Patents by Inventor Marielle Engelen

Marielle Engelen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for diagnosing impaired absorption of amino acids, monosaccharides and fatty acids
    Patent number: 10234448
    Abstract: Provided herein are methods for diagnosing impaired nutrient absorption or determining a nutrient absorption level in an individual. A first stable absorption isotopologue of a nutrient and a second stable absorption isotopolog of the same nutrient are administered orally and intravenously, respectively, to the individual. Amounts of the first and second isotopologs are both measured in blood samples drawn periodically and a ratio of the first isotopolog to the second isotopolog is calculated providing a level of nutrient absorption. The results are compared with a healthy control or an ideal value of 1.0. The ratio less than that of a healthy control or significantly lower than 1.0 indicates an impaired nutrient absorption in the individual.
    Type: Grant
    Filed: October 6, 2016
    Date of Patent: March 19, 2019
    Assignee: The Texas A&M University System
    Inventors: Nicolaas E. Deutz, Gerdien C. Ligthart-Melis, Marielle Engelen, Gabriella Ten Have
  • Methods for Diagnosing Impaired Absorption of Amino Acids, Monosaccharides and Fatty Acids
    Publication number: 20170097335
    Abstract: Provided herein are methods for diagnosing impaired nutrient absorption or determining a nutrient absorption level in an individual. A first stable absorption isotopologue of a nutrient and a second stable absorption isotopologue of the same nutrient are administered orally and intravenously, respectively, to the individual. Amounts of the first and second isotopologues are both measured in blood samples drawn periodically and a ratio of the first isotopologue to the second isotopologue is calculated providing a level of nutrient absorption. The results are compared with a healthy control or an ideal value of 1.0. The ratio less than that of a healthy control or significantly lower than 1.0 indicates an impaired nutrient absorption in the individual.
    Type: Application
    Filed: October 6, 2016
    Publication date: April 6, 2017
    Applicant: The Texas A&M University System
    Inventors: Nicolaas E. Deutz, Gerdien C. Ligthart-Melis, Marielle Engelen, Gabriella Ten Have
  • Compositions and methods for improving the condition of patients suffering from copd and other diseases
    Publication number: 20060173079
    Abstract: A food supplement of therapeutic composition is provided suitable for the treatment or prophylaxis of COPD and other acute or chronic diseases in a mammal, especially a human being, comprising at least one of glutamate, other than mono sodium glutamate, and a precursor of glutamate selected from the group consisting of leucine, valine, isoleucine, and a keto acid thereof, in a daily dose for said mammal of at least 6 grams, preferably between 9 and 20 grams, of the total of said glutamate and precursor forms thereof.
    Type: Application
    Filed: January 12, 2004
    Publication date: August 3, 2006
    Applicant: UNIVERSITEIT VAN MAASTRICHT
    Inventors: Marielle Engelen, Nicolaas Deutz, Annemie Schols, Emiel Wouters