Patents by Inventor Marie Rosier

Marie Rosier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nuclear factor ?B inducing factor
    Patent number: 8642739
    Abstract: The present invention is directed to nuclear factor ?B (NF?B)-inducing factor polypeptides (NFIF polypeptides) which are capable of inducing NF?B. The present invention includes within its scope NFIF polypeptides, including NFIF-14b and NFIF-7a, DNA, including cDNA, encoding these polypeptides, and expression vectors capable of expressing NFIF polypeptides. Also included are methods and compositions for increasing NF?B induction in a patient, methods and compositions for lowering NF?B induction in a patient, methods for inhibiting inflammation, and methods for manufacture of a medicament intended for the treatment and/or prevention of an NF?B-regulated inflammatory response. In addition, methods for determining whether a test compound inhibits or enhances the activity of NFIF polypeptides are provided.
    Type: Grant
    Filed: June 10, 2011
    Date of Patent: February 4, 2014
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Patrice Denefle, Thomas F. Haws, June M. Kaplow, Marie Rosier
  • Nuclear factor ?B inducing factor
    Patent number: 8623831
    Abstract: The present invention is directed to nuclear factor ?B (NF?B)-inducing factor polypeptides (NFIF polypeptides) which are capable of inducing NF?B. The present invention includes within its scope NFIF polypeptides, including NFIF-14b and NFIF-7a, DNA, including cDNA, encoding these polypeptides, and expression vectors capable of expressing NFIF polypeptides. Also included are methods and compositions for increasing NF?B induction in a patient, methods and compositions for lowering NF?B induction in a patient, methods for inhibiting inflammation, and methods for manufacture of a medicament intended for the treatment and/or prevention of an NF?B-regulated inflammatory response. In addition, methods for determining whether a test compound inhibits or enhances the activity of NFIF polypeptides are provided.
    Type: Grant
    Filed: June 10, 2011
    Date of Patent: January 7, 2014
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: Patrice Denefle, Thomas F. Haws, June M. Kaplow, Marie Rosier
  • NUCLEAR FACTOR kappaB INDUCING FACTOR
    Publication number: 20110263831
    Abstract: The present invention is directed to nuclear factor ?B (NF?B)-inducing factor polypeptides (NFIF polypeptides) which are capable of inducing NF?B. The present invention includes within its scope NFIF polypeptides, including NFIF-14b and NFIF-7a, DNA, including cDNA, encoding these polypeptides, and expression vectors capable of expressing NFIF polypeptides. Also included are methods and compositions for increasing NF?B induction in a patient, methods and compositions for lowering NF?B induction in a patient, methods for inhibiting inflammation, and methods for manufacture of a medicament intended for the treatment and/or prevention of an NF?B-regulated inflammatory response. In addition, methods for determining whether a test compound inhibits or enhances the activity of NFIF polypeptides are provided.
    Type: Application
    Filed: June 10, 2011
    Publication date: October 27, 2011
    Applicant: AVENTIS PHARMACEUTICALS INC.
    Inventors: June KAPLOW, Thomas HAWS, Marie ROSIER, Patrice DENEFLE
  • NUCLEAR FACTOR kappaB INDUCING FACTOR
    Publication number: 20110245471
    Abstract: The present invention is directed to nuclear factor ?B (NF?B)-inducing factor polypeptides (NFIF polypeptides) which are capable of inducing NF?B. The present invention includes within its scope NFIF polypeptides, including NFIF-14b and NFIF-7a, DNA, including cDNA, encoding these polypeptides, and expression vectors capable of expressing NFIF polypeptides. Also included are methods and compositions for increasing NF?B induction in a patient, methods and compositions for lowering NF?B induction in a patient, methods for inhibiting inflammation, and methods for manufacutre of a medicament intended for the treatment and/or prevention of an NF?B-regulated inflammatory response. In addition, methods for determining whether a test compound inhibits or enhances the activity of NFIF polypeptides are provided.
    Type: Application
    Filed: June 10, 2011
    Publication date: October 6, 2011
    Applicant: AVENTIS PHARMACEUTICALS INC.
    Inventors: June KAPLOW, Thomas HAWS, Marie ROSIER, Patrice DENEFLE
  • Nuclear factor ?B inducing factor
    Patent number: 7972844
    Abstract: The present invention is directed to nuclear factor ?B (NF?B)-inducing factor polypeptides (NFIF polypeptides) which are capable of inducing NF?B. The present invention includes within its scope NFIF polypeptides, including NFIF-14b and NFIF-7a, DNA, including cDNA, encoding these polypeptides, and expression vectors capable of expressing NFIF polypeptides. Also included are methods and compositions for increasing NF?B induction in a patient, methods and compositions for lowering NF?B induction in a patient, methods for inhibiting inflammation, and methods for manufacture of a medicament intended for the treatment and/or prevention of an NF?B-regulated inflammatory response. In addition, methods for determining whether a test compound inhibits or enhances the activity of NFIF polypeptides are provided.
    Type: Grant
    Filed: February 15, 2006
    Date of Patent: July 5, 2011
    Assignee: Aventis Pharmaceuticals Inc.
    Inventors: June Kaplow, Thomas Haws, Marie Rosier, Patrice Denefle
  • Nuclear factor kappaB inducing factor
    Publication number: 20060223771
    Abstract: The present invention is directed to nuclear factor ?B (NF?B)-inducing factor polypeptides (NFIF polypeptides) which are capable of inducing NF?B. The present invention includes within its scope NFIF polypeptides, including NFIF-14b and NFIF-7a, DNA, including cDNA, encoding these polypeptides, and expression vectors capable of expressing NFIF polypeptides. Also included are methods and compositions for increasing NF?B induction in a patient, methods and compositions for lowering NF?B induction in a patient, methods for inhibiting inflammation, and methods for manufacutre of a medicament intended for the treatment and/or prevention of an NF?B-regulated inflammatory response. In addition, methods for determining whether a test compound inhibits or enhances the activity of NFIF polypeptides are provided.
    Type: Application
    Filed: February 15, 2006
    Publication date: October 5, 2006
    Applicant: Aventis Pharmaceuticals Products Inc.
    Inventors: June Kaplow, Thomas Haws, Marie Rosier, Patrice Denefle
  • Nuclear factor ?B inducing factor
    Patent number: 7041497
    Abstract: The present invention is directed to nuclear factor ?B (NF?B)-inducing factor polypeptides (NFIF polypeptides) which are capable of inducing NF?B. The present invention includes within its scope NFIF polypeptides, including NFIF-14b and NFIF-7a, DNA, including cDNA, encoding these polypeptides, and expression vectors capable of expressing NFIF polypeptides. Also included are methods and compositions for increasing NF?B induction in a patient, methods and compositions for lowering NF?B induction in a patient, methods for inhibiting inflammation, and methods for manufacture of a medicament intended for the treatment and/or prevention of an NF?B-regulated inflammatory response. In addition, methods for determining whether a test compound inhibits or enhances the activity of NFIF polypeptides are provided.
    Type: Grant
    Filed: March 30, 2001
    Date of Patent: May 9, 2006
    Assignee: Aventis Pharmaceuticals Products Inc.
    Inventors: June Kaplow, Thomas Haws, Marie Rosier, Patrice Denefle
  • Nucleic acids of the human ABCC12 gene, vectors containing such nucleic acids and uses thereof
    Publication number: 20060063166
    Abstract: The present invention relates to a novel human ABCC12 gene as well as the cDNAs encoding the novel short and long of ABCC12 proteins isoforms. The invention also relates to vectors and recombinant host cells comprising such nucleic acids, nucleotide probes and primers, and means for the detection of polymorphisms and mutations in the ABCC12 gene or in the corresponding proteins isoforms produced by the allelic form of the ABCC12 gene.
    Type: Application
    Filed: December 16, 2004
    Publication date: March 23, 2006
    Applicant: Aventis Pharma S. A.
    Inventors: Marie Rosier, Catherine Prades, Isabelle Arnould, Michael Dean, Rando Allikmets, Patrice Denefle
  • Nucleic acids of the human ABCC11 gene, vectors containing such nucleic acids and uses thereof
    Publication number: 20050158784
    Abstract: The present invention relates to nucleic acids corresponding to various exons of the ABCC11 gene as well as the cDNA encoding the novel full length of ABCC11 protein. The invention also relates to means for the detection of polymorphisms in general, and of mutations in particular, in the ABCC11 gene or in the corresponding protein produced by the allelic form of the ABCC11 gene.
    Type: Application
    Filed: January 12, 2005
    Publication date: July 21, 2005
    Applicant: Aventis Pharma S.A.
    Inventors: Marie Rosier, Catherine Prades, Isabelle Arnould, Michael Dean, Rando Allikmets, Patrice Denefle
  • Nucleic acids of the human ABCC11 gene, vectors containing such nucleic acids and uses thereof
    Patent number: 6893841
    Abstract: The present invention relates to nucleic acids corresponding to various exons of the ABCC11 gene as well as the cDNA encoding the novel full length of ABCC11 protein. The invention also relates to means for the detection of polymorphisms in general, and of mutations in particular, in the ABCC11 gene or in the corresponding protein produced by the allelic form of the ABCC11 gene.
    Type: Grant
    Filed: March 5, 2002
    Date of Patent: May 17, 2005
    Assignee: Aventis Pharma S.A.
    Inventors: Marie Rosier, Catherine Prades, Isabelle Arnould, Michael Dean, Rando Allikmets, Patrice Denefle
  • Nuclear factor kappaB inducing factor
    Publication number: 20030170862
    Abstract: The present invention is directed to nuclear factor &kgr;B (NF&kgr;B)-inducing factor polypeptides (NFIF polypeptides) which are capable of inducing NF&kgr;B. The present invention includes within its scope NFIF polypeptides, including NFIF-14b and NFIF-7a, DNA, including cDNA, encoding these polypeptides, and expression vectors capable of expressing NFIF polypeptides. Also included are methods and compositions for increasing NF&kgr;B induction in a patient, methods and compositions for lowering NF&kgr;B induction in a patient, methods for inhibiting inflammation, and methods for manufacutre of a medicament intended for the treatment and/or prevention of an NF&kgr;B-regulated inflammatory response. In addition, methods for determining whether a test compound inhibits or enhances the activity of NFIF polypeptides are provided.
    Type: Application
    Filed: March 30, 2001
    Publication date: September 11, 2003
    Inventors: June Kaplow, Thomas Haws, Marie Rosier, Patrice Denefle
  • Nucleic acids of the human ABCC12 gene, vectors containing such nucleic acids, and uses thereof
    Publication number: 20030077605
    Abstract: The present invention relates to a novel human ABCC12 gene as well as the cDNAs encoding the novel short and long of ABCC12 proteins isoforms. The invention also relates to vectors and recombinant host cells comprising such nucleic acids, nucleotide probes and primers, and means for the detection of polymorphisms and mutations in the ABCC12 gene or in the corresponding proteins isoforms produced by the allelic form of the ABCC12 gene.
    Type: Application
    Filed: March 5, 2002
    Publication date: April 24, 2003
    Inventors: Marie Rosier, Catherine Prades, Isabelle Arnould, Michael Dean, Rando Allikmets, Patrice Denefle
  • Nucleic acids of the human ABCC11 gene, vectors containing such nucleic acids and uses thereof
    Publication number: 20030059793
    Abstract: The present invention relates to nucleic acids corresponding to various exons of the ABCC11 gene as well as the cDNA encoding the novel full length of ABCC11 protein. The invention also relates to means for the detection of polymorphisms in general, and of mutations in particular, in the ABCC11 gene or in the corresponding protein produced by the allelic form of the ABCC11 gene.
    Type: Application
    Filed: March 5, 2002
    Publication date: March 27, 2003
    Inventors: Marie Rosier, Catherine Prades, Isabelle Arnould, Michael Dean, Rando Allikmets, Patrice Denefle