Patents by Inventor Marie-Anne Euzen

Marie-Anne Euzen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11684791
    Abstract: An active implantable medical device includes a detection electrode and a pulse generator. The pulse generator is configured to collect via the detection electrode at least two EGM signals, combine the EGM signals into two time components, and combine the components into a single 2D parametric characteristic representing the cardiac cycle. During a tachyarrhythmia episode, the device measures stores values of a cycle-to-cycle variation in an amplitude of the at least one of the EGM signals, distributes the amplitude variation values into a plurality of classes, each class corresponding to an amplitude interval, and analyzes a size of each of the plurality of classes to deliver at least one of an indicator of suspicion of an artifact of extracardiac origin or an indicator of a type of tachyarrhythmia selectively as a function of at least one predetermined criterion applied to the distribution of the amplitude variation values.
    Type: Grant
    Filed: October 26, 2020
    Date of Patent: June 27, 2023
    Assignee: Sorin CRM SAS
    Inventors: Marie-Anne Euzen, Paola Milpied
  • Patent number: 11198009
    Abstract: According to some embodiments, a device operates by comparative morphological analysis of depolarization signals collected in spontaneous rhythm on separate respective channels, with two temporal components combined into a single 2D parametric VGM vectogram characteristic. Similarity quantification methods evaluate a variation over time of a descriptor parameter of a current VGM compared to a stored previous reference VGM. This variation is compared with predetermined thresholds to diagnose an occurrence of remodeling or reverse remodeling in a patient, and/or to detect a lead failure or an occurrence of ischemia. The descriptor parameter is a function of a velocity vector of the VGM, a comparison relating to a correlation coefficient between respective magnitudes of a current VGM velocity vector and of a reference VGM velocity vector, and an average angle between these respective velocity vectors.
    Type: Grant
    Filed: September 19, 2019
    Date of Patent: December 14, 2021
    Assignee: Sorin CRM SAS
    Inventors: Paola Milpied, Marie-Anne Euzen
  • Patent number: 11058881
    Abstract: The disclosure relates to a device including a plurality of electrodes for stimulation of both ventricles with application of an atrioventricular delay and of an interventricular delay, a processor configured to multidimensionally measure an interventricular conduction delay, and monitor the evolution of a patient's condition. For the multidimensional measurement of the interventricular conduction delay, the device produces stimulation of one of the ventricles and collects, in the other ventricle, two endocardial electrogram signals on separate respective channels, giving two respective temporal components. Both temporal components are combined in one single parametric 2D characteristic representative of the cardiac cycle, and a comparison is made with reference descriptors for deriving an index representative of the evolution of the patient's condition.
    Type: Grant
    Filed: June 21, 2019
    Date of Patent: July 13, 2021
    Assignee: Sorin CRM SAS
    Inventors: Marie-Anne Euzen, Paola Milpied
  • Publication number: 20210106840
    Abstract: An active implantable medical device includes a detection electrode and a pulse generator. The pulse generator is configured to collect via the detection electrode at least two EGM signals, combine the EGM signals into two time components, and combine the components into a single 2D parametric characteristic representing the cardiac cycle. During a tachyarrhythmia episode, the device measures stores values of a cycle-to-cycle variation in an amplitude of the at least one of the EGM signals, distributes the amplitude variation values into a plurality of classes, each class corresponding to an amplitude interval, and analyzes a size of each of the plurality of classes to deliver at least one of an indicator of suspicion of an artifact of extracardiac origin or an indicator of a type of tachyarrhythmia selectively as a function of at least one predetermined criterion applied to the distribution of the amplitude variation values.
    Type: Application
    Filed: October 26, 2020
    Publication date: April 15, 2021
    Inventors: Marie-Anne Euzen, Paola Milpied
  • Patent number: 10814138
    Abstract: This disclosure relates to active implantable medical devices. Some such devices include a pulse generator and at least one detection electrode. A processor of the pulse generator is configured to collect via the detection electrode at least two EGM signals, combine the EGM signals into two time components, and combine the components into a single 2D parametric characteristic representing the cardiac cycle. During a tachyarrhythmia episode, the device stores the consecutive values of the cycle-to-cycle variation in the amplitude of one EGM signal, distributes same into a plurality of classes each corresponding to an amplitude interval, and performs a statistical analysis of the totals for each class so as to output, selectively, on the basis of at least one predetermined criterion applied to the distribution of the amplitude variations into the various classes, an indicator of a suspected extracardiac artifact or an indicator of tachyarrhythmia.
    Type: Grant
    Filed: January 9, 2017
    Date of Patent: October 27, 2020
    Assignee: Sorin CRM SAS
    Inventors: Marie-Anne Euzen, Paola Milpied
  • Publication number: 20200009382
    Abstract: According to some embodiments, a device operates by comparative morphological analysis of depolarization signals collected in spontaneous rhythm on separate respective channels, with two temporal components combined into a single 2D parametric VGM vectogram characteristic. Similarity quantification methods evaluate a variation over time of a descriptor parameter of a current VGM compared to a stored previous reference VGM. This variation is compared with predetermined thresholds to diagnose an occurrence of remodeling or reverse remodeling in a patient, and/or to detect a lead failure or an occurrence of ischemia. The descriptor parameter is a function of a velocity vector of the VGM, a comparison relating to a correlation coefficient between respective magnitudes of a current VGM velocity vector and of a reference VGM velocity vector, and an average angle between these respective velocity vectors.
    Type: Application
    Filed: September 19, 2019
    Publication date: January 9, 2020
    Applicant: SORIN CRM SAS
    Inventors: Paola Milpied, Marie-Anne Euzen
  • Publication number: 20200009389
    Abstract: The disclosure relates to a device including a plurality of electrodes for stimulation of both ventricles with application of an atrioventricular delay and of an interventricular delay, a processor configured to multidimensionally measure an interventricular conduction delay, and monitor the evolution of a patient's condition. For the multidimensional measurement of the interventricular conduction delay, the device produces stimulation of one of the ventricles and collects, in the other ventricle, two endocardial electrogram signals on separate respective channels, giving two respective temporal components. Both temporal components are combined in one single parametric 2D characteristic representative of the cardiac cycle, and a comparison is made with reference descriptors for deriving an index representative of the evolution of the patient's condition.
    Type: Application
    Filed: June 21, 2019
    Publication date: January 9, 2020
    Applicant: SORIN CRM SAS
    Inventors: Marie-Anne Euzen, Paola Milpied
  • Patent number: 10420945
    Abstract: According to some embodiments, a device operates by comparative morphological analysis of depolarization signals collected in spontaneous rhythm on separate respective channels, with two temporal components combined into a single 2D parametric VGM vectogram characteristic. Similarity quantification methods evaluate a variation over time of a descriptor parameter of a current VGM compared to a stored previous reference VGM. This variation is compared with predetermined thresholds to diagnose an occurrence of remodeling or reverse remodeling in a patient, and/or to detect a lead failure or an occurrence of ischemia. The descriptor parameter is a function of a velocity vector of the VGM, a comparison relating to a correlation coefficient between respective magnitudes of a current VGM velocity vector and of a reference VGM velocity vector, and an average angle between these respective velocity vectors.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: September 24, 2019
    Assignee: Sorin CRM SAS
    Inventors: Paola Milpied, Marie-Anne Euzen
  • Patent number: 10328269
    Abstract: The disclosure relates to a device including a plurality of electrodes for stimulation of both ventricles with application of an atrioventricular delay and of an interventricular delay, a processor configured to multidimensionally measure an interventricular conduction delay, and monitor the evolution of a patient's condition. For the multidimensional measurement of the interventricular conduction delay, the device produces stimulation of one of the ventricles and collects, in the other ventricle, two endocardial electrogram signals on separate respective channels, giving two respective temporal components. Both temporal components are combined in one single parametric 2D characteristic representative of the cardiac cycle, and a comparison is made with reference descriptors for deriving an index representative of the evolution of the patient's condition.
    Type: Grant
    Filed: July 12, 2018
    Date of Patent: June 25, 2019
    Assignee: Sorin CRM SAS
    Inventors: Marie-Anne Euzen, Paola Milpied
  • Publication number: 20190117990
    Abstract: This disclosure relates to active implantable medical devices. Some such devices include a pulse generator and at least one detection electrode. A processor of the pulse generator is configured to collect via the detection electrode at least two EGM signals, combine the EGM signals into two time components, and combine the components into a single 2D parametric characteristic representing the cardiac cycle. During a tachyarrhythmia episode, the device stores the consecutive values of the cycle-to-cycle variation in the amplitude of one EGM signal, distributes same into a plurality of classes each corresponding to an amplitude interval, and performs a statistical analysis of the totals for each class so as to output, selectively, on the basis of at least one predetermined criterion applied to the distribution of the amplitude variations into the various classes, an indicator of a suspected extracardiac artifact or an indicator of tachyarrhythmia.
    Type: Application
    Filed: January 9, 2017
    Publication date: April 25, 2019
    Inventors: Marie-Anne Euzen, Paola Milpied
  • Publication number: 20180326216
    Abstract: The disclosure relates to a device including a plurality of electrodes for stimulation of both ventricles with application of an atrioventricular delay and of an interventricular delay, a processor configured to multidimensionally measure an interventricular conduction delay, and monitor the evolution of a patient's condition. For the multidimensional measurement of the interventricular conduction delay, the device produces stimulation of one of the ventricles and collects, in the other ventricle, two endocardial electrogram signals on separate respective channels, giving two respective temporal components. Both temporal components are combined in one single parametric 2D characteristic representative of the cardiac cycle, and a comparison is made with reference descriptors for deriving an index representative of the evolution of the patient's condition.
    Type: Application
    Filed: July 12, 2018
    Publication date: November 15, 2018
    Applicant: SORIN CRM SAS
    Inventors: Marie-Anne Euzen, Paola Milpied
  • Patent number: 10022547
    Abstract: The disclosure relates to a device including a plurality of electrodes for stimulation of both ventricles with application of an atrioventricular delay and of an interventricular delay, a processor configured to multidimensionally measure an interventricular conduction delay, and monitor the evolution of a patient's condition. For the multidimensional measurement of the interventricular conduction delay, the device produces stimulation of one of the ventricles and collects, in the other ventricle, two endocardial electrogram signals on separate respective channels, giving two respective temporal components. Both temporal components are combined in one single parametric 2D characteristic representative of the cardiac cycle, and a comparison is made with reference descriptors for deriving an index representative of the evolution of the patient's condition.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: July 17, 2018
    Assignee: Sorin CRM SAS
    Inventors: Marie-Anne Euzen, Paola Milpied
  • Publication number: 20170368349
    Abstract: According to some embodiments, a device operates by comparative morphological analysis of depolarization signals collected in spontaneous rhythm on separate respective channels, with two temporal components combined into a single 2D parametric VGM vectogram characteristic. Similarity quantification methods evaluate a variation over time of a descriptor parameter of a current VGM compared to a stored previous reference VGM. This variation is compared with predetermined thresholds to diagnose an occurrence of remodeling or reverse remodeling in a patient, and/or to detect a lead failure or an occurrence of ischemia. The descriptor parameter is a function of a velocity vector of the VGM, a comparison relating to a correlation coefficient between respective magnitudes of a current VGM velocity vector and of a reference VGM velocity vector, and an average angle between these respective velocity vectors.
    Type: Application
    Filed: September 11, 2017
    Publication date: December 28, 2017
    Applicant: SORIN CRM SAS
    Inventors: Paola Milpied, Marie-Anne Euzen
  • Publication number: 20170368353
    Abstract: The disclosure relates to a device including a plurality of electrodes for stimulation of both ventricles with application of an atrioventricular delay and of an interventricular delay, a processor configured to multidimensionally measure an interventricular conduction delay, and monitor the evolution of a patient's condition. For the multidimensional measurement of the interventricular conduction delay, the device produces stimulation of one of the ventricles and collects, in the other ventricle, two endocardial electrogram signals on separate respective channels, giving two respective temporal components. Both temporal components are combined in one single parametric 2D characteristic representative of the cardiac cycle, and a comparison is made with reference descriptors for deriving an index representative of the evolution of the patient's condition.
    Type: Application
    Filed: September 11, 2017
    Publication date: December 28, 2017
    Applicant: SORIN CRM SAS
    Inventors: Marie-Anne Euzen, Paola Milpied
  • Patent number: 9757568
    Abstract: The disclosure relates to a device including a plurality of electrodes for stimulation of both ventricles with application of an atrioventricular delay and of an interventricular delay, a processor configured to multidimensionally measure an interventricular conduction delay, and monitor the evolution of a patient's condition. For the multidimensional measurement of the interventricular conduction delay, the device produces stimulation of one of the ventricles and collects, in the other ventricle, two endocardial electrogram signals on separate respective channels, giving two respective temporal components. Both temporal components are combined in one single parametric 2D characteristic representative of the cardiac cycle, and a comparison is made with reference descriptors for deriving an index representative of the evolution of the patient's condition.
    Type: Grant
    Filed: March 31, 2016
    Date of Patent: September 12, 2017
    Assignee: SORIN CRM SAS
    Inventors: Marie-Anne Euzen, Paola Milpied
  • Patent number: 9757566
    Abstract: According to some embodiments, a device operates by comparative morphological analysis of depolarization signals collected in spontaneous rhythm on separate respective channels, with two temporal components combined into a single 2D parametric VGM vectogram characteristic. Similarity quantification methods evaluate a variation over time of a descriptor parameter of a current VGM compared to a stored previous reference VGM. This variation is compared with predetermined thresholds to diagnose an occurrence of remodeling or reverse remodeling in a patient, and/or to detect a lead failure or an occurrence of ischemia. The descriptor parameter is a function of a velocity vector of the VGM, a comparison relating to a correlation coefficient between respective magnitudes of a current VGM velocity vector and of a reference VGM velocity vector, and an average angle between these respective velocity vectors.
    Type: Grant
    Filed: April 15, 2016
    Date of Patent: September 12, 2017
    Assignee: SORIN CRM SAS
    Inventors: Paola Milpied, Marie-Anne Euzen
  • Publication number: 20160303372
    Abstract: According to some embodiments, a device operates by comparative morphological analysis of depolarization signals collected in spontaneous rhythm on separate respective channels, with two temporal components combined into a single 2D parametric VGM vectogram characteristic. Similarity quantification methods evaluate a variation over time of a descriptor parameter of a current VGM compared to a stored previous reference VGM. This variation is compared with predetermined thresholds to diagnose an occurrence of remodeling or reverse remodeling in a patient, and/or to detect a lead failure or an occurrence of ischemia. The descriptor parameter is a function of a velocity vector of the VGM, a comparison relating to a correlation coefficient between respective magnitudes of a current VGM velocity vector and of a reference VGM velocity vector, and an average angle between these respective velocity vectors.
    Type: Application
    Filed: April 15, 2016
    Publication date: October 20, 2016
    Inventors: Paola Milpied, Marie-Anne Euzen
  • Publication number: 20160287876
    Abstract: The disclosure relates to a device including a plurality of electrodes for stimulation of both ventricles with application of an atrioventricular delay and of an interventricular delay, a processor configured to multidimensionally measure an interventricular conduction delay, and monitor the evolution of a patient's condition. For the multidimensional measurement of the interventricular conduction delay, the device produces stimulation of one of the ventricles and collects, in the other ventricle, two endocardial electrogram signals on separate respective channels, giving two respective temporal components. Both temporal components are combined in one single parametric 2D characteristic representative of the cardiac cycle, and a comparison is made with reference descriptors for deriving an index representative of the evolution of the patient's condition.
    Type: Application
    Filed: March 31, 2016
    Publication date: October 6, 2016
    Inventors: Marie-Anne Euzen, Paola Milpied
  • Patent number: 9014805
    Abstract: A device produces at least two distinct temporal components (Vbip, Vuni) from two separate endocardial electrogram (EGM) signals concurrently collected. The capture test determines a non-temporal 2D characteristic (VGM) representative of the cardiac cycle to be analyzed. The VGM is constructed using variations of one of the temporal components (Vuni) according to the other (Vbip). The devices determines the presence or absence of capture by analysis of this characteristic relative to a two dimensional domain.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: April 21, 2015
    Assignee: Sorin CRM S.A.S.
    Inventors: Marie-Anne Euzen, Elodie Vincent
  • Patent number: 8874212
    Abstract: A device produces at least two distinct temporal components (Vbip, Vuni) from two separate endocardial electrogram EGM signals concurrently collected in the same cavity. A 2D non-temporal characteristic is determined from the variations of one of the temporal components (Vuni) versus the other (Vbip). The analysis of this characteristic allows detection of the possible presence of an anodal stimulation, causing a depolarization in a second cavity after stimulation delivered to a first heart chamber, opposite to the first. One possibility is to proceed by observing whether the non-temporal 2D characteristic is included or not within a predetermined domain defined in a coordinate frame corresponding to the space of the two temporal components.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: October 28, 2014
    Assignee: Sorin CRM S.A.S.
    Inventors: Marie-Anne Euzen, Elodie Vincent, Laurence Graindorge