Patent number: 6451789
Abstract: Compound of formula (I):
wherein:
n represents 0 or 1,
R1 represents hydrogen, arylalkyl, alkyl, acyl, alkoxycarbonyl, arylalkoxycarbonyl or trifluoroacetyl,
R2 represents alkyl,
X represents oxygen, chlorine, OR3, SR4 or NOR5,
R3 represents hydrogen , alkyl, acyl, alkoxycarbonyl or arylalkoxycarbonyl,
R4 represents hydrogen, alkyl or aryl,
R5 represents hydrogen or optionally substituted alkyl,
represents a single or double bond,
Ar represents aryl or heteroaryl, its isomers and addition salts thereof with a pharmaceutically acceptable acid, and medicinal products containing the same which are useful as facilitators of memory and cognition and antalgic agents.
Type:
Grant
Filed:
September 26, 2001
Date of Patent:
September 17, 2002
Assignee:
Les Labortoires Servier
Inventors:
Sylvain Rault, Olivier Renault, Jean Guillon, Patrick Dallemagne, Pierre Renard, Bruno Pfeiffer, Pierre Lestage, Marie-Cécile Lebrun