Patents by Inventor Marie-Louise Hendrickx

Marie-Louise Hendrickx has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • (2-morpholinylmethyl) benzamide derivatives
    Patent number: 6100262
    Abstract: The present invention concerns novel (2-morpholinylmethyl)benzamide derivatives having the formula ##STR1## the N-oxide forms, the pharmaceutically acceptable addition salts and the stereochemically isomeric forms thereof, wherein R.sup.1 is C.sub.1-6 alkyl, C.sub.2-6 alkenyl or C.sub.2-6 alkynyl; R.sup.2 is hydrogen, halo or C.sub.1-6 alkylsulfonylamino; R.sup.3 is hydrogen or C.sub.1-6 alkyl; L is a radical of formula R.sup.4 --C(.dbd.O)--Alk-- (a); R.sup.5 --C(.dbd.O)--N(R.sup.6)--Alk-- (b); or R.sup.7 --C(.dbd.O)--O--Alk-- (c); wherein each Alk is independently C.sub.1-12 alkanediyl; R.sup.4 is hydrogen, hydroxy, C.sub.1-6 alkyl, C.sub.1-6 alkyloxy, amino, mono- or di(C.sub.1-6 alkyl)amino or an optionally substituted heterocyclic ring; R.sup.5 and R.sup.7 each independently are hydrogen, C.sub.1-6 alkyl, C.sub.1-6 alkyloxy, amino, mono- or di(C.sub.1-6 alkyl)amino or an optionally substituted heterocyclic ring; R.sup.6 is hydrogen or C.sub.
    Type: Grant
    Filed: September 22, 1999
    Date of Patent: August 8, 2000
    Assignee: Janssen Pharmaceutica, NV.
    Inventors: Marie-Louise Hendrickx, Kurt Godfried Cornelius Emile Van Daele, Peter Jules Victor Van Daele, Glenn Kurt Ludo Van Daele, Frans Maria Alfons Van den Keybus, Marc Gustaaf Celine Verdonck
  • Enterokinetic benzamide
    Patent number: 5948794
    Abstract: The present invention is concerned with a novel benzamide derivative for formula (I). ##STR1## Pharmaceutical compositions comprising said novel compounds, processes for preparing compounds and compositions, and the use thereof as a medicine, in particular in the treatment of conditions involving a decreased motility of the intestine are described.
    Type: Grant
    Filed: September 24, 1998
    Date of Patent: September 7, 1999
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Georges H. P. Van Daele, deceased, Marie-Louise Hendrickx, heir, Kurt Godfried Cornelius Emile Van Daele, heir, Peter Jules Victor Van Daele, heir, Glenn Kurt Ludo Van Daele, heir, Jean-Paul Rene Marie Andre Bosmans, Joannes Adrianus Jacobus Schuurkes
  • Phenyl-oxo-alkyl-(4-piperidinyl)benzoate derivatives
    Patent number: 5872131
    Abstract: The present invention is concerned with novel benzoate derivatives having the formula ##STR1## the N-oxide forms, the pharmaceutically acceptable acid addition salts and the stereochemically isomeric forms thereof, wherein R.sup.1 is halo or C.sub.1-6 alkylsulfonylamino; either R.sup.2 is hydrogen and R.sup.3 is C.sub.1-6 alkyl, C.sub.2-6 alkenyl or C.sub.2-6 alkynyl; or R.sup.2 and R.sup.3 taken together form a bivalent radical of formula --CH.dbd.CH-- (a), --(CH.sub.2).sub.2 -- (b), or --(CH.sub.2).sub.3 -- (c); in the bivalent radicals of formula (a), (b) or (c) one or two hydrogen atoms may be replaced by C.sub.1-6 alkyl; Alk is C.sub.1-6 alkanediyl; R.sup.4 is hydrogen or C.sub.1-6 alkyloxy; R.sup.5, R.sup.6 and R.sup.7 each independently are hydrogen, halo, C.sub.1-6 alkyl, C.sub.1-6 alkyloxy; or R.sup.5 and R.sup.6 taken together may also form a bivalent radical of formula: --NR.sup.8 C(O)NR.sup.9 --, --NH--C(NHR.sup.10).dbd.N--, --O--(CH.sub.2).sub.m --O--; R.sup.8 and R.sup.
    Type: Grant
    Filed: March 24, 1997
    Date of Patent: February 16, 1999
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Marie-Louise Hendrickx, Kurt Godfried Cornelius Emile Van Daele, Peter Jules Victor Van Daele, Glenn Kurt Ludo Van Daele, Jean-Paul Rene Marie Andre Bosmans, Marc Gustaaf Celine Verdonck