test result at the artificial intelligence engine based on the medical image. The method also includes detecting an error in the first test result using a server emulator, and producing a second test result that corrects the error in the first test result. In addition, the method includes transmitting the second test result from the artificial intelligence engine to a picture archiving and communication systems server.
    Type: Application
    Filed: October 9, 2019
    Publication date: April 15, 2021
    Inventor: Marianne Lee
  • Publication number: 20190185522
    Abstract: It provides novel fusion proteins that are capable of self-crystallization and exhibit improved physical properties such as enhanced tolerance to organic solvents and increased thermostability. Polynucleotides encoding the fusion proteins as well as methods of making and using such fusion proteins are also described.
    Type: Application
    Filed: July 10, 2017
    Publication date: June 20, 2019
    Inventors: Michael CHAN, Marianne LEE, Bradley HEATER
  • Publication number: 20160291847
    Abstract: A method, apparatus and computer program product are provided in order to provide an application tagging framework. An example of the method includes receiving, via a tag selection interface, an indication of selection of at least one tag corresponding to a set of tag information stored in a tag information datastore, accessing, using a tag loader element executing via a processor, the tag information datastore to obtain the set of tag information, determining, by the tag loader element, one or more applications associated with the set of tag information, generating, by the tag loader element, an instruction to each of the one or more applications based on the set of tag information, the instruction comprising data to cause a tagging component of each of the one or more applications to applying formatting to at least one component of a user interface to indicate content of the user interface associated with the set of tag information, and transmitting the instruction to teach of the one or more applications.
    Type: Application
    Filed: March 31, 2015
    Publication date: October 6, 2016
    Inventors: Marianne Lee, Eldon Allan Wong, Itai Galili
  • Publication number: 20150278369
    Abstract: A method, apparatus and computer program product are provided in order to provide a context-aware clinical portal. An example method may include receiving an environment context. The environment context may include information relating to at least one of a user task, a user action, or an open application. The method may also include determining, based on the environment context, at least one portlet for providing clinical information related to the environment context. The at least one portlet may provide an interface control for at least one of viewing or accessing the clinical information. The method may also include generating a context-aware clinical portal comprising the at least one portlet, and providing the context-aware clinical portal.
    Type: Application
    Filed: March 28, 2014
    Publication date: October 1, 2015
    Applicant: MCKESSON FINANCIAL HOLDINGS
    Inventors: Eldon Allan Wong, Marianne Lee
  • Patent number: 8921571
    Abstract: Several different pyrrolysine analogs are disclosed in this application. Those analogs have distinct chemical and biophysical properties. Some analogs are useful in chemical ligation applications. Methods of making and using are also disclosed.
    Type: Grant
    Filed: October 6, 2010
    Date of Patent: December 30, 2014
    Assignee: The Ohio State University
    Inventors: Michael K. Chan, Tomasz Fekner, Xin Li, Marianne Lee, Manoj Nair, Jennifer Jo Ottensen
  • Publication number: 20130035478
    Abstract: Several different pyrrolysine analogs are disclosed in this application. Those analogs have distinct chemical and biophysical properties. Some analogs are useful in chemical ligation applications. Methods of making and using are also disclosed.
    Type: Application
    Filed: October 6, 2010
    Publication date: February 7, 2013
    Applicant: The Ohio State University
    Inventors: Michael K. Chan, Tomasz Fekner, Xin Li, Marianne Lee, Manoj Nair, Jennifer Jo Ottensen