Patents by Inventor Mariano J. Scian

Mariano J. Scian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENE BIOMARKERS OF LUNG FUNCTION
    Publication number: 20130143752
    Abstract: Described herein are a group of 1,013 genes and 1 phenotypic variable are identified as candidate predictors that differentiated smokers (current or former) with or without COPD. The full predictor set can be reduced to a nine-gene classifier (IL6R, CCR2, PPP2CB, RASSF2, WTAP, DNTTIP2, GDAP1, LIPE, and RPL14) with similar performance. Also described herein is the use of the full predictor set and the reduced nine gene set in methods of diagnosing lung disease or an increased risk of developing lung disease, such as COPD, in a subject. Also described herein is the use of the full predictor set and the reduced nine gene set in methods of providing a prognosis for a subject with lung disease, such as COPD.
    Type: Application
    Filed: July 3, 2012
    Publication date: June 6, 2013
    Inventors: Jeffery S. Edmiston, Barbara K. Zedler, Edward Lenn Murrelle, Mark Leppert, Kellie J. Archer, Mariano J. Scian