Abstract: An objective is to provide an absorbent article that can prevent backflow and can reduce water retention in a front sheet as much as possible. In an incontinence pad 1 for use with a medium or larger volume that absorbs 20 cc or a larger volume of urine, a front sheet 3 is formed by coating a water repellent on a spunlace nonwoven fabric that is made of 100 wt. % of cotton fiber.

Abstract: In an absorbent article for incontinence using cotton fiber for a front-surface sheet, a diffusing range of liquid in the front-surface sheet is made to be a predetermined range or less, thereby eliminating a sticky feeling of the surface, and reducing water retention of the front-surface sheet so as to cause urine to diffuse in the front-surface sheet rapidly.

Abstract: [Problem] To prevent separation and accompanying tearing of a front-surface sheet when non-heat-fusible fibers are used in the front-surface sheet. [Solution] An absorber 4 is interposed between a front-surface sheet 3 and a back-surface sheet 2, and side sheets 7 are disposed on both side portions along the longitudinal direction. The front-surface sheet 3 contains non-heat-fusible fibers, and the side sheets 7 contain a heat-fusible resin. The front-surface sheet 3 is interposed between the laminated side sheets 7 on the outer side in the width direction than the absorber 4 whereby a side flap portion SF in which the side sheet 7, the front-surface sheet 3, the side sheet 7, and the back-surface sheet 2 are laminated in that order from the skin side is formed. A fusing portion 10 in which the sheets forming the side flap portion SF are integrally heat-fused is provided in a region of the side flap portion SF including at least the front and back ends of a sanitary napkin 1.

Abstract: A water repellent is applied to a spun lace nonwoven fabric in which a surface sheet comprises 100% by weight of cotton fibers, and a large number of openings that penetrate the obverse and reverse surfaces are formed in at least a portion that corresponds to an excretory opening. A heat-fusible fiber sheet is disposed adjacent to the absorber side surface of the surface sheet. A plurality of adhesive portions are formed between the surface sheet and the heat-fusible fiber sheet along the longitudinal direction and spaced apart in the widthwise direction of an incontinence pad. A compressed groove recessed from the outer surface of the surface sheet toward the absorber is formed close to the adhesive portions.

Abstract: An absorbent article that prevents back flow and that uses cotton fibers in the surface sheet. The absorbent article is an incontinence pad having at least a medium volume for absorbing at least 20 cc of urine. A surface sheet is formed by coating, with a water-repellent, a spunlace non-woven fabric comprising 100 wt % of cotton fibers. The skin-facing surface side is provided with: a plurality of protrusions that extend along the longitudinal direction of the incontinence pad and are formed with gaps therebetween in the widthwise direction; and a plurality of recesses that extend along the longitudinal direction of the incontinence pad and are formed between adjacent protrusions. The recesses are formed thinner than the protrusions. A plurality of openings, which penetrate the incontinence pad from the front to the rear thereof, is formed along the recesses in at least a section (H) corresponding to an excretory opening.

Abstract: An objective is to provide an absorbent article that can prevent backflow and can reduce water retention in a front sheet as much as possible. In an incontinence pad 1 for use with a medium or larger volume that absorbs 20 cc or a larger volume of urine, a front sheet 3 is formed by coating a water repellent on a spunlace nonwoven fabric that is made of 100 wt. % of cotton fiber.

Abstract: To provide an absorbent article that uses a cotton fiber in a front-surface sheet, prevents rebounding, improves an absorption speed, and reduces a diffusion range of urine in the front-surface sheet. An incontinence pad 1 having a medium or larger volume that absorbs 20 cc or a larger volume of urine is provided. A front-surface sheet 3 is a spunlace nonwoven fabric made of 100% cotton fiber by weight, is coated with a water repellent agent and has many front-face/back-face penetrating openings 10 in a region containing a part corresponding to an excreting hole. The absorber is made of a pulp fiber that does not contain synthetic fiber and a superabsorbent polymer, a basis weight of the pulp fiber being 75 to 300 g/m2, a basis weight of the superabsorbent polymer being 85 to 185 g/m2, and a ratio of the pulp fiber and the superabsorbent polymer being pulp fiber:superabsorbent polymer=70 to 30% by weight:30 to 70% by weight.

Abstract: An absorber 4 is interposed between a front-surface sheet 3 and a back-surface sheet 2, and side sheets 7 are respectively disposed along a longitudinal direction on both side parts of a skin side. The front-surface sheet 3 contains non-thermally fusible fiber, and the back-surface sheet 2 and the side sheets 7 contain thermally fusible resin. Fusion parts 10 allowing the side sheets 7 and the back-surface sheet 2 to be thermally fused under a state of the front-surface sheet 3 interposed therebetween are arranged in areas corresponding to side parts outer than the absorber 4 in a width direction, and the areas include the front-surface sheet 3 interposed between the side sheets 7 and the back-surface sheet 2, and include at least front and back end parts of a sanitary napkin 1. The front-surface sheet is prevented from delaminating and tearing accompanied therewith when non-thermally fusible fiber is used in the front-surface sheet.

Abstract: There is provided an absorbent article with its front-surface sheet composed of cotton fibers by which liquid reversion is prevented and water retention on the front-surface sheet is minimized. An incontinence pad 1 is provided that is configured to absorb urine at medium or more volume that is 20 cc or more. A front-surface sheet 3 is formed of a spunlace nonwoven fabric 100 wt % of which is composed of cotton fibers and which is coated with a water repellent agent, and has, at least at a portion corresponding to an excreting hole, numerous front-face/back-face penetrating openings 10 that are longer shaped in the longitudinal direction of the incontinence pad 1.

Abstract: In an absorbent article for incontinence using cotton fiber for a front-surface sheet, a diffusing range of liquid in the front-surface sheet is made to be a predetermined range or less, thereby eliminating a sticky feeling of the surface, and reducing water retention of the front-surface sheet so as to cause urine to diffuse in the front-surface sheet rapidly.

Abstract: A water repellent is applied to a spun lace nonwoven fabric in which a surface sheet comprises 100% by weight of cotton fibers, and a large number of openings that penetrate the obverse and reverse surfaces are formed in at least a portion that corresponds to an excretory opening. A heat-fusible fiber sheet is disposed adjacent to the absorber side surface of the surface sheet. A plurality of adhesive portions are formed between the surface sheet and the heat-fusible fiber sheet along the longitudinal direction and spaced apart in the widthwise direction of an incontinence pad. A compressed groove recessed from the outer surface of the surface sheet toward the absorber is formed close to the adhesive portions.

Abstract: An absorbent article that prevents back flow and that uses cotton fibers in the surface sheet. The absorbent article is an incontinence pad having at least a medium volume for absorbing at least 20 cc of urine. A surface sheet is formed by coating, with a water-repellent, a spunlace non-woven fabric comprising 100 wt % of cotton fibers. The skin-facing surface side is provided with: a plurality of protrusions that extend along the longitudinal direction of the incontinence pad and are formed with gaps therebetween in the widthwise direction; and a plurality of recesses that extend along the longitudinal direction of the incontinence pad and are formed between adjacent protrusions. The recesses are formed thinner than the protrusions. A plurality of openings, which penetrate the incontinence pad from the front to the rear thereof, is formed along the recesses in at least a section (H) corresponding to an excretory opening.

Abstract: There is provided an absorbent article with its front-surface sheet composed of cotton fibers by which liquid reversion is prevented and water retention on the front-surface sheet is minimized. An incontinence pad 1 is provided that is configured to absorb urine at medium or more volume that is 20 cc or more. A front-surface sheet 3 is formed of a spunlace nonwoven fabric 100 wt % of which is composed of cotton fibers and which is coated with a water repellent agent, and has, at least at a portion corresponding to an excreting hole, numerous front-face/back-face penetrating openings 10 that are longer shaped in the longitudinal direction of the incontinence pad 1.

Abstract: To provide an absorbent article that uses a cotton fiber in a front-surface sheet, prevents rebounding, improves an absorption speed, and reduces a diffusion range of urine in the front-surface sheet. An incontinence pad 1 having a medium or larger volume that absorbs 20 cc or a larger volume of urine is provided. A front-surface sheet 3 is a spunlace nonwoven fabric made of 100% cotton fiber by weight, is coated with a water repellent agent and has many front-face/back-face penetrating openings 10 in a region containing a part corresponding to an excreting hole. The absorber is made of a pulp fiber that does not contain synthetic fiber and a superabsorbent polymer, a basis weight of the pulp fiber being 75 to 300 g/m2, a basis weight of the superabsorbent polymer being 85 to 185 g/m2, and a ratio of the pulp fiber and the superabsorbent polymer being pulp fiber:superabsorbent polymer=70 to 30% by weight:30 to 70% by weight.

Abstract: This invention relates to TAFI inhibitors and their use to enhance myocardial reperfusion and facilitate percutaneous coronary intervention (PCI) in the treatment of acute ST elevation myocardial infarction (STEMI).

Abstract: The invention relates to TAFI inhibitors and their use to treat pulmonary fibrosis.

Abstract: The present invention relates to the design, production and use of analogs of thrombomodulin (TM) that have the ability to enhance the thrombin-mediated activation of protein C but which have a significantly reduced ability to promote activation of thrombin-activatable fibrinolysis inhibitor (TAFI). These analogs are useful in, for example, antithrombotic therapy.

Abstract: The present invention relates to the design, production and use of analogs of thrombomodulin (TM) that have the ability to enhance the thrombin-mediated activation of protein C but which have a significantly reduced ability to promote activation of thrombin-activatable fibrinolysis inhibitor (TAFI). These analogs are useful in, for example, antithrombotic therapy.

Abstract: The present invention relates to the design, production and use of analogs of thrombomodulin (TM) that have the ability to enhance the thrombin-mediated activation of protein C but which have a significantly reduced ability to promote activation of thrombin-activatable fibrinolysis inhibitor (TAFI). These analogs are useful in, for example, antithrombotic therapy.

Abstract: Polymorphisms within a plasma carboxypeptidase designated plasma carboxypeptidase B (PCPB) have been identified. The relative distribution of these polymorphs in a patient's blood can be used to assess an individual's risk toward thrombotic disease.