Abstract: A wire clamping and twisting device includes a base member with a radial projection,; an inner member rotatably held in the base member and having a hexagonal shaft engageable by a cordless electric screwdriver to rotate the shaft in the base member, an inner recess for receiving the distal ends of the wires, a plate insert having a V-shaped recess extending into the inner recess, with walls of the plate insert engaging distal ends of the wires to cause the distal ends to rotate with the inner member and thereby twist the wires, and an outer surface with an annular groove which receives the radial projection of the base member for preventing axial movement of the inner member in the base member, while permitting rotation thereof; and a grasping device mounted to the base member for non-rotatably grasping portions of the wires located proximally from the distal ends of the wires during rotation of the inner member, the grasping device having opposed gripping members for gripping the proximally located portions