Patents by Inventor Marijo Kent First

Marijo Kent First has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND KITS FOR DETECTING MUTATIONS
    Publication number: 20090068646
    Abstract: Disclosed are methods and kits for detecting mutations in DNA by comparing the size of an amplified microsatellite locus to the expected size. The methods and kits may used in various applications, including monitoring exposure of a cell or organism to a mutagen, evaluating the mutagenicity of an agent, and evaluating a putative precancerous or cancerous cell or tumor cell for microsatellite instability.
    Type: Application
    Filed: October 24, 2005
    Publication date: March 12, 2009
    Applicant: PROMEGA CORPORATION
    Inventors: Jeffery Bacher, Richard Halberg, Marijo Kent-First, Keith V. Wood
  • Methods and Kits for Detecting Germ Cell Genomic Instability
    Publication number: 20080311565
    Abstract: Disclosed are methods for detecting microsatellite instability in the germ line of males, methods of assessing risk for developing testicular cancer, methods of evaluating the microsatellite stability of putative cancer or precancerous cells or a tumor, methods for evaluating germ cells for exposure to mutagens, and kits for use in the methods of the invention.
    Type: Application
    Filed: October 24, 2005
    Publication date: December 18, 2008
    Applicant: PROMEGA CORPORATION
    Inventors: Marijo Kent-First, Wael Mohamed Abdel Megid, Jeffery Bacher
  • Methods and kits for detecting mutations
    Publication number: 20060088874
    Abstract: Disclosed are, methods and kits for detecting mutations in DNA by comparing the size of an amplified microsatellite locus to the expected size. The methods and kits may used in various applications, including monitoring exposure of a cell or organism to a mutagen, evaluating the mutagenicity of an agent, and evaluating a putative precancerous or cancerous cell or tumor cell for microsatellite instability.
    Type: Application
    Filed: October 24, 2005
    Publication date: April 27, 2006
    Applicant: Promega Corporation
    Inventors: Jeffery Bacher, Richard Halberg, Marijo Kent-First, Keith Wood
  • Male infertility Y-deletion detection battery
    Patent number: 5840549
    Abstract: The present disclosure discloses a method for probing the integrity of a Y chromosome utilizing multiplex PCR reactions which amplify specific regions of the human Y chromosome which have been linked to normal fertility in human males. The method is capable of detecting deletion mutations within the Y chromosome which are predictive of human male infertility. A kit containing reagents needed to practice the method is also disclosed.
    Type: Grant
    Filed: December 4, 1996
    Date of Patent: November 24, 1998
    Assignee: Promega Corporation
    Inventors: Marijo Kent First, Ariege Muallem
  • Male infertility Y-deletion detection battery
    Patent number: 5783390
    Abstract: The present disclosure describes a method for probing the integrity of a Y chromosome utilizing multiplex PCR reactions which amplify specific regions of the human Y chromosome which have been linked to normal fertility in human males. The method is capable of detecting deletion mutations within the Y chromosome which are predictive of human male infertility. A kit containing reagents needed to practice the method is also disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 21, 1998
    Assignee: Promega Corporation
    Inventors: Marijo Kent First, Alexander I. Agoulnik
  • Male infertility y-deletion detection battery
    Patent number: 5776682
    Abstract: The present disclosure describes a method for probing the integrity of a Y chromosome utilizing multiplex PCR reactions which amplify specific regions of the human Y chromosome which have been linked to normal fertility in human males. The method is capable of detecting deletion mutations within the Y chromosome which are predictive of human male infertility. A kit containing reagents needed to practice the method is also disclosed.
    Type: Grant
    Filed: September 18, 1995
    Date of Patent: July 7, 1998
    Assignee: Promega Corporation
    Inventors: Marijo Kent First, Alexander I. Agoulnik, Ariege Muallem