Patents by Inventor Maribel Lopera SIERRA

Maribel Lopera SIERRA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of Treatment of Neuroendocrine Tumors That Over-Express Somatostatatin Receptors
    Publication number: 20220143227
    Abstract: The present invention relates to methods of treating cancers that over-express somatostatin receptors. More specifically, the invention provides a combined therapy in which a combination of Peptide Receptor Radionuclide Therapy (PRRT) and Immuno Oncology therapy (I-O therapy) are administered for the treatment of neuroendocrine tumors.
    Type: Application
    Filed: January 20, 2022
    Publication date: May 12, 2022
    Inventors: Stefano Buono, Maribel Lopera Sierra
  • METHOD OF TREATMENT OF NEUROENDOCRINE TUMORS
    Publication number: 20220072166
    Abstract: The present invention relates to methods of treating cancers that overexpress somatostatin receptors, e.g. neuroendocrine tumors (NET). In particular, the invention provides novel therapies based on the combination of a peptide receptor radionuclide therapeutic (PRRT) agent and immuno-oncology (I-O) therapeutic agents, wherein said I-O therapeutic agents are selected from the group consisting of LAG-3 inhibitors, TIM-3 inhibitors, GITR angonists, TGF-? inhibitors, IL15/IL-15RA complex, and selected PD-1 inhibitors.
    Type: Application
    Filed: July 24, 2019
    Publication date: March 10, 2022
    Inventors: Stefano BUONO, Clementina BRAMBATI, Donato BARBATO, Daniela CHICCO, Francesco DE PALO, Lorenza FUGAZZA, Maribel LOPERA-SIERRA, Maurizio MARIANI, Giovanni TESORIERE
  • Method of Treatment of Neuroendocrine Tumors That Over-Express Somatostatatin Receptors
    Publication number: 20180185524
    Abstract: The present invention relates to methods of treating cancers that over-express somatostatin receptors. More specifically, the invention provides a combined therapy in which a combination of Peptide Receptor Radionuclide Therapy (PRRT) and Immuno Oncology therapy (I-O therapy) are administered for the treatment of neuroendocrine tumors.
    Type: Application
    Filed: June 24, 2016
    Publication date: July 5, 2018
    Inventors: Stefano BUONO, Maribel Lopera SIERRA