Patents by Inventor Marie Flamand

Marie Flamand has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • A NOVEL COMPLEX FORMED BETWEEN THE FLAVIVIRAL NON-STRUCTURAL NS1 PROTEIN AND PLASMA LIPOPROTEINS
    Publication number: 20220341933
    Abstract: The invention concerns methods for early detection, monitoring and prognosis of a flavivirus-induced infection, comprising the detection of a complex formed by the flavivirus non-structural glycoprotein NS1 and plasma lipoprotein particles in a biological anti-NS1 Mab sample during the clinical phase of the infection.
    Type: Application
    Filed: September 25, 2020
    Publication date: October 27, 2022
    Inventors: Marie FLAMAND, Kyu-Ho Paul PARK, Souheyla BENFRID, Carole TAMIETTI, James VOSS, Fasseli COULIBALY, Veasna DUONG, Philippe DUSSART, Anavaj SAKUNTABHAI, Quentin GIAI GIANETTO, Mariette MATONDO, Mariano DELLAROLE, Francois BONTEMS, Felix REY
  • Neurovirulent strain of the West Nile virus and uses thereof
    Patent number: 9657276
    Abstract: Neuroinvasive and neurovirulent strain of the West Nile virus, named IS-98-ST1, nucleic acid molecules derived from its genome, proteins and peptides encoded by said nucleic acid molecules, and uses thereof.
    Type: Grant
    Filed: March 31, 2014
    Date of Patent: May 23, 2017
    Assignees: Institut Pasteur, Kimron Veterinary Institute
    Inventors: Despres Philippe, Vincent Deubel, Jean-Louis Guenet, Marie-Therese Drouet, Mertyn Malkinson, Caroline Banet, Marie-Pascale Frenkiel, Marie-Pierre Courageot, Fasseli Coulibaly, Adeline Catteau, Marie Flamand, Patrick Weber, Pierre-Emmanuel Ceccaldi
  • Neurovirulent Strain of the West Nile Virus and Uses Thereof
    Publication number: 20140237631
    Abstract: Neuroinvasive and neurovirulent strain of the West Nile virus, named IS-98-ST1, nucleic acid molecules derived from its genome, proteins and peptides encoded by said nucleic acid molecules, and uses thereof.
    Type: Application
    Filed: March 31, 2014
    Publication date: August 21, 2014
    Applicants: KIMRON VETERINARY INSTITUTE, INSTITUT PASTEUR
    Inventors: Despres Philippe, Vincent Deubel, Jean-Louis Guenet, Marie-Therese Drouet, Mertyn Malkinson, Caroline Banet, Marie-Pascale Frenkiel, Marie-Pierre Courageot, Fasseli Coulibaly, Adeline Catteau, Marie Flamand, Patrick Weber, Pierre-Emmanuel Ceccaldi
  • Neurovirulent strain of the West Nile virus and uses thereof
    Patent number: 8715693
    Abstract: Neuroinvasive and neurovirulent strain of the West Nile virus, named IS-98-ST1, nucleic acid molecules derived from its genome, proteins and peptides encoded by said nucleic acid molecules, and uses thereof.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: May 6, 2014
    Assignees: Institut Pasteur, Kimron Veterinary Institute
    Inventors: Philippe Despres, Vincent Deubel, Jean-Louis Guenet, Marie-Thérèse Drouet, Mertyn Malkinson, Caroline Banet, Marie-Pascale Frenkiel, Marie-Pierre Courageot, Fasséli Coulibaly, Adeline Catteau, Marie Flamand, Patrick Weber, Pierre-Emmanuel Ceccaldi
  • Assay for the diagnosis of flaviviral infection using antibodies with high affinity for NS1 protein of flavivirusi in hexameric form
    Patent number: 8709427
    Abstract: The invention concerns a method for early detection of a flavivirus-induced infection, comprising the detection of the flavivirus non-structural glycoprotein NS1 in a biological sample during the clinical phase of the infection, by an immunological method using at least two identical or different antibodies, the first antibody consisting of polyclonal or monoclonal antibodies pre-selected for their high affinity for said NS1 protein hexameric in shape.
    Type: Grant
    Filed: July 26, 2011
    Date of Patent: April 29, 2014
    Assignee: Institut Pasteur
    Inventors: Marie Flamand, Françoise Megret, Sophie Alcon, Antoine Talarmin, Philippe Despres, Vincent Deubel
  • NEUROVIRULENT STRAIN OF THE WEST NILE VIRUS AND USES THEREOF
    Publication number: 20120266261
    Abstract: Neuroinvasive and neurovirulent strain of the West Nile virus, named IS-98-ST1, nucleic acid molecules derived from its genome, proteins and peptides encoded by said nucleic acid molecules, and uses thereof.
    Type: Application
    Filed: March 16, 2012
    Publication date: October 18, 2012
    Inventors: Philippe Despres, Vincent Deubel, Jean-Louis Guenet, Marie-Thérèse Drouet, Mertyn Malkinson, Caroline Banet, Marie-Pascale Frenkiel, Marie-Pierre Courageot, Fasséli Coulibaly, Adeline Catteau, Marie Flamand, Patrick Weber, Pierre-Emmanuel Ceccaldi
  • EARLY DETECTION OF FLAVIVIRUSES USING THE NS1 GLYCOPROTEIN
    Publication number: 20120009216
    Abstract: The invention concerns a method for early detection of a flavivirus-induced infection, comprising the detection of the flavivirus non-structural glycoprotein NS1 in a biological sample during the clinical phase of the infection, by an immunological method using at least two identical or different antibodies, the first antibody consisting of polyclonal or monoclonal antibodies pre-selected for their high affinity for said NS1 protein hexameric in shape.
    Type: Application
    Filed: July 26, 2011
    Publication date: January 12, 2012
    Inventors: Marie Flamand, Françoise Megret, Sophie Alcon, Antoine Talarmin, Philippe Despres, Vincent Deubel
  • NEUROVIRULENT STRAIN OF THE WEST NILE VIRUS AND USES THEREOF
    Publication number: 20100099854
    Abstract: Neuroinvasive and neurovirulent strain of the West Nile virus, named IS-98-ST1, nucleic acid molecules derived from its genome, proteins and peptides encoded by said nucleic acid molecules, and uses thereof.
    Type: Application
    Filed: April 30, 2008
    Publication date: April 22, 2010
    Applicants: INSTITUT PASTEUR, KIMRON VETERINARY INSTITUTE
    Inventors: PHILIPPE DESPRES, VINCENT DEUBEL, JEAN-LOUIS GUENET, MARIE-THERESE DROUET, MERTYN MALKINSON, CAROLINE BANET, MARIE-PASCALE FRENKIEL, MARIE-PIERRE COURAGEOT, FASSELI COULIBALY, ADELINE CATTEAU, MARIE FLAMAND, PATRICK WEBER, PIERRE-EMMANUEL CECCALDI
  • Early detection of flaviviruses using the NS1 glycoprotein
    Patent number: 7670766
    Abstract: The invention concerns a method for early detection of a flavivirus-induced infection, comprising the detection of the flavivirus non-structural glycoprotein NS1 in a biological sample during the clinical phase of the infection, by an immunological method using at least two identical or different antibodies, the first antibody consisting of polyclonal or monoclonal antibodies pre-selected for their high affinity for said NS1 protein hexameric in shape.
    Type: Grant
    Filed: September 11, 2007
    Date of Patent: March 2, 2010
    Assignee: Institut Pasteur
    Inventors: Marie Flamand, Françoise Megret, Sophie Alcon, Antoine Talarmin, Philippe Despres, Vincent Deubel
  • NONSTRUCTURAL PROTEIN NS1 AS A NOVEL THERAPEUTIC TARGET AGAINST FLAVIVIRUSES
    Publication number: 20090275499
    Abstract: The secretion or biological activity of Flaviviruses, as well as the biological activity of NS1 protein from Flavivirus-infected cells, can be inhibited by contacting the cells or the protein with cholesterol inhibitors, sphingolipid inhibitors, glycosphingolipid inhibitors, or molecules comprising an amphipathic, amphiphilic, or hydrophobic region which interacts with NS1 protein.
    Type: Application
    Filed: February 26, 2009
    Publication date: November 5, 2009
    Inventors: Marie Flamand, Jerome Salmon, Felix Rey, Irina Gutsche, Myriam Ermonval, Samer Kayal
  • Early detection of flaviviruses using the NS1 glycoprotein
    Publication number: 20090226478
    Abstract: The invention concerns a method for early detection of a flavivirus-induced infection, comprising the detection of the flavivirus non-structural glycoprotein NS1 in a biological sample during the clinical phase of the infection, by an immunological method using at least two identical or different antibodies, the first antibody consisting of polyclonal or monoclonal antibodies pre-selected for their high affinity for said NS1 protein hexameric in shape.
    Type: Application
    Filed: August 21, 2007
    Publication date: September 10, 2009
    Inventors: Marie Flamand, Francoise Megret, Sophie Alcon, Antoine Talarmin, Philippe Despres, Vincent Deubel
  • Early detection of flaviviruses using the NS1 glycoprotein
    Publication number: 20090068213
    Abstract: The invention concerns a method for early detection of a flavivirus-induced infection, comprising the detection of the flavivirus non-structural glycoprotein NS1 in a biological sample during the clinical phase of the infection, by an immunological method using at least two identical or different antibodies, the first antibody consisting of polyclonal or monoclonal antibodies pre-selected for their high affinity for said NS1 protein hexameric in shape.
    Type: Application
    Filed: September 11, 2007
    Publication date: March 12, 2009
    Inventors: Marie Flamand, Francoise Megret, Sophie Alcon, Antoine Talarmin, Phillippe Despres, Vincent Deubel
  • Neurovirulent strain of the West Nile virus and uses thereof
    Patent number: 7390495
    Abstract: Neuroinvasive and neurovirulent strain of the West Nile virus, named IS-98-ST1, nucleic acid molecules derived from its genome, proteins and peptides encoded by said nucleic acid molecules, and uses thereof.
    Type: Grant
    Filed: October 4, 2004
    Date of Patent: June 24, 2008
    Assignees: Institut Pasteur, Kimron Veterinary Institute
    Inventors: Philippe Despres, Vincent Deubel, Jean-Louis Guenet, Marie-Therese Drouet, Mertyn Malkinson, Caroline Banet, Marie-Pascale Frenkiel, Marie-Pierre Courageot, Fasseli Coulibaly, Adeline Catteau, Marie Flamand, Patrick Weber, Pierre-Emmanuel Ceccaldi
  • Assay for the diagnosis of flaviviral infection using antibodies with high affinity for NS1 protein of flavivirus in hexameric form
    Patent number: 7282341
    Abstract: The invention concerns a method for early detection of a flavivirus-induced infection, comprising the detection of the flavivirus non-structural glycoprotein NS1 in a biological sample during the clinical phase of the infection, by an immumological method using at least two identical or different antibodies, the first antibody consisting of polyclonal or monoclonal antibodies pre-selected for their high affinity for said NS1 protein hexameric in shape.
    Type: Grant
    Filed: December 21, 2004
    Date of Patent: October 16, 2007
    Assignee: Institut Pasteur
    Inventors: Marie Flamand, Françoise Megret, Sophie Alcon, Antoine Talarmin, Philippe Despres, Vincent Deubel
  • Assay for the diagnosis of flaviviral infection using antibodies with high affinity for NS1 protein of flavivirus in hexameric form
    Publication number: 20050186562
    Abstract: The invention concerns a method for early detection of a flavivirus-induced infection, comprising the detection of the flavivirus non-structural glycoprotein NS1 in a biological sample during the clinical phase of the infection, by an immumological method using at least two identical or different antibodies, the first antibody consisting of polyclonal or monoclonal antibodies pre-selected for their high affinity for said NS1 protein hexameric in shape.
    Type: Application
    Filed: December 21, 2004
    Publication date: August 25, 2005
    Inventors: Marie Flamand, Francoise Megret, Sophie Alcon, Antoine Talarmin, Philippe Despres, Vincent Deubel
  • Neurovirulent strain of the west nile virus and uses thereof
    Publication number: 20050164170
    Abstract: Neuroinvasive and neurovirulent strain of the West Nile virus, named IS-98-ST1, nucleic acid molecules derived from its genome, proteins and peptides encoded by said nucleic acid molecules, and uses thereof.
    Type: Application
    Filed: October 4, 2004
    Publication date: July 28, 2005
    Applicants: INSTITUT PASTEUR, KIMRON VETERINARY INSTITUTE
    Inventors: Philippe Despres, Vincent Deubel, Jean-Louis Guenet, Marie-Therese Drouet, Mertyn Malkinson, Caroline Banet, Marie-Pascale Frenkiel, Marie-Pierre Courageot, Fasseli Coulibaly, Adeline Catteau, Marie Flamand, Patrick Weber, Pierre-Emmanuel Ceccaldi
  • Assay for the diagnosis of flaviviral infection using antibodies with high affinity for NS1 protein of flavivirus in hexameric form
    Patent number: 6870032
    Abstract: The invention concerns a method for early detection of a flavivirus-induced infection, comprising the detection of the flavivirus non-structural glycoprotein NS1 in a biological sample during the clinical phase of the infection, by an immunological method using at least two identical or different antibodies, the first antibody consisting of polyclonal or monoclonal antibodies pre-selected for their high affinity for said NS1 protein hexameric in shape.
    Type: Grant
    Filed: June 9, 2000
    Date of Patent: March 22, 2005
    Assignee: Institut Pasteur
    Inventors: Marie Flamand, Françoise Megret, Sophie Alcon, Antoine Talarmin, Philippe Despres, Vincent Deubel