Patents by Inventor Marija Plodinec
Marija Plodinec has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20230358724Abstract: The invention relates to a method for classifying a tissue sample obtained from mammary carcinoma. The method comprises determining a stiffness value for each of a plurality of points on said tissue sample, resulting in a stiffness distribution, and assigning said sample to a breast cancer subtype and nodal status based on said stiffness distribution.Type: ApplicationFiled: June 26, 2023Publication date: November 9, 2023Inventors: Marija PLODINEC, Ellen OBERMANN, Philipp OERTLE, Christian RÄZ
-
Patent number: 11686720Abstract: The invention relates to a method for classifying a tissue sample obtained from mammary carcinoma. The method comprises determining a stiffness value for each of a plurality of points on said tissue sample, resulting in a stiffness distribution, and assigning said sample to a breast cancer subtype and nodal status based on said stiffness distribution.Type: GrantFiled: October 24, 2016Date of Patent: June 27, 2023Assignee: UNIVERSITAT BASELInventors: Marija Plodinec, Ellen Obermann, Philipp Oertle, Christian Räz
-
Publication number: 20200253590Abstract: The invention relates to a core biopsy needle (1) for obtaining a tissue sample comprising a hollow outer needle (10) extending along a longitudinal axis (L), and an inner needle (20), which is at least partially arranged or arrangeable within said outer needle along said longitudinal axis (L), wherein said inner needle (20) comprises at least one tissue-holding surface (21), wherein said tissue-holding surface (21) is adapted such that a tissue (3) adheres to the at least one tissue-holding surface (21), when the core biopsy needle (1) is inserted into the tissue (3).Type: ApplicationFiled: October 5, 2018Publication date: August 13, 2020Applicants: UNIVERSITÄT BASEL, ARTIDIS AGInventors: Marija PLODINEC, Ludovit Pavel ZWEIFEL, Philipp Maximillian OERTLE, Armin STUMPP, Marko LOPARIC
-
Publication number: 20180306769Abstract: The invention relates to a method for classifying a tissue sample obtained from mammary carcinoma. The method comprises determining a stiffness value for each of a plurality of points on said tissue sample, resulting in a stiffness distribution, and assigning said sample to a breast cancer subtype and nodal status based on said stiffness distribution.Type: ApplicationFiled: October 24, 2016Publication date: October 25, 2018Applicant: UNIVERSITAT BASELInventors: Marija PLODINEC, Ellen OBERMANN, Philipp OERTLE, Christian RÄZ
-
Publication number: 20170299570Abstract: The invention relates to a method for staging metastatic potential of a primary tumour sample or related lymph node by nanomechanical measurement and/or for determing the reoccurrence or incidence potential.Type: ApplicationFiled: October 5, 2015Publication date: October 19, 2017Applicant: UNIVERSITAT BASELInventors: Marko LOPARIC, Marija PLODINEC, Ellen OBERMANN, Christian RAEZ
-
Patent number: 9500670Abstract: The present invention relates to a method for controlling a scanning probe microscope having a probe (2) with a tip (21) for interacting with a sample (4), and a nanoscanner (1) for retaining the sample (4) or the probe (2), comprising the steps of monitoring the extension of the piezo element (1) along a first direction (R) along which the tip (21) is moved towards the sample (4), and adjusting the level of the probe (2) along the first direction (R) by means of an additional actuator (3), when the nanoscanner (1) exhibits an extension below or above a threshold value. The invention further relates to a device (100) for controlling a scanning probe microscope.Type: GrantFiled: December 12, 2013Date of Patent: November 22, 2016Assignee: UNIVERSITAT BASELInventors: Roderick Lim, Marija Plodinec, Marko Loparic, Pascal Oehler, Leon Camenzind
-
Patent number: 9244095Abstract: The present invention relates to a method for controlling a scanning probe microscope having a probe (2) with a tip (21) for interacting with a sample (4), and a nanoscanner (1) for retaining the sample (4) or the probe (2), comprising the steps of monitoring the extension of the piezo element (1) along a first direction (R) along which the tip (21) is moved towards the sample (4), and adjusting the level of the probe (2) along the first direction (R) by means of an additional actuator (3), when the nanoscanner (1) exhibits an extension below or above a threshold value. The invention further relates to a device (100) for controlling a scanning probe microscope.Type: GrantFiled: December 12, 2012Date of Patent: January 26, 2016Assignee: UNIVERSITAT BASELInventors: Marija Plodinec, Marko Loparic, Roderick Y H Lim
-
Publication number: 20150369838Abstract: The present invention relates to a method for controlling a scanning probe microscope having a probe (2) with a tip (21) for interacting with a sample (4), and a nanoscanner (1) for retaining the sample (4) or the probe (2), comprising the steps of monitoring the extension of the piezo element (1) along a first direction (R) along which the tip (21) is moved towards the sample (4), and adjusting the level of the probe (2) along the first direction (R) by means of an additional actuator (3), when the nanoscanner (1) exhibits an extension below or above a threshold value. The invention further relates to a device (100) for controlling a scanning probe microscope.Type: ApplicationFiled: December 12, 2013Publication date: December 24, 2015Applicant: UNIVERSITAT BASELInventors: Roderick LIM, Marija PLODINEC, Marko LOPARIC, Pascal OEHLER, Leon CAMENZIND
-
Publication number: 20140338073Abstract: The present invention relates to a method for controlling a scanning probe microscope having a probe (2) with a tip (21) for interacting with a sample (4), and a nanoscanner (1) for retaining the sample (4) or the probe (2), comprising the steps of monitoring the extension of the piezo element (1) along a first direction (R) along which the tip (21) is moved towards the sample (4), and adjusting the level of the probe (2) along the first direction (R) by means of an additional actuator (3), when the nanoscanner (1) exhibits an extension below or above a threshold value. The invention further relates to a device (100) for controlling a scanning probe microscope.Type: ApplicationFiled: December 12, 2012Publication date: November 13, 2014Applicant: UNIVERSITAT BASELInventors: Marija Plodinec, Marko Loparic, Roderick YH Lim
-
Patent number: 8756711Abstract: The present invention relates to a method for classifying a tissue biopsy sample obtained from a tumor, comprising determining a plurality of stiffness values for said sample by measuring a plurality of points on the sample with a spatial resolution of at least 100 ?m and assigning the sample to a probability of malignancy. A sample showing a unimodal stiffness distribution is assigned to a high probability of being non-malignant, and a sample showing an at least bimodal stiffness distribution is assigned to a high probability of being malignant, wherein said stiffness distribution is characterized by a first peak exhibiting an at least two-fold higher stiffness value than a second peak. The present invention further relates to a system for classifying a tumor tissue biopsy sample.Type: GrantFiled: December 12, 2011Date of Patent: June 17, 2014Assignee: Universitat BaselInventors: Marija Plodinec, Roderick Lim, Marko Loparic
-
Publication number: 20140007309Abstract: The present invention relates to a method for classifying a tissue biopsy sample obtained from a tumour, comprising determining a plurality of stiffness values for said sample by measuring a plurality of points on the sample with a spatial resolution of at least 100 ?m and assigning the sample to a probability of malignancy. A sample showing a unimodal stiffness distribution is assigned to a high probability of being non-malignant, and a sample showing an at least bimodal stiffness distribution is assigned to a high probability of being malignant, wherein said stiffness distribution is characterized by a first peak exhibiting an at least two-fold higher stiffness value than a second peak. The present invention further relates to a system for classifying a tumour tissue biopsy sample.Type: ApplicationFiled: December 12, 2011Publication date: January 2, 2014Applicant: UNIVERSITAT BASELInventors: Marija Plodinec, Roderick Lim, Marko Loparic