Abstract: A blood sugar condition is estimated by measuring a urine sugar value, discriminating whether it is less than a discriminating method classification boundary value, when it is less, obtaining an averaged value of measured urine sugar values during a past predetermined period of time, measured at the same time of day as the latest measurement, calculating the difference between the averaged and measured urine sugar values, when the difference is not less than a positive discriminating reference difference, discriminating as being a blood sugar value decrease, when the measured value is not less than the discriminating method classification boundary value, obtaining an averaged value of all measured values during the past predetermined period of time, calculating a ratio between the measured and averaged values, and, when the ratio is not greater than a first discriminating reference ratio, discriminating as being the blood sugar value decrease.

Abstract: A blood sugar condition is estimated by (1) measuring a urine sugar value A, (2) discriminating whether or not the measured urine sugar value is less than a discriminating method classification boundary value, (3) when it is less, obtaining an averaged value X of measured urine sugar values during a past predetermined period of time, measured at the same timing in a one-day life as the timing when the latest measured urine sugar value is measured, (4) calculating the difference between the averaged value and the measured urine sugar value, (5) when the difference is not less than a positive discriminating reference difference, discriminating as being a blood sugar value decrease, (6) when the measured urine sugar value A is not less than the discriminating method classification boundary value, obtaining an averaged value X of all measured urine sugar values during the past predetermined period of time, (7) calculating a ratio between the measured urine sugar value and the averaged value X, and, (8) when the r

Abstract: A practical measuring device and a measuring method that allow simply measuring average postprandial blood glucose from urinary glucose. The blood glucose measuring device includes a measuring unit that measures postprandial urinary glucose from subject's urine at a predetermined time after meal, a processing unit that calculates average postprandial blood glucose through a period up to the predetermined time after meal, based on the postprandial urinary glucose, a storage unit that stores calibration data including the postprandial urinary glucose and the average postprandial blood glucose in association, and an output unit that outputs data indicating the calculated average postprandial blood glucose. The processing unit calculates the average postprandial blood glucose, based on the postprandial urinary glucose from the urine of the subject who has intaken a desired amount of water or perspired in the period up to the predetermined time after meal, and the calibration data.

Abstract: A biosensor and a biosensor measuring apparatus whose performance can be easily determined by an ordinary user are provided. A biosensor 100 includes a substrate 1 having a quality deciding section 13 and a sample receiving section 15 provided on the substrate 1 to which a sample is supplied. The quality deciding section 13 includes a moisture absorbing material changed in color through absorption of moisture. The sample receiving section 15 has a reagent section 7 including an enzyme reacted with a test substance as a substrate. The quality deciding section 13 includes a recess 17 formed in the substrate 1, the moisture absorbing material 16 disposed in the recess 17 and a film 18 with no air permeability substantially covering the opening of the recess 17 and closely adhered to the moisture absorbing material 16. Cobalt salt is used as the moisture absorbing material 16.

Abstract: A practical measuring device and a measuring method that allow simply measuring average postprandial blood glucose from urinary glucose. The blood glucose measuring device includes a measuring unit that measures postprandial urinary glucose from subject's urine at a predetermined time after meal, a processing unit that calculates average postprandial blood glucose through a period up to the predetermined time after meal, based on the postprandial urinary glucose, a storage unit that stores calibration data including the postprandial urinary glucose and the average postprandial blood glucose in association, and an output unit that outputs data indicating the calculated average postprandial blood glucose. The processing unit calculates the average postprandial blood glucose, based on the postprandial urinary glucose from the urine of the subject who has intaken a desired amount of water or perspired in the period up to the predetermined time after meal, and the calibration data.

Abstract: A blood sugar condition is estimated by (1) measuring a urine sugar value A, (2) discriminating whether or not the measured urine sugar value is less than a discriminating method classification boundary value, (3) when it is less, obtaining an averaged value X of measured urine sugar values during a past predetermined period of time, measured at the same timing in a one-day life as the timing when the latest measured urine sugar value is measured, (4) calculating the difference between the averaged value and the measured urine sugar value, (5) when the difference is not less than a positive discriminating reference difference, discriminating as being a blood sugar value decrease, (6) when the measured urine sugar value A is not less than the discriminating method classification boundary value, obtaining an averaged value X of all measured urine sugar values during the past predetermined period of time, (7) calculating a ratio between the measured urine sugar value and the averaged value X, and, (8) when the r

Abstract: A biosensor capable of measuring the concentration of one or more specific substances in one or more sample solutions almost simultaneously is provided. The biosensor comprises a plurality of sensor units, and each of the sensor units comprises an electrode system including a working electrode and a counter electrode on an insulating base plate and a reagent system including an oxidoreductase and an electron mediator. The biosensor is so configured that sample solutions supplied to the respective sensor units reach the respective reagent systems at different times. Specifically, each of the sensor units has a controlling system between a sample supply inlet and the reagent system, and the controlling system controls the time it takes for the sample solution to reach the reagent system from the sample supply inlet.

Abstract: An adaptor for body fluid measurement of the present invention includes a puncture instrument holding section for detachably carrying a puncture instrument for protruding a puncture needle and a measuring instrument holding section for detachably carrying a measuring instrument for analyzing body fluid with a biosensor, the biosensor being attached to the measuring instrument and having a body fluid supply part to which body fluid is supplied. With use of the adaptor, the body fluid can be measured easily and speedily with the puncture instrument and the measuring instrument attached thereto, which are independent from each other. The present invention further provides a measuring instrument including a puncture instrument holding section.

Abstract: The present invention relates to a biological component measurement apparatus set, in which a puncture mechanism for puncturing skin of a subject to collect a sample blood is integrated with a biosensor measurement apparatus. The puncture mechanism includes a puncture needle, and a cap which is detachably engaged with a body of the apparatus, wherein the cap has a skin contact surface which is brought into contact with the skin for puncturing. The skin contact surface having an opening through which the puncture needle moves to puncture the skin, and is shaped so as to fit a surface shape of the skin to be punctured. The set includes a plurality of different caps each corresponding to a different sample collection site so that a plurality of different sample collection sites can be selected.

Abstract: A biosensor and a biosensor measuring apparatus whose performance can be easily determined by an ordinary user are provided. A biosensor 100 includes a substrate 1 having a quality deciding section 13 and a sample receiving section 15 provided on the substrate 1 to which a sample is supplied. The quality deciding section 13 includes a moisture absorbing material changed in color through absorption of moisture. The sample receiving section 15 has a reagent section 7 including an enzyme reacted with a test substance as a substrate. The quality deciding section 13 includes a recess 17 formed in the substrate 1, the moisture absorbing material 16 disposed in the recess 17 and a film 18 with no air permeability substantially covering the opening of the recess 17 and closely adhered to the moisture absorbing material 16. Cobalt salt is used as the moisture absorbing material 16.

Abstract: In biosensor system 1, biosensor 2 is mounted in measuring apparatus 3 for quantifying or detecting existence of a targeted substrate in a sample solution. Mounting end portion 20 of biosensor 2 to be mounted in measuring apparatus 3 has an extension of one base plate in the length direction, and further extensions of the other base plate in the width direction. Sensor mounting portion 30 of measuring apparatus 3 has a shape matching up with the shape of mounting end portion 20. Thereby wrong insertion of biosensor 2 in measuring apparatus 3 can be prevented. Further, varying shapes of plural biosensors 5 and 6 to have a common part and a non-common part, such biosensors can be handily measured by one measuring apparatus 7.

Abstract: In biosensor system 1, biosensor 2 is mounted in measuring apparatus 3 for quantifying or detecting existence of a targeted substrate in a sample solution. Mounting end portion 20 of biosensor 2 to be mounted in measuring apparatus 3 has an extension of one base plate in the length direction, and further extensions of the other base plate in the width direction. Sensor mounting portion 30 of measuring apparatus 3 has a shape matching up with the shape of mounting end portion 20. Thereby wrong insertion of biosensor 2 in measuring apparatus 3 can be prevented. Further, varying shapes of plural biosensors 5 and 6 to have a common part and a non-common part, such biosensors can be handily measured by one measuring apparatus 7.

Abstract: There are provided a measuring device for a biosensor, capable of performing a simple, accurate and short-time measurement of a specific substance in a sample without being affected by physical properties of a sample, and a measuring method. In the measuring device for a biosensor in accordance with the present invention, a biosensor is used which includes: a sample supply port; an electrode system having a measurement electrode and a counter electrode; and a portion where a sample can be irradiated with light in at least part of a sample supply pathway, to detect electrical and optical variations in the sample and determine a physical factor of the sample, so that a measurement value can be corrected.

Abstract: The present invention relates to a biological component measurement apparatus set, in which a puncture mechanism for puncturing skin of a subject to collect a sample blood is integrated with a biosensor measurement apparatus, wherein the puncture mechanism comprises at least: a puncture needle; and a cap which is detachably engaged with a body of the apparatus, wherein the cap has a skin contact surface which is brought into contact with the skin for puncturing, the skin contact surface having an opening through which the puncture needle moves to puncture the skin, and being shaped so as to fit a surface shape of the skin to be punctured, and the set comprises a plurality of different such caps each corresponding to a different sample collection site so that a plurality of different sample collection sites can be selected.

Abstract: A sample solution treating instrument is provided for facilitating rapid and simplified adjustment of the condition of a sample solution proper for analysis with a biosensor before supplying the solution to the biosensor. The sample solution treating instrument includes, for example, a catalyst or an adsorbent which can remove any interfering substance in order to adjust the sample solution for measurement with a biosensor.

Abstract: There is provided: a sensor capable of accurately and simply measuring LDL cholesterol by only a one-time supply of a sample; and a method of the above measurement. The biosensor is constituted such that cholesterol esterase, cholesterol oxidase or cholesterol dehydrogenase, a reagent for bringing a selective enzyme reaction with LDL, peroxidase, and a dye source, are carried on a substrate.

Abstract: An adaptor for body fluid measurement of the present invention includes a puncture instrument holding section for detachably carrying a puncture instrument for protruding a puncture needle and a measuring instrument holding section for detachably carrying a measuring instrument for analyzing body fluid with a biosensor, the biosensor being attached to the measuring instrument and having a body fluid supply part to which body fluid is supplied. With use of the adaptor, the body fluid can be measured easily and speedily with the puncture instrument and the measuring instrument attached thereto, which are independent from each other. The present invention further provides a measuring instrument including a puncture instrument holding section.

Abstract: A biosensor capable of measuring the concentration of one or more specific substances in one or more sample solutions almost simultaneously is provided. The biosensor comprises a plurality of sensor units, and each of the sensor units comprises an electrode system including a working electrode and a counter electrode on an insulating base plate and a reagent system including an oxidoreductase and an electron mediator. The biosensor is so configured that sample solutions supplied to the respective sensor units reach the respective reagent systems at different times. Specifically, each of the sensor units has a controlling system between a sample supply inlet and the reagent system, and the controlling system controls the time it takes for the sample solution to reach the reagent system from the sample supply inlet.

Abstract: The present invention provides a sample solution treating instrument facilitating rapid and simplified adjustment of the condition of a sample solution proper for analysis with a biosensor before supply to the biosensor. The sample solution treating instrument in accordance with the present invention comprises control means, such as a catalyst or an adsorbent, for example, which can remove any interfering substance for adjusting the sample solution proper for measurement with a biosensor.

Abstract: A biosensor for rapid quantification of a specific component contained in various biological samples with high accuracy has an electrically insulating base, an electrode system including a working electrode and a counter electrode formed on one face of the insulating base, and a reaction layer formed on the insulating base in close contact with the electrode system. The reaction layer contains at least a hydrophilic polymer, a buffer and an enzyme which is separated from the buffer.