Abstract: The present invention provides Annexin A5 for use in a prophylactic or therapeutic method of preventing, reducing, delaying the onset of, or delaying the progression of, direct viral damage to the vascular system and/or immune system, in a subject, wherein the viral infection is caused by a virus selected from the group consisting of (a) a virus capable of causing hemorrhagic fever (VHF), and (b) a virus that presents phosphatidylserine (PS) and mediates cell infection and/or internalisation through PS binding.

Abstract: The invention refers to a process for the preparation of a self-dispersing or self-emulsifying tablet, wherein a heated granulation mixture containing an active lipophilic substance and a surfactant is granulated into granules, said granules are cooled to a semi-solid state, said semi-solid granules are mixed with one or more fillers to cover the surface of the granules, distribution, the sieved granules are mixed with tabletting aids, and said mixture is compressed into tablets. The granulation mixture can also contain a lipid and/or filler. The invention also refers to tablets prepared by said processes.

Abstract: The invention refers to a process for the preparation of a self-dispersing or self-emulsifying tablet, wherein a heated granulation mixture containing an active lipophilic substance and a surfactant is granulated into granules, said granules are cooled to a semi-solid state, said semi-solid granules are mixed with one or more fillers to cover the surface of the granules, distribution, the sieved granules are mixed with tabletting aids, and said mixture is compressed into tablets. The granulation mixture can also contain a lipid and/or filler. The invention also refers to tablets prepared by said processes.

Abstract: The invention refers to a process for the preparation of a self-dispersing or self-emulsifying tablet comprising the steps mixing a granulation medium containing an active lipophilic substance with one or more fillers and auxiliary components, granulation of said mixture into granules, drying of said granules, sieving of the granules into a homogeneous size, mixing of the granules with tabletting aids, and compressing said mixture into tablets, which is characterised in that the granulation medium comprises an oil, a surfactant and a polar liquid. The invention also refers to a process for the preparation of tablets from a granulation medium comprising oil and surfactant, as well as to tablets prepared by said processes.