Patents by Inventor Maria Pia Abbracchio

Maria Pia Abbracchio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS FOR USE IN PROGRESSIVE MULTIPLE SCLEROSIS
    Publication number: 20240148745
    Abstract: The present invention provides compounds able to induce neuroprotection of damaged neurons and boost the remyelination potential of oligodendrocytes. The compounds have been identified through methods of pharmacological screening of a small molecule library consisting of known pharmacologically active compounds and approved drugs. The screening method is also included in the invention.
    Type: Application
    Filed: March 9, 2022
    Publication date: May 9, 2024
    Applicants: FONDAZIONE CENTRO SAN RAFFAELE, INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE, ASSISTANCE PUBLIQUE HOPITAUX DE PARIS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE, SORBONNE UNIVERSITE, WESTFÄLISCHE WILHELMS-UNIVERSITÄT MÜNSTER, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, HEINRICH HEINE UNIVERSITY DÜSSELDORF, UNIVERSITÄTSMEDIZIN DER JOHANNES GUTENBERG-UNIVERSITÄT MAINZ, THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIVERSITY, ISTITUTO SUPERIORE DI SANITÀ, CONSIGLIO NAZIONALE DELLE RICERCHE, IRBM S.P.A.
    Inventors: Gianvito MARTINO, Paola PANINA, Brahim NAIT-OUMESMAR, Anne BARON-VAN EVERCOOREN, Tanja KUHLMANN, Sergio BARANZINI, Norbert GOEBELS, Frauke ZIPP, Nicholas HANUSCHECK, Jack ANTEL, Cristina AGRESTI, Maria Pia ABBRACCHIO, Ivano EBERINI, Chiara PARRAVICINI, Stefania OLLA, Alberto BRESCIANI
  • GPR17 receptor modulators
    Patent number: 9879030
    Abstract: Chemical compounds are provided which act on GPR17 receptors and are useful in the treatment or amelioration of chronic and/or acute neurodegenerative diseases, such as multiple sclerosis, inflammatory diseases, pathologies involving the immune system, cardiovascular diseases, and renal diseases.
    Type: Grant
    Filed: May 9, 2012
    Date of Patent: January 30, 2018
    Assignees: UNIVERSITA′ DEGLI STUDI DI MILANO, FONDAZIONE ITALIANA SCLEROSI MULTIPLA—FISM ONLUS
    Inventors: Maria Pia Abbracchio, Mario Alberto Battaglia, Ivano Eberini, Marta Fumagalli, Chiara Parravicini, Cristina Sensi, Paola Zaratin
  • GPR17 Receptor Modulators
    Publication number: 20150141410
    Abstract: Chemical compounds are provided which act on GPR17 receptors and are useful in the treatment or amelioration of chronic and/or acute neurodegenerative diseases, such as multiple sclerosis, inflammatory diseases, pathologies involving the immune system, cardiovascular diseases, and renal diseases.
    Type: Application
    Filed: May 9, 2012
    Publication date: May 21, 2015
    Applicants: UNIVERSITA' DEGLI STUDI DI MILANO, FONDAZIONE ITALIANA SCLEROSI MULTIPLA - FISH ONLUS
    Inventors: Maria Pia Abbracchio, Mario Alberto Battaglia, Ivano Eberini, Marta Fumagalli, Chiara Parravicini, Cristina Sensi, Paola Zaratin
  • GPR17 modulators, method of screening and uses thereof
    Patent number: 8158593
    Abstract: The invention provides GPR17 modulators, methods of screening and use thereof for diagnosis and therapy of diseases or dysfunctions involving GPR17 activation, particularly ischemic brain damage.
    Type: Grant
    Filed: October 17, 2005
    Date of Patent: April 17, 2012
    Assignees: Universita' degli Studi di Milano, Universita' degli Studi di Pisa, Consiglio Nazionale delle Ricerche
    Inventors: Maria Pia Abbracchio, Paolo Ciana, Gianenrico Rovati, Claudia Martini, Maria Letizia Trincavelli, Claudia Verderio
  • Gpr17 modulators,method of screening and uses thereof
    Publication number: 20090156521
    Abstract: The invention provides GPR17 modulators, methods of screening and use thereof for diagnosis and therapy of diseases or dysfunctions involving GPR17 activation, particularly ischemic brain damage.
    Type: Application
    Filed: October 17, 2005
    Publication date: June 18, 2009
    Inventors: Maria Pia Abbracchio, Paolo Ciana, Gianenrico Rovati, Claudia Martini, Maria Letizia Trincavelli, Claudia Verderio