Patents by Inventor Marie-Odile Galcera Contour

Marie-Odile Galcera Contour has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of cdc phosphatases
    Patent number: 8017637
    Abstract: A subject of the present invention is novel compounds comprising 2 or 3 benzothiazole-4,7-dione- or benzooxazole-4,7-dione-type units, which inhibit the cdc25 phosphatases, in particular cdc25-C phosphatase. These compounds can in particular be used in the treatment of cancer.
    Type: Grant
    Filed: December 16, 2005
    Date of Patent: September 13, 2011
    Assignee: Ipsen Pharma S.A.S.
    Inventors: Marie-Odile Galcera-Contour, Dennis Bigg, Grégoire Prevost, Alban Sidhu
  • 4,7-Dioxobenzothiazole-2-Carboxamide Derivatives, Their Preparation And Their Therapeutic Uses
    Publication number: 20100317658
    Abstract: A subject of the present invention is 4,7-dioxobenzothiazole-2-carboxamide derivatives, which inhibit the cdc25 phosphatases, in particular cdc25-C phosphatase. These compounds can in particular be used in the treatment of cancer.
    Type: Application
    Filed: August 3, 2010
    Publication date: December 16, 2010
    Applicant: Ipsen Pharma S.A.S.
    Inventors: Marie-Odile Galcera-Contour, Grégoire Prevost, Alban Sidhu
  • 4,7-dioxobenzothiazole-2-carboxamide derivatives, their preparation and their therapeutic uses
    Patent number: 7795284
    Abstract: A subject of the present invention is 4,7-dioxobenzothiazole-2-carboxamide derivatives, which inhibit the cdc25 phosphatases, in particular cdc25-C phosphatase. These compounds can in particular be used in the treatment of cancer.
    Type: Grant
    Filed: November 7, 2005
    Date of Patent: September 14, 2010
    Assignee: Ipsen Pharma S.A.S.
    Inventors: Marie-Odile Galcera-Contour, Grégoire Prevost, Alban Sidhu
  • INHIBITORS OF CDC PHOSPHATASES
    Publication number: 20090275624
    Abstract: A subject of the present invention is novel compounds comprising 2 or 3 benzothiazole-4,7-dione- or benzooxazole-4,7-dione-type units, which inhibit the cdc25 phosphatases, in particular cdc25-C phosphatase. These compounds can in particular be used in the treatment of cancer.
    Type: Application
    Filed: December 16, 2005
    Publication date: November 5, 2009
    Applicant: Societe de Conseils de Recherches et D'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Marie-Odile Galcera-Contour, Dennis Bigg, Grégoire Prevost, Alban Sidhu
  • BENZOOXAZOLE-4,7-DIONE, DERIVATIVES AND THEIR USE AS CDC25 PHOSPHATE INHIBITORS
    Publication number: 20090131428
    Abstract: The invention concerns the use as cdc25 phosphatase inhibitors, in particular cdc25-C phosphatase, and CD45 phosphatase, of compounds of general formula (I), wherein: W represents O or S. In accordance with the invention, the compounds of general formula (I) can in particular be used for preparing a medicine for cancer treatment.
    Type: Application
    Filed: October 6, 2008
    Publication date: May 21, 2009
    Applicant: Societe de Conseils de Recherches et D'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Marie-Odile Galcera Contour, Olivier Lavergne, Marie-Christine Brezak Pannetier, Gregoire Prevost
  • BENZOTHIAZOLE- AND BENZOOXAZOLE-4,7-DIONE, DERIVATIVES AND THEIR USE AS CDC25 PHOSPHATE INHIBITORS
    Publication number: 20090082345
    Abstract: The invention concerns the use as cdc25 phosphatase inhibitors, in particular cdc25-C phosphatase, and CD45 phosphatase, of compounds of general formula (I), wherein: W represents O or S. In accordance with the invention, the compounds of general formula (I) can in particular be used for preparing a medicine for cancer treatment.
    Type: Application
    Filed: October 3, 2008
    Publication date: March 26, 2009
    Applicant: Societe de Conseils de Recherches et D'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Marie-Odile GALCERA CONTOUR, Olivier Lavergne, Marie-Christine Brezak Pannetier, Gregoire Prevost
  • Benzothiazole- and benzooxazole-4,7-dione, derivatives and their use as cdc25 phosphate inhibitors
    Patent number: 7495021
    Abstract: The invention concerns the use as cdc25 phosphatase inhibitors, in particular cdc25-C phosphatase, and CD45 phosphatase, of compounds of general formula (I), wherein: W represents O or S. In accordance with the invention, the compounds of general formula (I) can in particular be used for preparing a medicine for cancer treatment.
    Type: Grant
    Filed: August 31, 2007
    Date of Patent: February 24, 2009
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Marie-Odile Galcera Contour, Olivier Lavergne, Marie-Christine Brezak Pannetier, Grégoire Prevost
  • Benzothiazole-4,7-diones and benzoxazole-4,7-diones with substituents in position 5 or 6 and method for production thereof
    Patent number: 7335674
    Abstract: A targetted production method for benzothiazole-4,7-dione and benzoxazole-4,7-dione derivatives, mono-substituted in the 5 or 6 position with an amino group, itself optionally substituted.
    Type: Grant
    Filed: June 24, 2004
    Date of Patent: February 26, 2008
    Assignee: Societe de Conseils de Recherches et d'Applications (S.C.R.A.S.)
    Inventors: Marie-Odile Galcera Contour, Olivier Lavergne
  • BENZOTHIAZOLE- AND BENZOOXAZOLE-4,7-DIONE, DERIVATIVES AND THEIR USE AS CDC25 PHOSPHATE INHIBITORS
    Publication number: 20070293487
    Abstract: The invention concerns the use as cdc25 phosphatase inhibitors, in particular cdc25-C phosphatase, and CD45 phosphatase, of compounds of general formula (I), wherein: W represents O or S. In accordance with the invention, the compounds of general formula (I) can in particular be used for preparing a medicine for cancer treatment.
    Type: Application
    Filed: August 31, 2007
    Publication date: December 20, 2007
    Applicant: Societ de Conseils de Recherches et D'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Marie-Odile GALCERA CONTOUR, Olivier Levergne, Marie-Christine Brezak Pannetier, Gregoire Prevost
  • BENZOTHIAZOLE- AND BENZOOXAZOLE-4,7-DIONE, DERIVATIVES AND THEIR USE AS CDC25 PHOSPHATE INHIBITORS
    Publication number: 20070255063
    Abstract: Heterocyclic dione compounds as disclosed in the specification, compositions thereof and methods for the use thereof, for the treatment of T cell-mediated conditions such as autoimmune diseases and organ graft rejection.
    Type: Application
    Filed: May 22, 2007
    Publication date: November 1, 2007
    Applicant: Societe de Conseils de Recherches et D'Application Scientifiques (S.C.R.A.S.)
    Inventors: Marie-Odile Galcera Contour, Olivier Lavergne, Marie-Christine Brezak Pannetier, Gregoire Prevost
  • 4, 7-Dioxobenzothiazole-2-Carboxamide Derivatives, Their Preparation and Their Therapeutic Uses
    Publication number: 20070244186
    Abstract: A subject of the present invention is 4,7-dioxobenzothiazole-2-carboxamide derivatives, which inhibit the cdc25 phosphatases, in particular cdc25-C phosphatase. These compounds can in particular be used in the treatment of cancer.
    Type: Application
    Filed: November 7, 2005
    Publication date: October 18, 2007
    Inventors: Marie-Odile Galcera-Contour, Gregoire Prevost, Alban Sidhu
  • Benzothiazole-and benzoxazole-4, 7-dione derivatives and their use as dcd25 phosphatase inhibitors
    Patent number: 7279467
    Abstract: The invention concerns the use as cdc25 phosphatase inhibitors, in particular cdc25-C phosphatase, and CD45 phosphatase, of compounds of general formula (I), wherein: W represents O or S.
    Type: Grant
    Filed: December 24, 2002
    Date of Patent: October 9, 2007
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Marie-Odile Galcera Contour, Olivier Lavergne, Marie-Christine Brezak Pannetier, Grégoire Prevost
  • Cdc25 phosphatase inhibitors
    Patent number: 7196084
    Abstract: The invention concerns novel cdc25 phosphatase inhibitors, and in particular cdc25-C, which correspond to the general formula (I) wherein: A represents a carbocyclic aryl radical optionally substituted 1 to 3 times by one or more radicals independently selected among a halogen atom and an alkyl, hydroxy, alkoxy, alkylthio or NR1R2 radical wherein R1 and R2 represent a hydrogen atom or an alkyl radical or R1 and R2 form together with the nitrogen atom a heterocycle of 4 to 7 members comprising 1 to 2 heteroatoms, the members required to complete the heterocycle being selected independently among the CR3R4—, —O—, —S and NR5-radicals, R3 and R4 representing independently each time they are involved a hydrogen atom or an alkyl, hydroxy, alkoxy, amino, alkylamino or dialkylamino radical, and R5 representing independently each time it is involved a hydrogen atom or an alkyl radical, or A represents a phenyl radical substituted by a phenyl radical optionally substituted 1 to 3 times by one or more radicals selected
    Type: Grant
    Filed: July 26, 2001
    Date of Patent: March 27, 2007
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Grégoire Prevost, Marie-Christine Brezak Pannetier, Marie-Odile Galcera Contour, Christophe Thurieau, Françoise Goubin Gramatica, Bernard Ducommun, Christophe Lanco
  • Inhibitors of cdc25 phosphatases
    Publication number: 20060235027
    Abstract: A method of inhibiting cdc25 phosphatases in warm-blooded animals comprising administering to warm-blooded animals in need thereof an effective amount of a compound of the formula wherein the substituents are defined as in the specification.
    Type: Application
    Filed: April 25, 2006
    Publication date: October 19, 2006
    Inventors: Gregoire Prevost, Marie-Christine Brezak Pannetier, Marie-Odile Galcera Contour, Christophe Thurieau, Francoise Goubin Gramatica, Bernard Ducommun, Christophe Lanco
  • Inhibitors of Cdc25 phosphatases
    Publication number: 20060154933
    Abstract: A method of inhibiting cdc25 phosphatases in warm-blooded animals comprising administering to warm-blooded animals in need thereof an effective amount of a compound of the formula wherein the substituents are defined as in the specification.
    Type: Application
    Filed: February 9, 2006
    Publication date: July 13, 2006
    Inventors: Gregoire Prevost, Marie-Christine Brezak Pannetier, Marie-Odile Galcera Contour, Christophe Thurieau, Francoise Gramatica, Bernard Ducommun, Christophe Lanco
  • Benzothiazole-4,7-diones and benzoxazole-4,7-diones with substituents in position 5 or 6 and method for production thereof
    Publication number: 20060135573
    Abstract: A subject of the invention is a selective process for the preparation of derivatives of benzothiazole-4,7-diones and benzoxazole-4,7-diones monosubstituted in position 5 or in position 6 by an amino group itself optionally substituted. Said derivatives are inhibitors of the Cdc25 phosphatases and can be used for preparing medicaments intended to treat cancer. The invention also offers synthesis intermediates which are useful in implementing the process of the invention. The invention also relates in particular to the following derivatives of benzothiazole-4,7-diones: 2-(2-chloro-6-fluorophenyl)-5-{[2-(dimethylamino)ethyl]amino}-1,3-benzothiazole-4,7-dione; 2-(2-chloro-6-fluorophenyl)-5-[(2-pyrrolidin-1-ylethyl)amino]-1,3-benzothiazole-4,7-dione.
    Type: Application
    Filed: June 24, 2004
    Publication date: June 22, 2006
    Inventors: Marie-Odile Galcera Contour, Olivier Lavergne
  • Benzothiazole-and benzoxazole-4, 7-dione derivatives and their use as dcd25 phosphatase inhibitors
    Publication number: 20060040996
    Abstract: The invention concerns the use as cdc25 phosphatase inhibitors, in particular cdc25-C phosphatase, and CD45 phosphatase, of compounds of general formula (I), wherein: W represents O or S. In accordance with the invention, the compounds of general formula (I) can in particular be used for preparing a medicine for cancer treatment.
    Type: Application
    Filed: December 24, 2002
    Publication date: February 23, 2006
    Inventors: Marie-Odile Galcera Contour, Olivier Lavergne, Marrie-Christine Brezak Pannetier, Gregoire Prevost
  • Cdc25 photophatase inhibitors
    Publication number: 20040034103
    Abstract: The invention concerns novel cdc25 phosphatase inhibitors, and in particular cdc25-C, which correspond to the general formula (I) wherein: A represents a carbocyclic aryl radical optionally substituted 1 to 3 times by one or more radicals independently selected among a halogen atom and an alkyl, hydroxy, alkoxy, alkylthio or NR1R2 radical wherein R1 and R2 represent a hydrogen atom or an alkyl radical or R1 and R2 form together with the nitrogen atom a heterocycle of 4 to 7 members comprising 1 to 2 heteroatoms, the members required to complete the heterocycle being selected independently among the CR3R4—, —O—, —S and NR5-radicals, R3 and R4 representing independently each time they are involved a hydrogen atom or an alkyl, hydroxy, alkoxy, amino, alkylamino or dialkylamino radical, and R5 representing independently each time it is involved a hydrogen atom or an alkyl radical, or A represents a phenyl radical substituted by a phenyl radical optionally substituted 1 to 3 times by one or
    Type: Application
    Filed: January 27, 2003
    Publication date: February 19, 2004
    Inventors: Gregoire Prevost, Marie-Christine Brezak Pannetier, Marie-Odile Galcera Contour, Christophe Thurieau, Francoise Goubin Gramatica, Bernard Ducommun, Christophe Lanco