Abstract: The invention pertains to an ophthalmological device (100, 200) for the treatment of Limbal Stem Cell Deficiency, the device (100, 200) comprising: a stem cell carrier substrate; and a culture of limbal epithelial stem cells cultivated on said stem cell carrier substrate; wherein said stem cell carrier substrate comprises a hydrogel containing collagen or collagen-mimicking peptides; and wherein a ring-shaped area on a surface of said stem cell carrier substrate is provided with a pattern of niches (110, 210). The invention also pertains to a method for producing the ophthalmological device.

Abstract: A composition includes particles for use in a method for the treatment of a vitreous disease or a vitreous disorder as a light sensitizing agent. Each particle has a surface selected for or adapted for providing mobility of the particle in the vitreous and for binding to collagen aggregates, such as floaters.

Abstract: This invention describes an intraocular lens (IOL) design with a removable optic, which can be inserted in and removed from a haptic device. In this haptic the anterior and posterior capsules are sealed in order to have a perfect control over the lens epithelial cell proliferation which is thereby restricted to the peripheral part of the capsular bag. Additionally, a ring caliper is described as new surgical device to allow a precise sizing and centration of the anterior capsulorhexis. The removable optic allows repeatable correction of the eye focusing over time in case the optical parameters of the eye have changed due to a variety of factors. By separating the optic part from the haptic part, the optic part can easily be manufactured in any shape matching the optical errors of the eye, including the optical aberrations. The optic part can be manufactured out of any biomaterial restoring ocular accommodation.

Abstract: This invention describes a simple intraocular lens (IOL) design with a removable optic, which can be inserted in and removed from a haptic device. In this haptic the anterior and posterior capsules are sealed in order to have a perfect control over the lens epithelial cell proliferation which is thereby restricted to the peripheral part of the capsular bag. Additionally, a ring caliper is described as new surgical device to allow a precise sizing and centration of the anterior capsulorhexis. The removable optic allows repeatable correction of the eye focusing over time in case the optical parameters of the eye have changed due to a variety of factors. By separating the optic part from the haptic part, the optic part can easily be manufactured in any shape matching the optical errors of the eye, including the ocular aberrations. The optic part can be manufactured out of any biomaterial restoring ocular accommodation.