Patents by Inventor Marie-Claude Viaud

Marie-Claude Viaud has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190365914
    Abstract: Disclosed are novel antibody-drug conjugates and use thereof in therapy, in particular in anticancer or anti-inflammatory therapy, as well as synthetic products useful as linkers, composed of a linker head and a linker body, and also a method for preparing the linkers and the antibody-drug conjugates.
    Type: Application
    Filed: April 11, 2019
    Publication date: December 5, 2019
    Inventors: Nicolas JOUBERT, Marie Claude VIAUD-MASSUARD, Renaud RESPAUD
  • Patent number: 10307488
    Abstract: Disclosed are novel antibody-drug conjugates and use thereof in therapy, in particular in anticancer or anti-inflammatory therapy, as well as synthetic products useful as linkers, composed of a linker head and a linker body, and also a method for preparing the linkers and the antibody-drug conjugates.
    Type: Grant
    Filed: July 11, 2014
    Date of Patent: June 4, 2019
    Assignee: UNIVERSITE FRANCOIS RABELAIS
    Inventors: Nicolas Joubert, Marie Claude Viaud-Massuard, Renaud Respaud
  • Patent number: 9427719
    Abstract: A method is provided for encapsulating products that can have lipophilic or hydrophilic, including volatile, properties in a polysiloxane membrane that is particularly impervious. A method is also provided for evaluating the imperviousness of capsules. The present method includes the following steps: a) formation of droplets by an emulsion between an oily phase containing the product to be encapsulated and an acidic aqueous phase heated to around 50° C. and in the presence of surfactants; b) addition and hydrolysis of at least one silane in order to obtain a silanol; c) increasing the pH in order to start condensation of the silanol to form a first membrane around the droplets of the product to be encapsulated; d) lowering the pH; e) increasing the pH, optionally preceded by adding a silane, in order to obtain a new condensation of silanol around the droplets of the product to be encapsulated.
    Type: Grant
    Filed: September 22, 2011
    Date of Patent: August 30, 2016
    Assignee: UNIVERSITE DE TOURS FRANCOIS RABELAIS
    Inventors: Marie-Claude Viaud-Massuard, Jeremy Monfray, Peggy Robert, Elodie Raynaud, Vincent Bouazza
  • Publication number: 20160151515
    Abstract: Disclosed are novel antibody-drug conjugates and use thereof in therapy, in particular in anticancer or anti-inflammatory therapy, as well as synthetic products useful as linkers, composed of a linker head and a linker body, and also a method for preparing the linkers and the antibody-drug conjugates.
    Type: Application
    Filed: July 11, 2014
    Publication date: June 2, 2016
    Inventors: Nicolas JOUBERT, Marie Claude VIAUD-MASSUARD, Renaud RESPAUD
  • Publication number: 20130181363
    Abstract: A method is provided for encapsulating products that can have lipophilic or hydrophilic, including volatile, properties in a polysiloxane membrane that is particularly impervious. A method is also provided for evaluating the imperviousness of capsules. The present method includes the following steps: a) formation of droplets by an emulsion between an oily phase containing the product to be encapsulated and an acidic aqueous phase heated to around 50° C. and in the presence of surfactants; b) addition and hydrolysis of at least one silane in order to obtain a silanol; c) increasing the pH in order to start condensation of the silanol to form a first membrane around the droplets of the product to be encapsulated; d) lowering the pH; e) increasing the pH, optionally preceded by adding a silane, in order to obtain a new condensation of silanol around the droplets of the product to be encapsulated.
    Type: Application
    Filed: September 22, 2011
    Publication date: July 18, 2013
    Applicant: UNIVERSITE DE TOURS FRANCOIS RABELAIS
    Inventors: Marie-Claude Viaud-Massuard, Jeremy Monfray, Peggy Robert, Elodie Raynaud, Vincent Bouazza
  • Publication number: 20110124703
    Abstract: The invention concerns molecules with a bis-(heteroaryl)maleimide structure and having inhibiting characteristics with respect to enzymes with a catalytic pocket comprising the invariant amino acids D, D and E or D, D and D, such as transposases, RAG recombinases or retroviral integrases. The invention also concerns the use of said molecules for in vitro, ex vivo or in vivo inhibition of transposases, RAG recombinases and retroviral integrases such as HIV integrase, as well as the use of said molecules in the treatment of diseases associated with these enzymes in an animal or human host, in particular in the treatment of AIDS.
    Type: Application
    Filed: February 3, 2009
    Publication date: May 26, 2011
    Inventors: Marie-Claude Viaud-Massuard, Jérôme Guillard, Yves Bigot, Corinne Auge-Gouillou
  • Publication number: 20090124656
    Abstract: Compounds of formula (I): wherein: R1, R2, R3, R4 and X are as defined in the description, A represents an alkylene chain as defined in the description, B represents an alkyl or alkenyl group substituted by a group or R7, or B represents a group or R7. Medicinal products containing the same which are useful as hypoglycaemic and hypolipaemic agents.
    Type: Application
    Filed: January 26, 2006
    Publication date: May 14, 2009
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Cicile Parmenon, Marie-Claude Viaud-Massuard, Jerome Guillard, Catherine Dacuet, Alain Ktorza, Daniel- Henri Caignard
  • Patent number: 7235550
    Abstract: The invention relates to compounds of formula (I): wherein: G1 represents an alkylene chain as defined in the description, A represents R2 and R3 represent hydrogen, alkyl, alkoxy or hydroxy or together form oxo, R4 and R5 represent hydrogen, R1 is as defined in the description, and medicinal products containing the same which are useful in treating or preventing melatoninergic disorders.
    Type: Grant
    Filed: October 9, 2002
    Date of Patent: June 26, 2007
    Assignee: Les Laboratoires Servier
    Inventors: Gérald Guillaumet, Marie-Claude Viaud, Hervé Van de Poel, Philippe Delagrange, Caroline Bennejean, Pierre Renard
  • Publication number: 20070123529
    Abstract: The invention relates to compound of formula (I) wherein: B represents hydrogen, COOR, CONRR?, or (C1-C6)alkyl substituted by COOR, CONRR?, or OR, G1 represents —X?—(CH2)n—X—(CH2)m—X?— chain wherein X, X?, X?, n and m are as defined in the description, Cy represents a grouping of formula (II) or (III): G2 represents alkylene chain as defined in the description, and A represents NRCOR?, NRCSR?, CONRR?, CSNRR?, NRCONR?R?, or NRCSNR?R?. and medicinal products containing the same which are useful in treating or preventing melatoninergic disorders.
    Type: Application
    Filed: December 18, 2006
    Publication date: May 31, 2007
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Carole Descamps-Francois, Said Yous, Daniel Lesieur, Gerald Guillaumet, Marie-Claude Viaud, Herve Da-Costa, Caroline Bennejean, Philippe Delagrange, Pierre Renard
  • Patent number: 7183318
    Abstract: The invention concerns compounds of formula (1): R-A-R? wherein: A is as defined in the description; R represent a group (V), (VI), (VII), or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R? represents a —(CH2)t—R5 group wherein t and R5 are as defined in the description, and medicaments containing the same
    Type: Grant
    Filed: June 16, 2003
    Date of Patent: February 27, 2007
    Assignee: Les Laboratoires Servier
    Inventors: Daniel Lesieur, Frederique Klupsch, Gerald Guillaumet, Marie-Claude Viaud, Michel Langlois, Caroline Bennejean, Pierre Renard, Philippe Delagrange
  • Patent number: 7161035
    Abstract: The invention relates to compounds of formula (I): wherein: B represents a hydrogen atom, a COOR group, a CONRR? group, or a (C1–C6)alkyl group substituted by a COOR, CONRR? or OR group, G1 represents a —X?—(CH2)n—X—(CH2)m—X?— chain wherein X, X?, X?, n and m are as defined in the description, Cy represents a grouping of formula (II) or (III): G2 represents an alkylene chain as defined in the description, and A represents a NRCOR?, NRCSR?, CONRR?, CSNRR?, NRCONR?R? or NRCSNR?R? group.
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: January 9, 2007
    Assignee: Les Laboratoires Servier
    Inventors: Carole Descamps-Francois, Said Yous, Daniel Lesieur, Gérald Guillaumet, Marie-Claude Viaud, Hervé Da Costa, Caroline Bennejean, Philippe Delagrange, Pierre Renard
  • Patent number: 7126012
    Abstract: The invention concerns compounds of formula (I): R-A-R? wherein: A is as defined in the description; R represents a group (V), (VI), (VII) or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R? represents a —(CH2)t-R5 group wherein t and R5 are as defined in the description
    Type: Grant
    Filed: September 23, 2004
    Date of Patent: October 24, 2006
    Assignee: Les Laboratoires Servier
    Inventors: Daniel Lesieur, Frederique Klupsch, Gerald Guillaumet, Marie-Claude Viaud, Michel Langlois, Caroline Bennejean, Pierre Renaud, Philippe Delagrange
  • Patent number: 7115752
    Abstract: The invention concerns compounds of formula (I): R—A—R? wherein: A is as defined in the description; R represents a group (V), (VI), (VII) or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R? represents a —(CH2)t-R5 group wherein t and R5 are as defined in the description.
    Type: Grant
    Filed: September 23, 2004
    Date of Patent: October 3, 2006
    Assignee: Les Laboratoires Servier
    Inventors: Daniel Lesieur, Frederique Klupsch, Gerald Guillaumet, Marie-Claude Viaud, Michel Langlois, Caroline Bennejean, Pierre Renaud, Philippe Delagrange
  • Publication number: 20050124682
    Abstract: The invention concerns compounds of formula (I): R-A-R? wherein: A is as defined in the description; R represents a group (V), (VI), (VII) or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R? represents a —(CH2)t-R5 group wherein t and R5 are as defined in the description.
    Type: Application
    Filed: September 23, 2004
    Publication date: June 9, 2005
    Inventors: Daniel Lesieur, Frederique Klupsch, Gerald Guillaumet, Marie-Claude Viaud, Michel Langlois, Caroline Bennejean, Pierre Renard, Philippe Delagrange
  • Patent number: 6872851
    Abstract: The invention concerns compounds of formula (I): R—A—R? wherein: A is as defined in the description; R represent, a group (V), wherein R?a and R?a are as defined in the description, or R forms with A a cyclic structure as defined in the description; R? represents a (CH2)t—R2 group wherein q, t, and R2 are as defined in the description. The invention is useful for preparing medicines.
    Type: Grant
    Filed: May 10, 1999
    Date of Patent: March 29, 2005
    Assignee: Les Laboratories Servier
    Inventors: Daniel Lesieur, Frédérique Klupsch, Gérald Guillaumet, Marie-Claude Viaud, Michel Langlois, Caroline Bennejean, Pierre Renard, Philippe Delagrange
  • Publication number: 20050059729
    Abstract: The invention concerns compounds of formula (I): R-A-R? wherein: A is as defined in the description; R represents a group (V), (VI), (VII) or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R? represents a —(CH2)t-R5 group wherein t and R5 are as defined in the description.
    Type: Application
    Filed: September 23, 2004
    Publication date: March 17, 2005
    Inventors: Daniel Lesieur, Frederique Klupsch, Gerald Guillaumet, Marie-Claude Viaud, Michel Langlois, Caroline Bennejean, Pierre Renard, Philippe Delagrange
  • Publication number: 20040014969
    Abstract: The invention relates to compound of formula (I): 1
    Type: Application
    Filed: March 14, 2003
    Publication date: January 22, 2004
    Inventors: Carole Descamps-Francois, Said Yous, Daniel Lesieur, Gerald Guillaumet, Marie-Claude Viaud, Herve Da Costa, Caroline Bennejean, Philippe Delagranes, Pierre Renard
  • Publication number: 20040002490
    Abstract: The invention concerns compounds of formula (I): R-A-R′ wherein: A is as defined in the description; R represent a group (V), (VI), (VII), or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R′ represents a —(CH2)t—R5 group wherein t and R5 are as defined in the description, and medicaments containing the same.
    Type: Application
    Filed: June 16, 2003
    Publication date: January 1, 2004
    Inventors: Daniel Lesieur, Frederique Klupsch, Gerald Guillaumet, Marie-Claude Viaud, Michel Langlois, Caroline Bennejean, Pierre Renard, Philippe Delagrange
  • Publication number: 20040002491
    Abstract: The invention concerns compounds of formula (1): R-A-R′ wherein: A is as defined in the description; R represent a group (V), (VI), (VII), or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R′ represents a —(CH2)t—R5 group wherein t and R5 are as defined in the description, and medicaments containing the same.
    Type: Application
    Filed: June 16, 2003
    Publication date: January 1, 2004
    Inventors: Daniel Lesieur, Frederique Klupsch, Gerald Guillaumet, Marie-Claude Viaud, Michel Langlois, Caroline Bennejean, Pierre Renard, Philippe Delagrange
  • Patent number: 6667304
    Abstract: The invention relates to compound of formula (I): wherein: G1 represents an alkylene chain as defined in the description, A represents R2 and R3 represent hydrogen, alkyl, alkoxy or hydroxy or together form oxo, R4 and R5 represent hydrogen, R1 is as defined in the description, and medicinal products containing the same which are useful in treating or preventing melatoninergic disorders.
    Type: Grant
    Filed: October 9, 2002
    Date of Patent: December 23, 2003
    Assignee: Les Laboratoires Servier
    Inventors: Gérald Guillaumet, Marie-Claude Viaud, Hervé Van De Poel, Philippe Delagrange, Caroline Bennejean, Pierre Renard