Patents by Inventor Mariano Licciardi

Mariano Licciardi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nanostructured formulations for the delivery of silibinin and other active ingredients for treating ocular diseases
    Patent number: 11633356
    Abstract: Formulations are described, containing silibinin or other active ingredients incorporated in lipid nanoparticle systems of the SLN and NLC type, and based on calixarenes, possibly mucoadhesive, or in micellar and nanoparticle systems based on amphiphilic inulin copolymers for use in the treatment of neurodegenerative ocular diseases. The versatility of the calixarene compound is also described, capable of charging and releasing active ingredients characterized by low water solubility, easy chemical and enzymatic degradation, low bioavailability, either of natural origin or not, to be used in the treatment of ocular diseases.
    Type: Grant
    Filed: August 3, 2020
    Date of Patent: April 25, 2023
    Assignee: DISTRETTO TECNOLOGICO SICILIA MICRO E NANO SISTEMI S.C.A.R.L.
    Inventors: Anna Rita Blanco, Maria Luisa Bondi', Gennara Cavallaro, Grazia Maria Letizia Consoli, Emanuela Fabiola Craparo, Gaetano Giammona, Mariano Licciardi, Giovanna Pitarresi, Guiseppe Granata, Patrizia Saladino, Clara La Marca, Irene Ceidda, Salvatore Papasergi, Patrizia Guarneri, Salvatore Cuzzocrea, Emanuela Esposito, Santa Viola
  • Nanostructured formulations for the delivery of silibinin and other active ingredients for treating ocular diseases
    Patent number: 11266659
    Abstract: Formulations are described, containing silibinin or other active ingredients incorporated in lipid nanoparticle systems of the SLN and NLC type, and based on calixarenes, possibly mucoadhesive, or in micellar and nanoparticle systems based on amphiphilic inulin copolymers for use in the treatment of neurodegenerative ocular diseases. The versatility of the calixarene compound is also described, capable of charging and releasing active ingredients characterized by low water solubility, easy chemical and enzymatic degradation, low bioavailability, either of natural origin or not, to be used in the treatment of ocular diseases.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: March 8, 2022
    Assignee: DISTRETTO TECNOLOGICO SICILIA MICRO E NANO SISTEMI S.C.A.R.L.
    Inventors: Anna Rita Blanco, Maria Luisa Bondi', Gennara Cavallaro, Grazia Maria Letizia Consoli, Emanuela Fabiola Craparo, Gaetano Giammona, Mariano Licciardi, Giovanna Pitarresi, Giuseppe Granata, Patrizia Saladino, Clara La Marco, Irene Ceidda, Salvatore Papasergi, Patrizia Guarneri, Salvatore Cuzzocrea, Emanuela Esposito, Santa Viola
  • Nanostructured formulations for the delivery of silibinin and other active ingredients for treating ocular diseases
    Patent number: 11253526
    Abstract: Formulations are described, containing silibinin or other active ingredients incorporated in lipid nanoparticle systems of the SLN and NLC type, and based on calixarenes, possibly mucoadhesive, or in micellar and nanoparticle systems based on amphiphilic inulin copolymers for use in the treatment of neurodegenerative ocular diseases. The versatility of the calixarene compound is also described, capable of charging and releasing active ingredients characterized by low water solubility, easy chemical and enzymatic degradation, low bioavailability, either of natural origin or not, to be used in the treatment of ocular diseases.
    Type: Grant
    Filed: August 3, 2020
    Date of Patent: February 22, 2022
    Assignee: DISTRETTO TECNOLOGICO SICILIA MICRO E NANO SISTEMI S.C.A.R.L.
    Inventors: Anna Rita Blanco, Maria Luisa Bondi′, Gennara Cavallaro, Grazia Maria Letizia Consoli, Emanuela Fabiola Craparo, Gaetano Giammona, Mariano Licciardi, Giovanna Pitarresi, Guiseppe Granata, Patrizia Saladino, Clara La Marca, Irene Deidda, Salvatore Papasergi, Patrizia Guarneri, Salvatore Cuzzocrea, Emanuela Esposito, Santa Viola
  • NANOSTRUCTURED FORMULATIONS FOR THE DELIVERY OF SILIBININ AND OTHER ACTIVE INGREDIENTS FOR TREATING OCULAR DISEASES
    Publication number: 20220031614
    Abstract: Formulations are described, containing silibinin or other active ingredients incorporated in lipid nanoparticle systems of the SLN and NLC type, and based on calixarenes, possibly mucoadhesive, or in micellar and nanoparticle systems based on amphiphilic inulin copolymers for use in the treatment of neurodegenerative ocular diseases. The versatility of the calixarene compound is also described, capable of charging and releasing active ingredients characterized by low water solubility, easy chemical and enzymatic degradation, low bioavailability, either of natural origin or not, to be used in the treatment of ocular diseases.
    Type: Application
    Filed: August 3, 2020
    Publication date: February 3, 2022
    Inventors: Anna Rita BLANCO, Maria Luisa BONDI', Gennara CAVALLARO, Grazia Maria Letizia CONSOLI, Emanuela Fabiola CRAPARO, Gaetano GIAMMONA, Mariano LICCIARDI, Giovanna PITARRESI, Guiseppe GRANATA, Patrizia SALADINO, Clara LA MARCA, Irene CEIDDA, Salvatore PAPASERGI, Patrizia GUARNERI, Salvatore CUZZOCREA, Emanuela ESPOSITO, Santa VIOLA
  • NANOSTRUCTURED FORMULATIONS FOR THE DELIVERY OF SILIBININ AND OTHER ACTIVE INGREDIENTS FOR TREATING OCULAR DISEASES
    Publication number: 20210046083
    Abstract: Formulations are described, containing silibinin or other active ingredients incorporated in lipid nanoparticle systems of the SLN and NLC type, and based on calixarenes, possibly mucoadhesive, or in micellar and nanoparticle systems based on amphiphilic inulin copolymers for use in the treatment of neurodegenerative ocular diseases. The versatility of the calixarene compound is also described, capable of charging and releasing active ingredients characterized by low water solubility, easy chemical and enzymatic degradation, low bioavailability, either of natural origin or not, to be used in the treatment of ocular diseases.
    Type: Application
    Filed: August 3, 2020
    Publication date: February 18, 2021
    Inventors: Anna Rita BLANCO, Maria Luisa BONDI', Gennara CAVALLARO, Grazia Maria Letizia CONSOLI, Emanuela Fabiola CRAPARO, Gaetano GIAMMONA, Mariano LICCIARDI, Giovanna PITARRESI, Guiseppe GRANATA, Patrizia SALADINO, Clara LA MARCA, Irene CEIDDA, Salvatore PAPASERGI, Patrizia GUARNERI, Salvatore CUZZOCREA, Emanuela ESPOSITO, Santa VIOLA
  • AMPHIPHILIC COPOLYMERS THEIR PREPARATION AND USE FOR THE DELIVERY OF DRUGS
    Publication number: 20190031834
    Abstract: New amphiphilic polymers of formula (I) are described; the process for their preparation and their use as carriers for pharmaceutical drugs is also described.
    Type: Application
    Filed: October 9, 2014
    Publication date: January 31, 2019
    Inventors: Anna Rita BLANCO, Gennara CAVALLARO, Gaetano GIAMMONA, Mariano LICCIARDI, Glovanna PITARRESI, Domenico TROMBETTA
  • Ophthalmic Pharmaceutical Composition Containing Amphiphilic Polyaspartamide Copolymers
    Publication number: 20090221545
    Abstract: The present invention relates in general to the use of amphiphilic graft-type copolymers of polyaspartamide for the ophthalmic administration of drugs, such as for example steroidal and non-steroidal anti-inflammatory agents, antimicrobial agents such as aminoglycosides, macrolides, cephalosporin, tetracycline, quinolones, penicillin, beta-lactams, anti-glaucoma agents such as prostaglandins, alpha- and beta-blockers, inhibitors of carbonic anhydrase, cannabinoids, antiviral agents, diagnostic agents, anti-angiogenic agents, antioxidants.
    Type: Application
    Filed: March 15, 2007
    Publication date: September 3, 2009
    Applicant: SIFI S.P.A.
    Inventors: Gaetano Giammona, Gennara Cavallaro, Mariano Licciardi, Claudine Civiale, Grazia Maria Paladino, Maria Grazia Mazzone