Patents by Inventor Marika G. Rioult

Marika G. Rioult has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STERILIZATION OF SELF-ASSEMBLING PEPTIDES BY IRRADIATION
    Publication number: 20230338613
    Abstract: Gamma ray and e-beam irradiation provided efficient sterilization of certain self-assembling peptides (including RADA16 in solution) without substantial degradation of the major peptide, while, e.g., another self-assembly peptide, QLEL12 was significantly degraded following irradiation. Irradiation sterilization enhances the rheological property of, for example, RADA16 hydrogel once applied to tissue at a physiological pH. The rheological property increase can result in higher efficacy in a variety of biomedical applications.
    Type: Application
    Filed: July 5, 2023
    Publication date: October 26, 2023
    Applicant: 3-D Matrix, Ltd.
    Inventors: Marika G. Rioult, Eun Seok Gil, Elton Aleksi, Naoki Yamamoto
  • JAMMED GEL BIOINK WITH SELF-ASSEMBLING PEPTIDES
    Publication number: 20230323306
    Abstract: A jammed gel bioink comprises a self-assembling peptide solution comprising a self-assembling peptide, and a cell solution comprising living cells and a cell culture medium. The self-assembling peptide solution is extruded to form an object, and then the cell solution is injected into the object. Useful methods of making the jammed gel bioink are also disclosed.
    Type: Application
    Filed: April 5, 2023
    Publication date: October 12, 2023
    Applicants: 3-D Matrix, Ltd., CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE CLAUDE BERNARD LYON 1 (UCBL1), L’ECOLE SUPERIEURE DE CHIMIE, PHYSIQUE, ELECTRONIQUE DE LYON (CPE Lyon)
    Inventors: Christophe A. Marquette, Marie Reveiller Buffier, Marika G. Rioult, Eun Seok Gil
  • BIOINK CONTAINING SELF-ASSEMBLING PEPTIDES
    Publication number: 20230323305
    Abstract: A bioink comprises a cell solution comprising living cells and a cell culture medium, and a self-assembling peptide solution comprising a self-assembling peptide. The bioink is formed by mixing and extruding the cell solution and the self-assembling peptide solution together, and the bioink can be continuously extruded from the mixer after mixing. Useful methods of making bioinks and are also disclosed.
    Type: Application
    Filed: April 5, 2023
    Publication date: October 12, 2023
    Applicants: 3-D Matrix, Ltd., CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE CLAUDE BERNARD LYON 1 (UCBL1), L’ECOLE SUPERIEURE DE CHIMIE, PHYSIQUE, ELECTRONIQUE DE LYON (CPE Lyon)
    Inventors: Christophe A. Marquette, Marie Reveiller Buffier, Marika G. Rioult, Eun Seok Gil
  • Sterilization of self-assembling peptides by irradiation
    Patent number: 11738114
    Abstract: Gamma ray and e-beam irradiation provided efficient sterilization of certain self-assembling peptides (including RADA16 in solution) without substantial degradation of the major peptide, while, e.g., another self-assembly peptide, QLEL12 was significantly degraded following irradiation. Irradiation sterilization enhances the rheological property of, for example, RADA16 hydrogel once applied to tissue at a physiological pH. The rheological property increase can result in higher efficacy in a variety of biomedical applications.
    Type: Grant
    Filed: December 2, 2022
    Date of Patent: August 29, 2023
    Assignee: 3-D Matrix, Ltd.
    Inventors: Marika G. Rioult, Eun Seok Gil, Elton Aleksi, Naoki Yamamoto
  • Sterilization of self-assembling peptides by irradiation
    Patent number: 11738113
    Abstract: Gamma ray and e-beam irradiation provided efficient sterilization of certain self-assembling peptides (including RADA16 in solution) without substantial degradation of the major peptide, while, e.g., another self-assembly peptide, QLEL12 was significantly degraded following irradiation. Irradiation sterilization enhances the rheological property of, for example, RADA16 hydrogel once applied to tissue at a physiological pH. The rheological property increase can result in higher efficacy in a variety of biomedical applications.
    Type: Grant
    Filed: November 6, 2022
    Date of Patent: August 29, 2023
    Assignee: 3-D Matrix, Ltd.
    Inventors: Marika G. Rioult, Eun Seok Gil, Elton Aleksi, Naoki Yamamoto
  • STERILIZATION OF SELF-ASSEMBLING PEPTIDES BY IRRADIATION
    Publication number: 20230149598
    Abstract: Gamma ray and e-beam irradiation provided efficient sterilization of certain self-assembling peptides (including RADA16 in solution) without substantial degradation of the major peptide, while, e.g., another self-assembly peptide, QLEL12 was significantly degraded following irradiation. Irradiation sterilization enhances the rheological property of, for example, RADA16 hydrogel once applied to tissue at a physiological pH. The rheological property increase can result in higher efficacy in a variety of biomedical applications.
    Type: Application
    Filed: November 6, 2022
    Publication date: May 18, 2023
    Applicant: 3-D Matrix, Ltd.
    Inventors: Marika G. Rioult, Eun Seok Gil, Elton Aleksi, Naoki Yamamoto
  • STERILIZATION OF SELF-ASSEMBLING PEPTIDES BY IRRADIATION
    Publication number: 20230149599
    Abstract: Gamma ray and e-beam irradiation provided efficient sterilization of certain self-assembling peptides (including RADA16 in solution) without substantial degradation of the major peptide, while, e.g., another self-assembly peptide, QLEL12 was significantly degraded following irradiation. Irradiation sterilization enhances the rheological property of, for example, RADA16 hydrogel once applied to tissue at a physiological pH. The rheological property increase can result in higher efficacy in a variety of biomedical applications.
    Type: Application
    Filed: December 2, 2022
    Publication date: May 18, 2023
    Applicant: 3-D Matrix, Ltd.
    Inventors: Marika G. Rioult, Eun Seok Gil, Elton Aleksi, Naoki Yamamoto
  • Sterilization of self-assembling peptides by irradiation
    Patent number: 11534528
    Abstract: Gamma ray and e-beam irradiation provided efficient sterilization of certain self-assembling peptides (including RADA16 in solution) without substantial degradation of the major peptide, while, e.g., another self-assembly peptide, QLEL12 was significantly degraded following irradiation. Irradiation sterilization enhances the rheological property of, for example, RADA16 hydrogel once applied to tissue at a physiological pH. The rheological property increase can result in higher efficacy in a variety of biomedical applications.
    Type: Grant
    Filed: March 30, 2021
    Date of Patent: December 27, 2022
    Assignee: 3-D Matrix, Ltd.
    Inventors: Marika G. Rioult, Eun Seok Gil, Elton Aleksi, Naoki Yamamoto
  • STERILIZATION OF SELF-ASSEMBLING PEPTIDES BY IRRADIATION
    Publication number: 20210299326
    Abstract: Gamma ray and e-beam irradiation provided efficient sterilization of certain self-assembling peptides (including RADA16 in solution) without substantial degradation of the major peptide, while, e.g., another self-assembly peptide, QLEL12 was significantly degraded following irradiation. Irradiation sterilization enhances the rheological property of, for example, RADA16 hydrogel once applied to tissue at a physiological pH. The rheological property increase can result in higher efficacy in a variety of biomedical applications.
    Type: Application
    Filed: March 30, 2021
    Publication date: September 30, 2021
    Applicant: 3-D Matrix, Ltd.
    Inventors: Marika G. Rioult, Eun Seok Gil, Elton Aleksi, Naoki Yamamoto