Abstract: A simulation system stores information representing a plurality of scenarios of index vectors generated by simulation and a plurality of clusters in which the index vectors in each of a plurality of time steps are classified, classifies the clusters of a final time step of the plurality of scenarios into a plurality of groups, calculates a transition probability at which the index vectors belonging to the cluster in the time step transition to each group in the final time step for each of combinations of the time steps and the clusters and a cluster in which the index vectors belonging to the cluster in the time step are transmissible in a subsequent step, and displays the transition probability and the transmissible cluster.

Abstract: The present disclosure relates to methods of treating rheumatoid arthritis, chronic spontaneous urticaria, and systemic lupus erythematosus using fenebrutinib, an inhibitor of Bruton's tyrosine kinase, or a pharmaceutically acceptable salt thereof.

Abstract: The present invention is a method for producing a polyamide resin, wherein a nylon salt obtained from a dicarboxylic acid and a diamine having a boiling point exceeding 100° C. is heated to be polymerized under normal pressure while water vapor is being allowed to be present in the polymerization reaction system.

Abstract: Disclosed is a method for producing a nylon salt powder, wherein in the production of a nylon salt powder by allowing a dicarboxylic acid powder to react, the content of water is regulated to be 5% by mass or less in relation to the total amount of the dicarboxylic acid powder and a diamine, the dicarboxylic acid powder is beforehand heated to a temperature equal to or higher than melting point of the diamine and equal to or lower than the melting point of the dicarboxylic acid, and while this heating temperature is being maintained, the diamine is added to the dicarboxylic acid powder in such a way that the dicarboxylic acid powder maintains the condition of being in powder form.

Abstract: A semi-aromatic polyamide including an aromatic dicarboxylic acid component, an aliphatic diamine component and a monocarboxylic acid component and having a melting point of 300° C. or higher, wherein the monocarboxylic acid component includes a monocarboxylic acid having a molecular weight of 140 or more, and the content of the monocarboxylic acid component is 1 to 8% by mass.

Abstract: The present invention is a method for producing a polyamide resin, wherein a nylon salt obtained from a dicarboxylic acid and a diamine having a boiling point exceeding 100° C. is heated to be polymerized under normal pressure while water vapor is being allowed to be present in the polymerization reaction system.

Abstract: Disclosed is a method for producing a nylon salt powder, wherein in the production of a nylon salt powder by allowing a dicarboxylic acid powder to react, the content of water is regulated to be 5% by mass or less in relation to the total amount of the dicarboxylic acid powder and a diamine, the dicarboxylic acid powder is beforehand heated to a temperature equal to or higher than melting point of the diamine and equal to or lower than the melting point of the dicarboxylic acid, and while this heating temperature is being maintained, the diamine is added to the dicarboxylic acid powder in such a way that the dicarboxylic acid powder maintains the condition of being in powder form.

Abstract: The semiaromatic polyamide of the present invention includes a terephthalic acid component and a diamine component, wherein the diamine component is any of 1,8-octanediamine, 1,10-decanediamine and 1,12-dodecanediamine, and the proportion of the triamine unit in relation to the diamine unit in the polyamide is 0.3 mol % or less.