Patents by Inventor Marie Michel
Marie Michel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240077857Abstract: Method for checking the compliance of a workpiece, comprising the following steps: estimating a risk of non-compliance of characteristic on the basis of a law of probability associated with the characteristic; and verifying whether the estimated risk of non-compliance satisfies a decision criterion and, if so, declaring that the workpiece is compliant for characteristic; if not, measuring a value of the characteristic, determining whether or not the workpiece is compliant based on the measured value, and updating the law of probability associated with characteristic based on the measured value.Type: ApplicationFiled: October 7, 2020Publication date: March 7, 2024Applicants: SAFRAN AIRCRAFT ENGINES, SAFRANInventors: Augustin Marie Michel DESCOQS, Julien Alexis Louis RICORDEAU, Quentin SULLI
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Patent number: 11912645Abstract: The invention is based on the discovery of a new bacterial compound with analgesic properties which could be used as a new tool for the treatment of pain disorders such as visceral pain. Studying the mechanisms implicated in analgesic properties of the probiotic Escherichia coli strain Nissle 1917 (EcN), inventors characterized, the amino fatty acids produced by EcN, which display the Ecn analgesic properties. One of these compounds inhibits the hypersensitivity to colorectal distension induced by capsaicin, which is a very powerful nociceptive compound and acts via the GABA B receptor. Furthermore, inventors demonstrate that this compound is able to cross the cellular epithelial barrier (such as the intestinal epithelium). Thus, the invention relates to a lipopetide compound, derived from gamma-aminobutyric acid. The invention also relates to a lipopeptide compound according to the invention for the treatment of treating pain disorder, such as somatic pain and visceral pain.Type: GrantFiled: April 27, 2018Date of Patent: February 27, 2024Assignees: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS—, ECOLE NATIONALE VETERINAIRE DE TOULOUSE, UNIVERSITE PAUL SABATIER TOULOUSE III, INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT, UNIVERSITE DE MONTPELLIER, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIERInventors: Nicolas Cenac, Justine Bertrand-Michel, Teresa Perez-Berezo, Thierry Durand, Jean-Marie Galano, Julien Pujo, Eric Oswald, Patricia Martin, Pauline Le Faouder, Alexandre Guy
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Patent number: 11867401Abstract: The invention relates to a pre-vaporizing pipe (5) for a combustion chamber of a turbomachine, comprising a generally elongate main body (50), comprising a first end portion (51) delimiting an inlet duct (52) in which a fuel injector is to be mounted, the body (50) having an external surface (500) having a first length (L1) that extends from the portion (51) to at least one first fuel outlet end piece (53), and a second length (L2) that extends the first length (L1) from the end piece (53) and that extends from the end piece (53) to a second fuel outlet end piece (54). According to the invention, inside the body (50) there is a first channel (55) connecting the duct (52) to the end piece (53) and a second channel (56) which is distinct from the first channel (55) and which connects the duct (52) to the end piece (54).Type: GrantFiled: May 25, 2020Date of Patent: January 9, 2024Assignee: SAFRAN HELICOPTER ENGINESInventors: Nicolas Roland Guy Savary, Claude Marie Michel Berat, Olivier Lamaison, Yvan Ludovic Lameignere, Hubert Pascal Verdier, Chritophe Nicolas Henri Viguier
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Publication number: 20230291552Abstract: A crypto-method of securely communicating a message; the method comprises the steps of selecting a ring R? of bi or multi variate multinomials; generating a private key which has a multinomial f; generating a public key which has a multinomial h; encrypting by representing said message as a multinomial m in R?, selecting a random multinomial r, and computing an encrypted message; and decrypting said message using said private key.Type: ApplicationFiled: July 22, 2021Publication date: September 14, 2023Inventor: Florent Christian Lucien Marie MICHEL
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Publication number: 20230188060Abstract: The device (30) for braking an electric motor comprises a rotor (54) provided with two brushes (50, 51) and a stator comprising at least two half-coils (48, 49) connected in series to the brushes while the motor is nominally activated. Said device comprises a means (30) for underpowering, e.g. freewheeling, the motor, a means (41, 42, 46) for connecting in series a single half-coil (49) to the rotor brushes and a means for controlling the braking by underpowering the motor until at least one value of a physical quantity reaches a predetermined value and the single half-coil is connected in series to the rotor brushes when the value of a physical quantity reaches the predetermined value.Type: ApplicationFiled: May 18, 2021Publication date: June 15, 2023Inventors: Yves Calange, Marie MICHEL
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Publication number: 20220235937Abstract: The invention relates to a pre-vaporizing pipe (5) for a combustion chamber of a turbomachine, comprising a generally elongate main body (50), comprising a first end portion (51) delimiting an inlet duct (52) in which a fuel injector is to be mounted, the body (50) having an external surface (500) having a first length (L1) that extends from the portion (51) to at least one first fuel outlet end piece (53), and a second length (L2) that extends the first length (L1) from the end piece (53) and that extends from the end piece (53) to a second fuel outlet end piece (54). According to the invention, inside the body (50) there is a first channel (55) connecting the duct (52) to the end piece (53) and a second channel (56) which is distinct from the first channel (55) and which connects the duct (52) to the end piece (54).Type: ApplicationFiled: May 25, 2020Publication date: July 28, 2022Applicant: SAFRAN HELICOPTER ENGINESInventors: Nicolas Roland Guy SAVARY, Claude Marie Michel BERAT, Olivier LAMAISON, Yvan Ludovic LAMEIGNERE, Hubert Pascal VERDIER, Chritophe Nicolas Henri VIGUIER
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Patent number: 10754333Abstract: A method for monitoring the operation of a turbomachine controlled by a digital control system including at least one component, includes acquiring operating state information relating to the state of at least one component; determining, depending on the state information acquired, a current degraded configuration in which at least one of the components has failed; determining a classification of the current degraded configuration using at least one classification table stored in a storage device, the classification tables associating with at least one degraded configuration one classification expressing the level of criticality of the degraded configuration, the tables being obtained by calculating a conditional probability of a predefined anticipated event from the probability of occurrence of elementary events relating to a failure of one of the components; and estimating an operating time permitted for the turbomachine depending on the classification determined for the current degraded configuration.Type: GrantFiled: December 1, 2015Date of Patent: August 25, 2020Assignee: Safran Aircraft EnginesInventors: Augustin Marie Michel Descoqs, Denis Thierry Sauvage
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Patent number: 10687125Abstract: At least one embodiment of the invention relates to a temperature and heat monitoring device comprising a housing, at least one microcontroller disposed in the housing, at least one sensor configured to determine an amount of heat adjacent to the device, at least one memory configured to store a predetermined set of values relating to heat and at least one power source in communication with the microcontroller. There is also at least one transmitter configured to communicate with an adjacent electronic device, wherein said at least one microcontroller is configured to read signals from said at least one sensor, and to determine whether the information from said sensor is outside of said predetermined set of values relating to heat and then to selectively send a signal to the adjacent electronic device to indicate a heat or temperature condition.Type: GrantFiled: January 26, 2018Date of Patent: June 16, 2020Inventor: Danielle Marie Michel
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Patent number: 10173879Abstract: The disclosure concerns a cork stopper shaving device with shaving elements fixed at predetermined angles and configured for cutting material from a cork stopper and tapering an edge thereof, such that the cork stopper, when cut, becomes modified for easy re-insertion back into a bottle or container.Type: GrantFiled: August 28, 2017Date of Patent: January 8, 2019Assignee: EYEON INNOVATIONS, LLCInventors: Anne Marie Michel, David William Reed
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Publication number: 20180220207Abstract: At least one embodiment of the invention relates to a temperature and heat monitoring device comprising a housing, at least one microcontroller disposed in the housing, at least one sensor configured to determine an amount of heat adjacent to the device, at least one memory configured to store a predetermined set of values relating to heat and at least one power source in communication with the microcontroller. There is also at least one transmitter configured to communicate with an adjacent electronic device, wherein said at least one microcontroller is configured to read signals from said at least one sensor, and to determine whether the information from said sensor is outside of said predetermined set of values relating to heat and then to selectively send a signal to the adjacent electronic device to indicate a heat or temperature condition.Type: ApplicationFiled: January 26, 2018Publication date: August 2, 2018Inventor: Danielle Marie MICHEL
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Publication number: 20170269581Abstract: A method for monitoring the operation of a turbomachine controlled by a digital control system including at least one component, includes acquiring operating state information relating to the state of at least one component; determining, depending on the state information acquired, a current degraded configuration in which at least one of the components has failed; determining a classification of the current degraded configuration using at least one classification table stored in a storage device, the classification tables associating with at least one degraded configuration one classification expressing the level of criticality of the degraded configuration, the tables being obtained by calculating a conditional probability of a predefined anticipated event from the probability of occurrence of elementary events relating to a failure of one of the components; and estimating an operating time permitted for the turbomachine depending on the classification determined for the current degraded configuration.Type: ApplicationFiled: December 1, 2015Publication date: September 21, 2017Applicant: Safran Aircraft EnginesInventors: Augustin Marie Michel DESCOQS, Denis Thierry SAUVAGE
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Publication number: 20150328645Abstract: A method for separating a suspension containing gypsum granules and calcium carbonate granules and an aqueous solution, wherein the aqueous solution comprises at least one sodium salt, wherein the aqueous solution has a sodium ion concentration of at least 3 g/L and wherein such method comprises a step of separation by flotation using a collector for the gypsum granules, the collector comprising at least one heteropolar organic surfactant of formula RX, in which: R denotes a hydrocarbon-based chain comprising from 2 to 50 carbon atoms, and the hydrocarbon-based chain is chosen from: a saturated or unsaturated linear alkyl chain, a saturated or unsaturated branched alkyl chain; and X denotes at least one ionizable group selected from the group consisting of: a carboxylic group, a sulfonate group, a sulfate group, a phosphonate group, a phosphate group, and a hydroxamate group.Type: ApplicationFiled: December 18, 2013Publication date: November 19, 2015Inventors: Lev Leon FILIPPOV, Inna KUVAEVA FILIPPOV, Jean-Marie Michel HOTTIER
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Patent number: 8457337Abstract: The invention provides systems and methods for providing hearing aid. An open ear canal hearing aid may be provided in accordance with an embodiment of the invention. The hearing aid may include a part that contains electronic components, a passive amplifier, and a securing mechanism. The securing mechanism may include bristles or balloons. The securing mechanism may have various configurations and be adjustable. In some embodiments, the hearing aid may transmit sound via bone conduction and air conduction.Type: GrantFiled: July 21, 2010Date of Patent: June 4, 2013Assignee: Aria Innovations, Inc.Inventors: Florent Nicolas Joseph Michel, Raphael Marie Michel, Daniel Zhiling Shen
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Publication number: 20110019851Abstract: The invention provides systems and methods for providing hearing aid. An open ear canal hearing aid may be provided in accordance with an embodiment of the invention. The hearing aid may include a part that contains electronic components, a passive amplifier, and a securing mechanism. The securing mechanism may include bristles or balloons. The securing mechanism may have various configurations and be adjustable. In some embodiments, the hearing aid may transmit sound via bone conduction and air conduction.Type: ApplicationFiled: July 21, 2010Publication date: January 27, 2011Inventors: Florent Nicolas Joseph MICHEL, Raphael Marie Michel, Daniel Zhiling Shen
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Recombinant HBsAg virus-like particles containing polyepitopes of interest, their production and use
Publication number: 20080171062Abstract: The hepatitis B surface antigen (HBsAg) can assemble into sub-virion virus like particles (VLPs). By fusing immunogenic peptides to the amino-terminus of HBsAg, several bivalent vaccines have been developed. In one example, an optimized HIV-1 polyepitope-HBsAg recombinant protein assembled into VLPs and was efficiently secreted. DNA immunization in mice resulted in the induction of humoral neutralising response against the carrier and enhanced levels of HIV-1 specific CD8+ T lymphocytes activation.Type: ApplicationFiled: August 9, 2007Publication date: July 17, 2008Inventors: Monica Sala-Schaeffer, Marie Michel, Simon Wain-Hobson -
Publication number: 20080166785Abstract: The hepatitis B surface antigen (HBsAg) can assemble into sub-virion virus like particles (VLPs). Vectors comprised of polynucleotides, identified as GA1xFlag-M and GA3xFlag-M, are provided for the expression of foreign proteins in such VLPs, and for release of the VLPs from host cells containing the vectors. In one example, an HIV-1 polyepitope-HBsAg recombinant fusion protein assembled into VLPs and was efficiently secreted.Type: ApplicationFiled: August 9, 2007Publication date: July 10, 2008Inventors: Monica Sala-Schaeffer, Marie Michel, Simon Wain-Hobson
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Patent number: 6884856Abstract: The present invention relates to a continuous process for controlling the gas-phase co-polymerisation of olefins in a fluidised bed reactor. The present invention further relates to a method for the continuous gas-phase (co-)polymerisation of olefins in a fluidised bed reactor in the presence of a polymerisation catalyst wherein the density of the polymer powder particles leaving the reactor is maintained constant by controlling the particle size distribution of the polymerisation catalyst. The present invention also relates to a process for controlling the particle size distribution of a polymerisation catalyst in order to achieve the production of a polymer powder of constant density during the continuous gas-phase (co-)polymerisation of olefins in a fluidised bed reactor.Type: GrantFiled: July 15, 2002Date of Patent: April 26, 2005Assignee: BP Chemicals LimitedInventors: Gacem Benazouzz, Claire Couronne, Sebastien Huchette, Patrick Leaney, Christel Maire-Claude Mealares, Frederic Robert Marie Michel Morterol, Renaud Viguier
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Publication number: 20040186249Abstract: The present invention relates to a continuous process for controlling the gas-phase co-polymerisation of olefins in a fluidised bed reactor. The present invention further relates to a method for the continuous gas-phase (co-)polymerisation of olefins in a fluidised bed reactor in the presence of a polymerisation catalyst wherein the density of the polymer powder particles leaving the reactor is maintained constant by controlling the particle size distribution of the polymerisation catalyst. The present invention also relates to a process for controlling the particle size distribution of a polymerisation catalyst in order to achieve the production of a polymer powder of constant density during the continuous gas-phase (co-)polymerisation of olefins in a fluidised bed reactor.Type: ApplicationFiled: January 15, 2004Publication date: September 23, 2004Inventors: Gacem Benazouzz, Claire Couronne, Sebastien Huchette, Patrick Leaney, Christel Maria-Claude Mealares, Frederic Robert Marie Michel Morterol, Renaud Viguier
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Patent number: 6656524Abstract: A continuous process for gas phase coating of polymerization catalyst. The polymerization catalyst is introduced in a gas phase plug flow type reactor wherein it is submitted to polymerization conditions in the presence of at least one monomer such that at least 95% by weight of the produced coated catalysts have a coating yield comprised between 0.5 to 2 times the average coating yield.Type: GrantFiled: February 1, 2001Date of Patent: December 2, 2003Assignee: BP Chemicals LimitedInventors: Daniel Claude Durand, Estelle Marie Joelle Meurice, Frederic Robert Marie Michel Morterol
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Patent number: D907998Type: GrantFiled: January 8, 2019Date of Patent: January 19, 2021Assignee: EYEon Innovations, LLCInventors: Anne Marie Michel, David William Reed