Patents by Inventor Marika Karkkainen

Marika Karkkainen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treatment for lymphedema comprising administering a polynucleotide encoding VEGF-D
    Patent number: 8357669
    Abstract: The present invention provides materials and methods for screening for and treating hereditary lymphedema in human subjects.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: January 22, 2013
    Assignees: Vegenics Pty Limited, University of Pittsburgh—of the Commonwealth System of Higher Education
    Inventors: Robert E. Ferrell, Kari Alitalo, David N. Finegold, Marika Karkkainen
  • SCREENING AND THERAPY FOR LYMPHATIC DISORDERS INVOLVING THE FLT4 RECEPTOR TYROSINE KINASE (VEGFR-3)
    Publication number: 20120010276
    Abstract: The present invention provides materials and methods for screening for and treating hereditary lymphedema in human subjects.
    Type: Application
    Filed: September 23, 2011
    Publication date: January 12, 2012
    Applicants: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION, VEGENICS PTY LTD
    Inventors: ROBERT E. FERRELL, Kari Alitalo, David N. Finegold, Marika Karkkainen
  • Screening and Therapy for Lymphatic Disorders Involving the FLT4 Receptor Tyrosine Kinase (VEGFR-3)
    Publication number: 20110065636
    Abstract: The present invention provides materials and methods for screening for and treating hereditary lymphedema in human subjects.
    Type: Application
    Filed: November 6, 2010
    Publication date: March 17, 2011
    Inventors: Robert E. Ferrell, Kari Alitalo, David N. Finegold, Marika Karkkainen
  • Method of treating lymphedema comprising administering VEGF-D
    Patent number: 7829536
    Abstract: The present invention provides materials and methods for screening for and treating hereditary lymphedema in human subjects.
    Type: Grant
    Filed: February 5, 2009
    Date of Patent: November 9, 2010
    Assignees: Vegenics Limited, University of Pittsburgh of the Commonwealth System of Higher Education
    Inventors: Robert E. Ferrell, Kari Alitalo, David N. Finegold, Marika Karkkainen
  • Use of VEGF-C or VEGF-D in Reconstructive Surgery
    Publication number: 20100041605
    Abstract: The present invention provides materials and methods for repairing tissue and using vascular endothelial growth factor C (VEGF-C) genes and/or proteins. Methods and materials related to the use of VEGF-C for the reduction of edema and improvement of skin perfusion is provided. Also provided is are materials and methods for using VEGF-C before, during, and after reconstructive surgery.
    Type: Application
    Filed: June 23, 2009
    Publication date: February 18, 2010
    Applicant: Vegenics Limited
    Inventors: Kari Alitalo, Anne Saaristo, Marika Karkkainen, Tuomas Tammela, Sirpa Asko-Seljavaara, Seppo Yla-Herttuala, Yulong He
  • SCREENING AND THERAPY FOR LYMPHATIC DISORDERS INVOLVING THE FLT4 RECEPTOR TYROSINE KINASE (VEGFR-3)
    Publication number: 20090191166
    Abstract: The present invention provides materials and methods for screening for and treating hereditary lymphedema in human subjects.
    Type: Application
    Filed: February 5, 2009
    Publication date: July 30, 2009
    Inventors: Robert E. Ferrell, Kari Alitalo, David N. Finegold, Marika Karkkainen
  • Neuropilin/VEGF-C/VEGFR-3 Materials and Methods
    Publication number: 20080241142
    Abstract: The present invention relates to identifying modulators of VEGF-C or VEGF-D ligand binding to the nervous system transmembrane protein neuropilin-2 and materials and methods for detecting said modulators.
    Type: Application
    Filed: November 29, 2007
    Publication date: October 2, 2008
    Applicant: LICENTIA LTD.
    Inventors: Kari Alitalo, Marika Karkkainen, Kaisa Karila
  • Use of VEGF-C or VEGF-D in Reconstructive Surgery
    Publication number: 20080147045
    Abstract: The present invention provides materials and methods for repairing tissue and using vascular endothelial growth factor C (VEGF-C) genes and/or proteins. Methods and materials related to the use of VEGF-C for the reduction of edema and improvement of skin perfusion is provided. Also provided is are materials and methods for using VEGF-C before, during, and after reconstructive surgery.
    Type: Application
    Filed: July 24, 2007
    Publication date: June 19, 2008
    Applicants: Licentia Ltd., Ludwig Institute for Cancer Research
    Inventors: Kari Alitalo, Anne Saaristo, Marika Karkkainen, Tuomas Tammela, Sirpa Asko-Seljavaara, Seppo Yla-Herttuala, Yulong He
  • Vegf-C or Vegf-D Materials and Methods for Stimulation of Neural Stem cells
    Publication number: 20080057028
    Abstract: The present invention relates to VEGF-C or VEGF-D materials and methods for promoting growth and differentiation of neural stem cells, neuronal and neuronal precursor cells, oligodendrocytes and oligodendrocyte precursor cells and materials and methods for administering said cells to inhibit neuropathology.
    Type: Application
    Filed: September 23, 2004
    Publication date: March 6, 2008
    Applicants: INSTITUTE NATIONALE DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Kari Alitalo, Marika Karkkainen, Paula Haiko, Kirsi Sainio, Kirmo Wartiovaara, Jean L. Thomas, Anne Eichmann
  • Screening and Therapy for Lymphatic Disorders Involving the FLT4 Receptor Tyrosine Kinase (VEGFR-3)
    Publication number: 20070141609
    Abstract: The present invention provides materials and methods for screening for and treating hereditary lymphedema in human subjects.
    Type: Application
    Filed: January 3, 2007
    Publication date: June 21, 2007
    Applicants: Ludwig Institute for Cancer Research, Licentia, University of Pittsburgh
    Inventors: Robert Ferrell, Kari Alitalo, David Finegold, Marika Karkkainen
  • VEGF-C or VEGF-D materials and methods for treatment of neuropathologies
    Publication number: 20070082848
    Abstract: The present invention relates to VEGF-C or VEGF-D materials and methods for promoting growth and differentiation of neural stem cells and materials and methods for administering said cells to inhibit neuropathology.
    Type: Application
    Filed: November 16, 2006
    Publication date: April 12, 2007
    Applicant: LICENTIA LTD.
    Inventors: Kari Alitalo, Marika Karkkainen, Paula Haiko, Kirsi Sainio, Kirmo Wartiovaara
  • Use of VEGF-C or VEGF-D in reconstructive surgery
    Publication number: 20050043235
    Abstract: The present invention provides materials and methods for repairing tissue and using vascular endothelial growth factor C (VEGF-C) genes and/or proteins. Methods and materials related to the use of VEGF-C for the reduction of edema and improvement: of skin perfusion is provided. Also provided is are materials and methods for using VEGF-C before, during, and after reconstructive surgery.
    Type: Application
    Filed: June 14, 2004
    Publication date: February 24, 2005
    Inventors: Kari Alitalo, Anne Saaristo, Marika Karkkainen, Tuomas Tammela, Sirpa Asko-Seljavaara, Seppo Yla-Herttuala, Yulong He
  • VEGF-C or VEGF-D materials and methods for treatment of neuropathologies
    Publication number: 20040214766
    Abstract: The present invention relates to VEGF-C or VEGF-D materials and methods for promoting growth and differentiation of neural stem cells and materials and methods for administering said cells to inhibit neuropathology.
    Type: Application
    Filed: September 23, 2003
    Publication date: October 28, 2004
    Inventors: Kari Alitalo, Marika Karkkainen, Paula Haiko, Kirsi Sainio, Kirmo Wartiovaara
  • Screening for lymphatic disorders involving the FLT4 receptor tyrosine kinase (VEGFR-3)
    Patent number: 6764820
    Abstract: The present invention provides materials and methods for screening for and treating hereditary lymphedema in human subjects.
    Type: Grant
    Filed: August 16, 1999
    Date of Patent: July 20, 2004
    Assignees: Ludwig Institute for Cancer Research, Licentia, Ltd., University of Pittsburgh-of the Commonwealth System of Higher Education
    Inventors: Robert E. Ferrell, Kari Alitalo, David N. Finegold, Marika Karkkainen
  • Screening and therapy for lymphatic disorders involving the FLT4 receptor tyrosine kinase (VEGFR-3)
    Publication number: 20040063656
    Abstract: The present invention provides materials and methods for screening for and treating hereditary lymphedema in human subjects.
    Type: Application
    Filed: September 12, 2003
    Publication date: April 1, 2004
    Inventors: Robert E. Ferrell, Kari Alitalo, David N. Finegold, Marika Karkkainen
  • Neuropilin/VEGF-C/VEGFR-3 materials and methods
    Publication number: 20030113324
    Abstract: The present invention relates to identifying modulators of VEGF-C or VEGF-D ligand binding to the nervous system transmembrane protein neuropilin-2 and materials and methods for detecting said modulators.
    Type: Application
    Filed: September 30, 2002
    Publication date: June 19, 2003
    Inventors: Kari Alitalo, Marika Karkkainen, Kaisa Karila
  • SCREENING AND THERAPY FOR LYMPHATIC DISORDERS INVOLVING THE FLT4 RECEPTOR TYROSINE KINASE (VEGFR-3)
    Publication number: 20030026759
    Abstract: The present invention provides materials and methods for screening for and treating hereditary lymphedema in human subjects.
    Type: Application
    Filed: August 16, 1999
    Publication date: February 6, 2003
    Inventors: ROBERT E. FERRELL, KARI ALITALO, DAVID N. FINEGOLD, MARIKA KARKKAINEN