Patents by Inventor Marie-Céline FRANTZ

Marie-Céline FRANTZ has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230144767
    Abstract: Provided herein are compositions and related methods useful for free radical scavenging, with particular selectivity for mitochondria. The compounds comprise a nitroxide-containing group attached to a mitochondria-targeting group. The compounds can be cross-linked into dimers without loss of activity. Also provided herein are methods, for preventing, mitigating and treating damage caused by radiation. The method comprises delivering a compound, as described herein, to a patient in an amount and dosage regimen effective to prevent, mitigate or treat damage caused by radiation.
    Type: Application
    Filed: January 5, 2023
    Publication date: May 11, 2023
    Applicant: University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: Peter Wipf, Marie-Celine Frantz
  • Patent number: 11420960
    Abstract: The present invention relates to the cosmetic use, as moisturizer for keratin materials, preferably the skin, of one or more 5-oxazolidine-2,4-dione C-glycoside derivatives corresponding to formula (I) below, and also the solvates and/or the isomers (optical, geometric, tautomers) thereof and/or the salts thereof: (I)
    Type: Grant
    Filed: June 19, 2019
    Date of Patent: August 23, 2022
    Assignee: L'OREAL
    Inventors: Maria Dalko, Amélie Prevot-Gueguiniat, Marie-céline Frantz, Sébastien Dropsit
  • Patent number: 11364189
    Abstract: The present invention relates to a method for the cosmetic treatment of keratin materials, comprising the application of a composition to the keratin materials, such as the skin, said composition comprising a compound (I), wherein R1, R2 and R3 are as defined in the description and S* is a mono or polysaccharide.
    Type: Grant
    Filed: November 7, 2017
    Date of Patent: June 21, 2022
    Assignee: L'OREAL
    Inventor: Marie-céline Frantz
  • Publication number: 20210371460
    Abstract: Provided herein are compositions and related methods useful for free radical scavenging, with particular selectivity for mitochondria. The compounds comprise a nitroxide-containing group attached to a mitochondria-targeting group. The compounds can be cross-linked into dimers without loss of activity. Also provided herein are methods, for preventing, mitigating and treating damage caused by radiation. The method comprises delivering a compound, as described herein, to a patient in an amount and dosage regimen effective to prevent, mitigate or treat damage caused by radiation.
    Type: Application
    Filed: January 14, 2021
    Publication date: December 2, 2021
    Applicant: University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: Peter Wipf, Marie-Celine Frantz
  • Publication number: 20210276989
    Abstract: The present invention relates to the cosmetic use, as moisturizer for keratin materials, preferably the skin, of one or more 5-oxazolidine-2,4-dione C-glycoside derivatives corresponding to formula (I) below, and also the solvates and/or the isomers (optical, geometric, tautomers) thereof and/or the salts thereof: (I)
    Type: Application
    Filed: June 19, 2019
    Publication date: September 9, 2021
    Inventors: Maria DALKO, Amélie PREVOT-GUEGUINIAT, Marie-Céline FRANTZ, Sébastien DROPSIT
  • Patent number: 11045411
    Abstract: The present invention relates to a process for cosmetic treatment of the skin, comprising the application to the skin of a composition comprising a compound (I) with R, R? and X as defined in the description and S* a monosaccharide or polysaccharide.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: June 29, 2021
    Assignee: L'OREAL
    Inventors: Maria Dalko, Marie-céline Frantz, Amélie Gueguiniat, Jinzhu Xu, Lisheng Mao
  • Publication number: 20200317730
    Abstract: Provided herein are compositions and related methods useful for free radical scavenging, with particular selectivity for mitochondria. The compounds comprise a nitroxide-containing group attached to a mitochondria-targeting group. The compounds can be cross-linked into dimers without loss of activity. Also provided herein are methods, for preventing, mitigating and treating damage caused by radiation. The method comprises delivering a compound, as described herein, to a patient in an amount and dosage regimen effective to prevent, mitigate or treat damage caused by radiation.
    Type: Application
    Filed: November 20, 2019
    Publication date: October 8, 2020
    Applicant: University of Pittsburgh - Of the Commonwealth System of Higher Education
    Inventors: Peter Wipf, Marie-Celine Frantz
  • Patent number: 10526368
    Abstract: Provided herein are compositions and related methods useful for free radical scavenging, with particular selectivity for mitochondria. The compounds comprise a nitroxide-containing group attached to a mitochondria-targeting group. The compounds can be cross-linked into dimers without loss of activity. Also provided herein are methods, for preventing, mitigating and treating damage caused by radiation. The method comprises delivering a compound, as described herein, to a patient in an amount and dosage regimen effective to prevent, mitigate or treat damage caused by radiation.
    Type: Grant
    Filed: December 27, 2017
    Date of Patent: January 7, 2020
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Peter Wipf, Marie-Celine Frantz
  • Publication number: 20190274940
    Abstract: The present invention relates to a method for the cosmetic treatment of keratin materials, comprising the application of a composition to the keratin materials, such as the skin, said composition comprising a compound (I), wherein R1, R2 and R3 are as defined in the description and S* is a mono or polysaccharide.
    Type: Application
    Filed: November 7, 2017
    Publication date: September 12, 2019
    Inventor: Marie-céline FRANTZ
  • Publication number: 20190263770
    Abstract: The present invention relates to a method for the cosmetic treatment of keratin materials, in particular the skin, comprising the application of a composition to the keratin materials, such as the skin, said composition comprising a compound (I), wherein R is as defined in the description and S* is a mono or polysaccharide. In particular, the invention relates to the non-therapeutic cosmetic use of at least one compound of formula (I) as an agent for whitening, lightening and/or depigmenting keratin materials, such as the skin.
    Type: Application
    Filed: November 7, 2017
    Publication date: August 29, 2019
    Inventors: Marie-céline FRANTZ, Maria DALKO
  • Patent number: 10357440
    Abstract: The present invention relates to the cosmetic use, in a composition containing a physiologically acceptable medium, of at least one compound of formula (I) in which: —R3 means a hydrogen atom or a hydroxyl radical, —R1 and R2 mean, independently of each other, a hydrogen atom, a linear or branched C1-C6 alkyl radical; a benzyl radical; a linear or branched C1-C6 alkylcarbonyl radical not conjugated with the carbonyl; or a linear or branched C1-C6 alkoxycarbonyl radical, and/or of an isomer and/or of a salt and/or of a solvate of said compound of formula (1), for preventing and/or treating the signs of ageing of the skin and its appendages.
    Type: Grant
    Filed: December 21, 2015
    Date of Patent: July 23, 2019
    Assignee: L'OREAL
    Inventors: Julien Hitce, Maria Dalko, Marie-Céline Frantz
  • Publication number: 20180298054
    Abstract: Provided herein are compositions and related methods useful for free radical scavenging, with particular selectivity for mitochondria. The compounds comprise a nitroxide-containing group attached to a mitochondria-targeting group. The compounds can be cross-linked into dimers without loss of activity. Also provided herein are methods, for preventing, mitigating and treating damage caused by radiation. The method comprises delivering a compound, as described herein, to a patient in an amount and dosage regimen effective to prevent, mitigate or treat damage caused by radiation.
    Type: Application
    Filed: December 27, 2017
    Publication date: October 18, 2018
    Applicant: University of Pittsburgh - Of the Commonwealth Sys tem of Higher Education
    Inventors: Peter Wipf, Marie-Celine Frantz
  • Publication number: 20180133137
    Abstract: The present invention relates to a process for cosmetic treatment of the skin, comprising the application to the skin of a composition comprising a compound (I) with R, R? and X as defined in the description and S* a monosaccharide or polysaccharide.
    Type: Application
    Filed: May 9, 2016
    Publication date: May 17, 2018
    Inventors: Maria DALKO, Marie-Céline FRANTZ, Emélie GUEGUINIAT, Jinzhu XU, Lisheng MAO
  • Patent number: 9890192
    Abstract: Provided herein are compositions and related methods useful for free radical scavenging, with particular selectivity for mitochondria. The compounds comprise a nitroxide-containing group attached to a mitochondria-targeting group. The compounds can be cross-linked into dimers without loss of activity. Also provided herein are methods, for preventing, mitigating and treating damage caused by radiation. The method comprises delivering a compound, as described herein, to a patient in an amount and dosage regimen effective to prevent, mitigate or treat damage caused by radiation.
    Type: Grant
    Filed: November 17, 2015
    Date of Patent: February 13, 2018
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Peter Wipf, Marie-Celine Frantz
  • Publication number: 20170367952
    Abstract: The present invention relates to the cosmetic use, in a composition containing a physiologically acceptable medium, of at least one compound of formula (I) in which: —R3 means a hydrogen atom or a hydroxyl radical, —R1 and R2 mean, independently of each other, a hydrogen atom, a linear or branched C1-C6 alkyl radical; a benzyl radical; a linear or branched C1-C6 alkylcarbonyl radical not conjugated with the carbonyl; or a linear or branched C1-C6 alkoxycarbonyl radical, and/or of an isomer and/or of a salt and/or of a solvate of said compound of formula (1), for preventing and/or treating the signs of ageing of the skin and its appendages.
    Type: Application
    Filed: December 21, 2015
    Publication date: December 28, 2017
    Applicant: L'OREAL
    Inventors: Julien HITCE, Maria DALKO, Marie-Céline FRANTZ
  • Patent number: 9732105
    Abstract: A compound having a structure of:
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: August 15, 2017
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Peter Wipf, Marie-Celine Frantz
  • Publication number: 20160137692
    Abstract: Provided herein are compositions and related methods useful for free radical scavenging, with particular selectivity for mitochondria. The compounds comprise a nitroxide-containing group attached to a mitochondria-targeting group. The compounds can be cross-linked into dimers without loss of activity. Also provided herein are methods, for preventing, mitigating and treating damage caused by radiation. The method comprises delivering a compound, as described herein, to a patient in an amount and dosage regimen effective to prevent, mitigate or treat damage caused by radiation.
    Type: Application
    Filed: November 17, 2015
    Publication date: May 19, 2016
    Applicant: University of Pittsburgh - of the Commonwealth System of Higher Education
    Inventors: Peter Wipf, Marie-Celine Frantz
  • Publication number: 20160068556
    Abstract: A compound having a structure of:
    Type: Application
    Filed: November 13, 2015
    Publication date: March 10, 2016
    Applicant: University of Pittsburgh - of the Commonwealth System of Higher Education
    Inventors: Peter Wipf, Marie-Celine Frantz
  • Patent number: 9216976
    Abstract: Provided herein are compositions and related methods useful for free radical scavenging, with particular selectivity for mitochondria. The compounds comprise a nitroxide-containing group attached to a mitochondria-targeting group. The compounds can be cross-linked into dimers without loss of activity. Also provided herein are methods, for preventing, mitigating and treating damage caused by radiation. The method comprises delivering a compound, as described herein, to a patient in an amount and dosage regimen effective to prevent, mitigate or treat damage caused by radiation.
    Type: Grant
    Filed: November 22, 2013
    Date of Patent: December 22, 2015
    Assignee: University of Pittsburgh—of the Commonwealth System of Higher Education
    Inventors: Peter Wipf, Marie-Celine Frantz
  • Patent number: 9217000
    Abstract: A compound having a structure of:
    Type: Grant
    Filed: February 17, 2012
    Date of Patent: December 22, 2015
    Assignee: Univerisyt of Pittsburgh—of the Commonwealth System of Higher Education
    Inventors: Peter Wipf, Marie-Celine Frantz