Abstract: The invention provides a compound of formula (I): or a prodrug thereof, or a pharmaceutically acceptable salt thereof, wherein R1 and R2 have any of the values described in the specification, as well as compositions comprising a compound of formula (I) or a prodrug thereof, or a pharmaceutically acceptable salt thereof. The compounds are agonists of glycolytic enzyme phosphofructokinase-1 liver type and are useful for treating diseases associated with the activity of glycolytic enzyme phosphofructokinase-1 liver type, such as cancer, diabetes, sepsis, and septic shock.

Abstract: The disclosed systems can regulate access to an online mode for a dynamic transportation matching system. For example, based on a provider efficiency parameter associated with the dynamic transportation matching system, the disclosed systems can prevent a transportation provider device from switching to the online mode within a geographic area. In addition, the disclosed systems can detect a pattern of behavior and, based on a comparison between the pattern of behavior and a behavioral threshold, cause a transportation provider device to switch from the online mode to an offline mode. Further, the disclosed systems can provide a map interface that indicates where a transportation provider device can switch from the offline mode to the online mode. Additionally, the disclosed systems can determine priorities associated with transportation provider devices and, based on the prioritization, selectively allow the transportation provider devices to switch from the offline mode to the online mode.

Abstract: A trailer for towing a watersport vehicle that includes a depth sensor. The depth sensor can detect when the trailer is within a suitable depth of water to launch and/or retrieve the watersport vehicle. The trailer can include one or more sensors to assist in positioning the watersport vehicle on the trailer. Use of the trailer can enable a user to efficiently and properly load and unload the watersport vehicle onto and from the trailer.

Abstract: A foil displacement system includes one or more foils that can be deployed and stowed. When deployed, each foil can exert downforce or uplift depending on its orientation. For example, each foil may be positioned to have an angle of attack that creates a downward force effectively transmitted to the hull to pull the hull deeper within the water to, for example, create a larger wake. Use of the foil displacement system can enhance or replace the use of a ballast tank system, can be integrated into a new boat or retrofitted to existing boats, can be electronically or manually positioned, can enhance activities such as wake surfing, wake boarding, water skiing or other similar or related water sports.

Abstract: An adjustable surf wake system enhances a wake formed by a watercraft travelling through water. The system may include a flap for deflecting water traveling past the stern of the watercraft, and/or a positioner operably connected to the flap for positioning the flap relative to a longitudinal axis of the watercraft between a neutral position and an outward position. Positioning a port flap in its extended position enhances a starboard surf wake, and positioning the starboard flap in its extended position enhances a port surf wake.

Abstract: A foil displacement system includes one or more foils that can be deployed and stowed. When deployed, each foil can exert downforce or uplift depending on its orientation. For example, each foil may be positioned to have an angle of attack that creates a downward force effectively transmitted to the hull to pull the hull deeper within the water to, for example, create a larger wake. Use of the foil displacement system can enhance or replace the use of a ballast tank system, can be integrated into a new boat or retrofitted to existing boats, can be electronically or manually positioned, can enhance activities such as wake surfing, wake boarding, water skiing or other similar or related water sports.

Abstract: An adjustable surf wake system enhances a wake formed by a watercraft travelling through water. The system may include a flap for deflecting water traveling past the stern of the watercraft, and/or a positioner operably connected to the flap for positioning the flap relative to a longitudinal axis of the watercraft between a neutral position and an outward position. Positioning a port flap in its extended position enhances a starboard surf wake, and positioning the starboard flap in its extended position enhances a port surf wake.

Abstract: A foil displacement system includes one or more foils that can be deployed and stowed. When deployed, each foil can exert downforce or uplift depending on its orientation. For example, each foil may be positioned to have an angle of attack that creates a downward force effectively transmitted to the hull to pull the hull deeper within the water to, for example, create a larger wake. Use of the foil displacement system can enhance or replace the use of a ballast tank system, can be integrated into a new boat or retrofitted to existing boats, can be electronically or manually positioned, can enhance activities such as wake surfing, wake boarding, water skiing or other similar or related water sports.

Abstract: An adjustable surf wake system enhances a wake formed by a watercraft travelling through water. The system may include a flap for deflecting water traveling past the stern of the watercraft, and/or a positioner operably connected to the flap for positioning the flap relative to a longitudinal axis of the watercraft between a neutral position and an outward position. Positioning a port flap in its extended position enhances a starboard surf wake, and positioning the starboard flap in its extended position enhances a port surf wake.

Abstract: A foil displacement system includes one or more foils that can be deployed and stowed. When deployed, each foil can exert downforce or uplift depending on its orientation. For example, each foil may be positioned to have an angle of attack that creates a downward force effectively transmitted to the hull to pull the hull deeper within the water to, for example, create a larger wake. Use of the foil displacement system can enhance or replace the use of a ballast tank system, can be integrated into a new boat or retrofitted to existing boats, can be electronically or manually positioned, can enhance activities such as wake surfing, wake boarding, water skiing or other similar or related water sports.

Abstract: A foil displacement system includes one or more foils that can be deployed and stowed. When deployed, each foil can exert downforce or uplift depending on its orientation. For example, each foil may be positioned to have an angle of attack that creates a downward force effectively transmitted to the hull to pull the hull deeper within the water to, for example, create a larger wake. Use of the foil displacement system can enhance or replace the use of a ballast tank system, can be integrated into a new boat or retrofitted to existing boats, can be electronically or manually positioned, can enhance activities such as wake surfing, wake boarding, water skiing or other similar or related water sports.

Abstract: An adjustable surf wake system can enhance a wake formed by a watercraft travelling through water. A rider control device can enable a rider to control the wake of the watercraft while riding the wake, such as for wake surfing. The rider can adjust the speed of the watercraft, can adjust the height of the wake, and/or can change the watercraft between a surf-left configuration and a surf-right configuration. The rider control device can include a position sensor. A drone can position a camera based on the position sensor of the rider control device for filming the rider.

Abstract: An adjustable surf wake system can enhance a wake formed by a watercraft travelling through water. A rider control device can enable a rider to control the wake of the watercraft while riding the wake, such as for wake surfing. The rider can adjust the speed of the watercraft, can adjust the height of the wake, and/or can change the watercraft between a surf-left configuration and a surf-right configuration. The rider control device can include a position sensor. A drone can position a camera based on the position sensor of the rider control device for filming the rider.

Abstract: An adjustable surf wake system enhances a wake formed by a watercraft travelling through water. The system may include a flap for deflecting water traveling past the stern of the watercraft, and/or a positioner operably connected to the flap for positioning the flap relative to a longitudinal axis of the watercraft between a neutral position and an outward position. Positioning a port flap in its extended position enhances a starboard surf wake, and positioning the starboard flap in its extended position enhances a port surf wake.

Abstract: A lid for a beverage container can include a cover member configured to releasably engage the opening of a beverage container. The cover member can include an aroma aperture defined through a portion thereof, the aroma aperture sized and shaped to receive the nose of a user when the lid is engaged with the opening of the beverage container and the user drinks a beverage contained in the beverage container through the lid.

Abstract: The present disclosure provides a dance training vest and method for dance training. The dance training vest includes a first band cuff operably engaged with the vest, a second band cuff operably engaged with the vest, and a plurality of force simulating members operably engaged with the vest, the first band cuff, and the second band cuff. The plurality of force simulating members is positioned in a desired location to assist with the simulation of proper user position during a dance movement. The method for dance training includes donning, by a user, a first dance training vest, connecting a first end of a first force simulating member to the first training vest, moving in a dance movement to move the first dance training vest, and imparting a force of the first force simulating member to the first training vest.

Abstract: A lid for a beverage cup includes a mouth opening, an aroma opening, and a concentrator member. The mouth opening is positioned closer to a rim of the lid than the aroma opening. An area of the aroma opening is greater than an area of the mouth opening. The concentrator member surrounds the aroma opening and extends from a plane formed by the aroma opening to a height above the aroma opening. A cross sectional area of the concentrator decreases in a direction from a base to an upper end of the concentrator, creating a concentration of beverage aromas in the space surrounding a user's nose. The concentrator channels a concentrated amount of aroma to the nose, providing an enhanced drinking and tasting experience.

Abstract: An adjustable surf wake system enhances a wake formed by a watercraft travelling through water. The system may include a flap for deflecting water traveling past the stern of the watercraft, and/or a positioner operably connected to the flap for positioning the flap relative to a longitudinal axis of the watercraft between a neutral position and an outward position. Positioning a port flap in its extended position enhances a starboard surf wake, and positioning the starboard flap in its extended position enhances a port surf wake.

Abstract: An adjustable surf wake system can enhance a wake formed by a watercraft travelling through water. A rider control device can enable a rider to control the wake of the watercraft while riding the wake, such as for wake surfing. The rider can adjust the speed of the watercraft, can adjust the height of the wake, and/or can change the watercraft between a surf-left configuration and a surf-right configuration. The rider control device can include a position sensor. A drone can position a camera based on the position sensor of the rider control device for filming the rider.

Abstract: An adjustable surf wake system can enhance a wake formed by a watercraft travelling through water. A rider control device can enable a rider to control the wake of the watercraft while riding the wake, such as for wake surfing. The rider can adjust the speed of the watercraft, can adjust the height of the wake, and/or can change the watercraft between a surf-left configuration and a surf-right configuration. The rider control device can include a position sensor. A drone can position a camera based on the position sensor of the rider control device for filming the rider.