Patents by Inventor Marie-France Eauclaire

Marie-France Eauclaire has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Surface plasmon resonance approach to monitor protein-ligand interactions
    Patent number: 10429300
    Abstract: The present invention provides assays utilizing SPR to detect protein-ligand interactions as well as compositions utilized is such assays.
    Type: Grant
    Filed: January 26, 2016
    Date of Patent: October 1, 2019
    Assignees: The Johns Hopkins University, Le Centre National de la Recherche Scientifique, Aix-Marseilles University
    Inventors: Frank Bosmans, Pierre E. Bougis, Marie-France Eauclaire
  • Scorpion peptide as hypotensive agent
    Patent number: 7192925
    Abstract: The present invention provides isoformes from a peptide family belonging to South American scorpion Tityus serrulatus that acts as hypotensive agents by potentiating Bradykinin and, therefore, can be used as anti-hypertensive drugs. A peptide was firstly isolated from Tityus serrulatus venom and showed a strong and long-lasted hypotensive activity when tested in rats. This peptide was first named TsHpt-I (Tityus serrulatus Hypotensin-I). Also, three more highly similar isoformes were identified and revealed a peptide family with very close primary structure. They were named TsHpt-II, TsHpt-III and TsHpt-IV.
    Type: Grant
    Filed: June 9, 2003
    Date of Patent: March 20, 2007
    Assignee: Universidade Federal de Minas Gerais
    Inventors: Maria Elena de Lima Perez-Garcia, Carlos Ribeiro Diniz, Robson Augusto Souza Dos Santos, Pierre Edouard Bougis, Marie-France Eauclaire, Adriano Monteiro de Castro Pimenta
  • Scorpion peptide as hypotensive agent
    Publication number: 20060014928
    Abstract: The present invention provides isoformes from a peptide family belonging to South American scorpion Tityus serrulatus that acts as hypotensive agents by potentiating Bradykinin and, therefore, can be used as anti-hypertensive drugs. A peptide was firstly isolated from Tityus serrulatus venom and showed a strong and long-lasted hypotensive activity when tested in rats. This peptide was first named TsHpt-I (Tityus serrulatus Hypotensin-I). Also, three more highly similar isoformes were identified and revealed a peptide family with very close primary structure. They were named TsHpt-II, TsHpt-III and TsHpt-IV.
    Type: Application
    Filed: June 9, 2003
    Publication date: January 19, 2006
    Applicant: UNIVERSIDADE FEDERAL DE MINAS GERAIS
    Inventors: Maria Elena de Lima Perez-Garcia, Carlos Ribeiro, Robson Dos Santos, Pierre Bougis, Marie-France Eauclaire, Adriano Pimenta