Patents by Inventor Marie-Pierre Piccinni

Marie-Pierre Piccinni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190094234
    Abstract: A method of obtaining a class of embryos having a higher implantation potential than from morphology selection alone by selecting from multiple embryos, obtained by fertilizing the plurality of oocytes, a class of embryos having a high implantation potential. The selection is determined from a level of granulocyte-colony stimulating factor (G-CSF) present in the follicular fluid (FF) of each oocyte in the multiple oocytes.
    Type: Application
    Filed: November 27, 2018
    Publication date: March 28, 2019
    Inventors: Nathalie Ledee, Marie-Pierre Piccinni
  • Patent number: 10180438
    Abstract: A method is described to obtain a class of embryos having a higher implantation potential than from morphology selection alone by selecting from a plurality of embryos, obtained by fertilizing the plurality of oocytes, a class of embryos having a high implantation potential. The selection is determined from a level of granulocyte-colony stimulating factor (G-CSF) present in the follicular fluid (FF) of each oocyte in the plurality of oocytes.
    Type: Grant
    Filed: May 17, 2017
    Date of Patent: January 15, 2019
    Assignee: FEMALON S.P.R.L.
    Inventors: Nathalie Ledee, Marie-Pierre Piccinni
  • Publication number: 20180088125
    Abstract: A method is described to obtain a class of embryos having a higher implantation potential than from morphology selection alone by selecting from a plurality of embryos, obtained by fertilizing the plurality of oocytes, a class of embryos having a high implantation potential. The selection is determined from a level of granulocyte-colony stimulating factor (G-CSF) present in the follicular fluid (FF) of each oocyte in the plurality of oocytes.
    Type: Application
    Filed: May 17, 2017
    Publication date: March 29, 2018
    Inventors: Nathalie Ledee, Marie-Pierre Piccinni
  • Patent number: 9664692
    Abstract: A kit for determining for a female subject the implantation potential of embryos obtained or to be obtained by assisted fertilization is described. The kit includes at least one reagent suitable for detection of levels of FF G-CSF or FF G-CSF mRNA, such as anti-G-CSF antibody or a nucleic acid probe for detection of levels of G-CSF mRNA. The kit may also include a set of concentration standards of FF G-CSF and aspirator tips for removing an oocyte and follicular fluid.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: May 30, 2017
    Assignee: FEMALON S.P.R.L.
    Inventors: Nathalie Ledee, Marie-Pierre Piccinni
  • Publication number: 20160047818
    Abstract: A kit for determining for a female subject the implantation potential of embryos obtained or to be obtained by assisted fertilization is described. The kit includes at least one reagent suitable for detection of levels of FF G-CSF or FF G-CSF mRNA, such as anti-G-CSF antibody or a nucleic acid probe for detection of levels of G-CSF mRNA. The kit may also include a set of concentration standards of FF G-CSF and aspirator tips for removing an oocyte and follicular fluid.
    Type: Application
    Filed: October 29, 2015
    Publication date: February 18, 2016
    Inventors: Nathalie Ledee, Marie-Pierre Piccinni
  • Patent number: 9176145
    Abstract: A kit for determining for a female subject the implantation potential of embryos obtained or to be obtained by assisted fertilization is described. The kit includes at least one reagent suitable for detection of levels of FF G-CSF or FF G-CSF mRNA, such as anti-G-CSF antibody or a nucleic acid probe for detection of levels of G-CSF mRNA. The kit may also include a set of concentration standards of FF G-CSF and aspirator tips for removing an oocyte and follicular fluid.
    Type: Grant
    Filed: July 2, 2012
    Date of Patent: November 3, 2015
    Assignee: FEMALON S.P.R.L.
    Inventors: Nathalie Lédée, Marie-Pierre Piccinni
  • Publication number: 20120283673
    Abstract: A kit for determining for a female subject the implantation potential of embryos obtained or to be obtained by assisted fertilization is described. The kit includes at least one reagent suitable for detection of levels of FF G-CSF or FF G-CSF mRNA, such as anti-G-CSF antibody or a nucleic acid probe for detection of levels of G-CSF mRNA. The kit may also include a set of concentration standards of FF G-CSF and aspirator tips for removing an oocyte and follicular fluid.
    Type: Application
    Filed: July 2, 2012
    Publication date: November 8, 2012
    Applicant: Femalon S.A.
    Inventors: Nathalie Lédée, Marie-Pierre Piccinni
  • Patent number: 8211650
    Abstract: The present invention relates to an assay for determining the implantation potential of a plurality of embryos each obtained or to be obtained by assisted fertilization of an oocyte of a female subject, comprising measuring the levels of granulocyte-colony stimulating factor (G-CSF) in the follicular fluid (FF) present in the follicle from which each oocyte is derived, and determining the implantation potential of each embryo from the level of measured FF G-CSF. It also relates to a kit for carrying out the assay. It further relates to a method for assisted fertilization.
    Type: Grant
    Filed: July 18, 2007
    Date of Patent: July 3, 2012
    Assignee: Femalon S.A.
    Inventors: Nathalie Ledee, Marie-Pierre Piccinni, Raoul Lombroso
  • Publication number: 20090312596
    Abstract: The present invention relates to an assay for determining the implantation potential of a plurality of embryos each obtained or to be obtained by assisted fertilisation of an oocyte of a female subject, comprising measuring the levels of granulocyte-colony stimulating factor (G-CSF) in the follicular fluid (FF) present in the follicle from which each oocyte is derived, and determining the implantation potential of each embryo from the level of measured FF G-CSF. It also relates to a kit for carrying out the assay. It further relates to a method for assisted fertilisation.
    Type: Application
    Filed: July 18, 2007
    Publication date: December 17, 2009
    Applicant: Mithra Pharmaceuticals NV/SA
    Inventors: Nathalie Lédée, Marie-Pierre Piccinni, Raoul Lombroso