Patents by Inventor Marie-Noëlle Petit

Marie-Noëlle Petit has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRYSTALLINE PHASES OF 5,6-DICHLORO-2-(ISOPROPYLAMINO)-(1 BETA-L-RIBOFURANOSYL)-1H-BENZIMIDAZOLE
    Publication number: 20220372059
    Abstract: The invention relates to novel crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-(?-L-ribofuranosyl)-1H-benzimidazole (Maribavir), pharmaceutical compositions thereof and their use in medical therapy.
    Type: Application
    Filed: September 22, 2021
    Publication date: November 24, 2022
    Inventors: Gerard Coquerel, Guillaume Levilain, Marie-Noelle Petit, Servane Coste-Leconte
  • Crystalline phases of 5,6-dichloro-2-(isopropylamino)-(1-beta-L-ribofuranosyl)-1H-benzimidazole
    Patent number: 11130777
    Abstract: The invention relates to novel crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-(?-L-ribofuranosyl)-1H-benzimidazole (Maribavir), pharmaceutical compositions thereof and their use in medical therapy.
    Type: Grant
    Filed: March 22, 2019
    Date of Patent: September 28, 2021
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Gerard Coquerel, Guillaume Levilain, Marie-Noelle Petit, Servane Coste-Leconte
  • CRYSTALLINE PHASES OF 5,6-DICHLORO-2-(ISOPROPYLAMINO)-(1-BETA-L-RIBOFURANOSYL)-1H-BENZIMIDAZOLE
    Publication number: 20190352326
    Abstract: The invention relates to novel crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-(?-L-ribofuranosyl)-1H-benzimidazole (Maribavir), pharmaceutical compositions thereof and their use in medical therapy.
    Type: Application
    Filed: March 22, 2019
    Publication date: November 21, 2019
    Inventors: Gerard Coquerel, Guillaume Levilain, Marie-Noelle Petit, Servane Coste-Leconte
  • CRYSTALLINE PHASES OF 5,6-DICHLORO-2-(ISOPROPYLAMINO)-(1-BETA-L-RIBOFURANOSYL)-1H-BENZIMIDAZOLE
    Publication number: 20160304549
    Abstract: The invention relates to novel crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-(?-L-ribofuranosyl)-1H-benzimidazole (Maribavir), pharmaceutical compositions thereof and their use in medical therapy.
    Type: Application
    Filed: April 19, 2016
    Publication date: October 20, 2016
    Inventors: Gerard Coquerel, Guillaume Levilain, Marie-Noelle Petit, Servante Coste-Leconte
  • Method for the preparation of (3S,3S?) 4,4?-disulfanediylbis (3-aminobutane 1-sulfonic acid)
    Patent number: 9340497
    Abstract: The present invention relates to a new method for the preparation of (3S,3S?) 4,4?-disulfanediylbis(3-aminobutane 1-sulfonic acid) in five steps from (S)-ethyl 2-(benzyloxycarbonylamino)-4-(neopentyloxysulfonyl)butanoate A.
    Type: Grant
    Filed: October 27, 2015
    Date of Patent: May 17, 2016
    Assignee: QUANTUM GENOMICS
    Inventors: Fabrice Balavoine, Jonathan Madec, Jean-Marie Schneider, Gerard Coquerel, Nicolas Couvrat, Yohann Cartigny, Marie-Noelle Petit
  • METHOD FOR THE PREPARATION OF (3S,3S') 4,4'-DISULFANEDIYLBIS (3-AMINOBUTANE 1-SULFONIC ACID)
    Publication number: 20160046571
    Abstract: The present invention relates to a new method for the preparation of (3S,3S?) 4,4?-disulfanediylbis(3-aminobutane 1-sulfonic acid) in five steps from (S)-ethyl 2-(benzyloxycarbonylamino)-4-(neopentyloxysulfonyl)butanoate A.
    Type: Application
    Filed: October 27, 2015
    Publication date: February 18, 2016
    Inventors: Fabrice BALAVOINE, Jonathan MADEC, Jean-Marie SCHNEIDER, Gerard COQUEREL, Nicolas COUVRAT, Yohann CARTIGNY, Marie-Noelle PETIT
  • Method for the preparation of (3S, 3S?) 4,4?-disulfanediylbis (3-aminobutane 1-sulfonic acid)
    Patent number: 9187418
    Abstract: The present invention relates to a new method for the preparation of (3S,3S?) 4,4?-disulfanediylbis(3-aminobutane 1-sulfonic acid) in five steps from (S)-ethyl 2-(benzyloxycarbonylamino)-4-(neopentyloxysulfonyl)butanoate A.
    Type: Grant
    Filed: October 7, 2011
    Date of Patent: November 17, 2015
    Assignee: QUANTUM GENOMICS
    Inventors: Fabrice Balavoine, Jonathan Madec, Jean-Marie Schneider, Gérard Coquerel, Nicolas Couvrat, Yohann Cartigny, Marie-Noëlle Petit
  • SOLID PHARMACEUTICAL COMPOSITION CONTAINING 6-OXO-6,7,8,9,10,11-HEXAHYDROCYCLOHEPTA (C)CHROMEN-3-YL SULFAMATE AND POLYMORPHS THEREOF
    Publication number: 20140056977
    Abstract: The present invention relates to a solid pharmaceutical composition including the active principle 6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-3-yl sulfamate. The present invention also relates to polymorphs of the 6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-3-yl sulfamate compound.
    Type: Application
    Filed: August 1, 2013
    Publication date: February 27, 2014
    Applicant: Ipsen Pharma S.A.S.
    Inventors: Nathalie MONDOLY, Bertrand Poirot, Anne Brochard, Joël Richard, Delphine Delahaye, Christian Diolez, Alain Rolland, Francis Diancourt, Gérard Coquerel, Damien Martins, Julie Linol, Ophélie Houssin, Marie-Noêlle Petit, Barry, Victor, Lloyd Potter, Lok, Wai Lawrence Woo
  • Crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-?-L-ribofuranosyl)-1H-benzimidazole
    Patent number: 8546344
    Abstract: The invention relates to novel crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-(?-L-ribofuranosyl)-1H-benzimidazole (Maribavir), pharmaceutical compositions thereof and their use in medical therapy.
    Type: Grant
    Filed: October 27, 2011
    Date of Patent: October 1, 2013
    Assignee: ViroPharma Incorporated
    Inventors: Gerard Coquerel, Guillaume Levilain, Marie-Noelle Petit, Servane Coste-Leconte
  • Conglomerates of tenatoprazole potassium salts
    Patent number: 8546574
    Abstract: The invention relates to conglomerates of tenatoprazole potassium salts of the following general formula (I), that consist of an equimolar mixture of enantiomers having R and S configurations and capable of crystallization in the form of a conglomerate, wherein said salts are selected from tenatoprazole dehydrated potassium salt, tenatoprazole potassium dimethanolate, tenatoprazole potassium diethanolate and tenatoprazole potassium ethylene-glycolate. The invention also relates to a pharmaceutical composition containing such salt, and to the use of said salt.
    Type: Grant
    Filed: December 3, 2007
    Date of Patent: October 1, 2013
    Assignee: Sidem Pharma SA
    Inventors: Avraham Cohen, François Schutze, Suzy Charbit, Stéphane Bernad, Guillaume Tauvel, Marie-Noëlle Petit, Gérard Coquerel
  • METHOD FOR THE PREPARATION OF (3S, 3S') 4,4'-DISULFANEDIYLBIS (3-AMINOBUTANE 1-SULFONIC ACID)
    Publication number: 20130231500
    Abstract: The present invention relates to a new method for the preparation of (3S,3S?) 4,4?-disulfanediylbis(3-aminobutane 1-sulfonic acid) in five steps from (S)-ethyl 2-(benzyloxycarbonylamino)-4-(neopentyloxysulfonyl)butanoate A.
    Type: Application
    Filed: October 7, 2011
    Publication date: September 5, 2013
    Applicant: QUANTUM GEOMICS
    Inventors: Fabrice Balavoine, Jonathan Madec, Jean-Marie Schneider, Gérard Coquerel, Nicolas Couvrat, Yohann Cartigny, Marie-Noëlle Petit
  • SOLID PHARMACEUTICAL COMPOSITION CONTAINING 6-OXO-6,7,8,9,10,11-HEXAHYDROCYCLOHEPTA (C)CHROMEN-3-YL SULFAMATE AND POLYMORPHS THEREOF
    Publication number: 20120321714
    Abstract: The present invention relates to a solid pharmaceutical composition including the active principle 6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-3-yl sulfamate. The present invention also relates to polymorphs of the 6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-3-yl sulfamate compound.
    Type: Application
    Filed: March 26, 2012
    Publication date: December 20, 2012
    Applicant: Ipsen Pharma S.A.S.
    Inventors: Nathalie MONDOLY, Bertrand Poirot, Anne Brochard, Joël Richard, Delphine Delahaye, Christian Diolez, Alain Rolland, Francis Diancourt, Gérard Coquerel, Damien Martins, Julie Linol, Marie-Noêlle Petit, Barry Victor Llyod Potter, Lok, Wai Lawrence Woo
  • CRYSTALLINE PHASES OF 5,6-DFICHLORO-2-(ISOPROPYLAMINO)-1-ß-L-RIBOFURANOSYL)-1H-BENZIMIDAZOLE
    Publication number: 20120178709
    Abstract: The invention relates to novel crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-(?-L-ribofuranosyl)-1H-benzimidazole (Maribavir), pharmaceutical compositions thereof and their use in medical therapy.
    Type: Application
    Filed: October 27, 2011
    Publication date: July 12, 2012
    Inventors: Gerard Coquerel, Guillaume Levilain, Marie-Noelle Petit, Servane Coste-Leconte
  • Method for resolving omeprazole salts
    Patent number: 8034948
    Abstract: The present invention relates to the resolution by preferential crystallization of potassium salts of racemic omeprazole which is a solvate of ethanol and/or of ethylene glycol, which consists in converting the omeprazole to the potassium salt in the form of a solvate or of a mixture of these solvates in the presence of an excess of inorganic base which is a source of potassium, the said potassium salts existing in the form of conglomerates, and in then resolving the said conglomerates, independently or simultaneously, by preferential crystallization in order to separate the two (S) and (R) enantiomers of these potassium salts of omeprazole.
    Type: Grant
    Filed: August 29, 2008
    Date of Patent: October 11, 2011
    Assignee: Universite de Rouen
    Inventors: Gérard Coquerel, Guillaume Tauvel, Marie-Noelle Petit
  • CONGLOMERATES OF TENATOPRAZOLE POTASSIUM SALTS
    Publication number: 20110060002
    Abstract: The invention relates to conglomerates of tenatoprazole potassium salts of the following general formula (I), that consist of an equimolar mixture of enantiomers having R and S configurations and capable of crystallisation in the form of a conglomerate, wherein said salts are selected from tenatoprazole dehydrated potassium salt, tenatoprazole potassium dimethanolate, tenatoprazole potassium diethanolate and tenatoprazole potassium ethylene-glycolate. The invention also relates to a pharmaceutical composition containing such salt, and to the use of said salt.
    Type: Application
    Filed: December 3, 2007
    Publication date: March 10, 2011
    Applicant: SIDEM PHARAMA SA
    Inventors: Avraham Cohen, Francois Schutze, Suzy Charbit, Stéphane Bernad, Cuillaume Tauvel, Marie-Noëlle Petit, Gérard Coquerel
  • Method for resolving omeprazole salts
    Publication number: 20090124811
    Abstract: The present invention relates to the resolution by preferential crystallization of potassium salts of racemic omeprazole which is a solvate of ethanol and/or of ethylene glycol, which consists in converting the omeprazole to the potassium salt in the form of a solvate or of a mixture of these solvates in the presence of an excess of inorganic base which is a source of potassium, the said potassium salts existing in the form of conglomerates, and in then resolving the said conglomerates, independently or simultaneously, by preferential crystallization in order to separate the two (S) and (R) enantiomers of these potassium salts of omeprazole.
    Type: Application
    Filed: August 29, 2008
    Publication date: May 14, 2009
    Applicant: UNIVERSITE DE ROUEN
    Inventors: Gerard COQUEREL, Guillaume TAUVEL, Marie-Noelle PETIT
  • Polymorphic forms of fasidotril, their methods of preparation and pharmaceutical compositions comprising them
    Patent number: 6767921
    Abstract: The subject of the present invention is the various polymorphic forms I, II, III, IV of benzyl (S,S)-2-(2-acetylsulphanylmethyl-3-benzo[1,3]dioxol-5-ylpropionyl-amino)propionate, hereinafter called Fasidotril, their methods of preparation and novel pharmaceutical compositions containing them.
    Type: Grant
    Filed: March 26, 2003
    Date of Patent: July 27, 2004
    Assignee: Bioproject
    Inventors: Marc Capet, Gérard Coquerel, Denis Danvy, Jeanne-Marie Lecomte, Marie-Noëlle Petit, Jean-Charles Schwartz
  • Polymorphic forms of fasidotril, their methods of preparation and pharmaceutical compositions comprising them
    Publication number: 20030203965
    Abstract: The subject of the present invention is the various polymorphic forms I, II, III, IV of benzyl (S,S)-2-(2-acetylsulphanylmethyl-3-benzo[1,3]dioxol-5-ylpropionyl-amino)propionate, hereinafter called Fasidotril, their methods of preparation and novel pharmaceutical compositions containing them.
    Type: Application
    Filed: March 26, 2003
    Publication date: October 30, 2003
    Inventors: Marc Capet, Gerard Coquerel, Denis Danvy, Jeanne-Marie Lecomte, Marie-Noelle Petit, Jean-Charles Schwartz
  • Method of resolution of two enantiomers by crystallization
    Patent number: 6022409
    Abstract: A method of optical enantiomer resolution by preferential crystallization involves entering, each time crystallization starts, the two-phase domain containing excess enantiomer and the saturated solution, and cooling according to a well-defined kinetic schedule. A racemic mixture of fine particle size is added to the mother liquors obtained after harvesting the crystals, the mother liquors then being heated to a temperature lower than that of homogenization of the solution so that excess enantiomer is present only in a solid state in equilibrium with the solution. Further cooling produces the other enantiomer and completes the cycle of operations which may then be carried out repetitively.
    Type: Grant
    Filed: October 2, 1996
    Date of Patent: February 8, 2000
    Assignee: The University of Rouen
    Inventors: Gerard Coquerel, Marie-Noelle Petit, Roger Bouaziz