Patents by Inventor Marielena Gamboa

Marielena Gamboa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240382606
    Abstract: The present disclosure relates to nanoparticle compositions for modifying antigen-specific T cells and uses thereof.
    Type: Application
    Filed: April 20, 2022
    Publication date: November 21, 2024
    Inventors: Gabriel A. Kwong, Shreyas Dahotre, Marielena Gamboa, Philip J. Santangelo, Fang-Yi Su, Daryll Vanover
  • Publication number: 20240285760
    Abstract: The present disclosure relates to promoter constructs comprising: one or more heat shock elements: a core promoter; and a gene of interest: vectors comprising the promoter constructs, and immune cells modified to include the promoter constructs. The promoter constructs provide the ability to remotely control immune cell therapies by thermal targeting. The present disclosure also provides methods of use for the promoter constructs.
    Type: Application
    Filed: June 24, 2022
    Publication date: August 29, 2024
    Inventors: Gabriel A. KWONG, Marielena GAMBOA, Ian C. MILLER, Ali ZAMAT
  • Publication number: 20230390335
    Abstract: Disclosed are synthetic antigen chimeric antigen receptor systems and methods of their use for the treatment of cancer.
    Type: Application
    Filed: October 14, 2021
    Publication date: December 7, 2023
    Inventors: Gabriel Kwong, Marielena Gamboa, Ali Zamat, Ji-Ho Park, Heegon Kim, Phillip J. Santangelo, Daryll A. Vanover
  • Publication number: 20200299686
    Abstract: Embodiments of the present disclosure relate generally to compositions and methods for the design of remote controlled biological systems, and more specifically to synthetic bioswitches that provide the ability to non-invasively and remotely control the function and activity of live cells, such as for example and not limitation, the expression of biologically active proteins or biological therapeutics, and the manipulation of physiologic or genetic processes and/or protein expression in live cells, in vivo (including, e.g., at desired anatomical sites) or ex vivo.
    Type: Application
    Filed: October 2, 2018
    Publication date: September 24, 2020
    Inventors: Gabriel A. Kwong, Ian C. Miller, Marielena Gamboa Castro